Intranet Fakultät für Chemie und Pharmazie

Prof. Dr. Franz Bracher
Chair of Pharmaceutical/Medicinal Chemistry

Address

Prof. Dr. Franz Bracher
Department Pharmazie
- Zentrum für Pharmaforschung -
Ludwig-Maximilians-Universität München
Butenandtstr. 7, Haus C
81377 München
Germany

Office +49 (0)89 2180-77300 (Melanie Pfoser)
Phone +49 (0)89 2180-77301
Room-Nr. C3.054
Email franz.bracher@cup.uni-muenchen.de
Home page bracher.cup.uni-muenchen.de

Research Interests

  • Natural product chemistry (synthesis, biological activities)
  • Inhibitors of ergosterol and cholesterol biosynthesis as new drugs
  • Development of new, selective kinase inhibitors

Short CV

  • Studied pharmacy at the LMU Munich
  • 1986 PhD in Pharmaceutical Chemistry, LMU Munich
  • 1986-1987 Postdoctoral Researcher at the Department of Organic Chemistry, University of Geneve/Switzerland
  • 1991 Habilitation, University of Marburg
  • 1992-1997 C3 Professor, University of Braunschweig
  • Since 1997 C4 Professor for Pharmaceutical Chemistry, LMU Munich

Key publications

  • M. König. C. Müller, F. Bracher: Stereoselective synthesis of a new class of potent and selective inhibitors of human Δ8,7-sterol isomerase Bioorg. Med. Chem. 21, 1925-1943 (2013)
  • K. Huber K, L. Brault, O. Fedorov, C. Gasser, P. Filippakopoulos, A. N. Bullock, D. Fabbro, J. Trappe, J. Schwaller, S. Knapp, F. Bracher: 7,8-Dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes, J. Med. Chem. 55, 403-413 (2012)
  • K. Huber, J. Schemies, U. Uciechowska, J. M. Wagner, T. Rumpf, F. Lewrick, R. Süss, W. Sippl, M. Jung, F. Bracher: Novel 3-arylidene-indolin-2-ones as inhibitors of NAD+-dependent histone deacetylases (sirtuins), J. Med. Chem. 53 , 1383 (2010)