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Prof. Dr. Rasmus Linser

Address

Prof. Dr. Rasmus Linser
Department Chemie und Pharmazie
Ludwig-Maximilians-Universität München
Butenandtstr. 5-13, Haus F
81377 München
Germany

Phone +49 (0)89 2180-77652
Fax +49 (0)89 2180-77646
Room-Nr. F0.052
Email rasmus.linser@cup.lmu.de
Home page www.cup.lmu.de/oc/linser

Research Interests

  • NMR spectroscopy
  • Protein structure, dynamics, and function
  • Role of protons in enzymatic function

Short CV

  • 2001 - 2006: Studies in chemistry in Göttingen and at the Universidad Autónoma de Madrid (UAM), thesis in organic chemistry with Prof. Dr. Dr. h. c. Tietze.
  • 2006 - 2010: Doctorate studies with Prof. Dr. Bernd Reif at the Leibniz-Institute for Molecular Pharmacology, Berlin.
  • 2010 - 2011: Research scientist and conjoint lecturer at the Analytical Centre and School of Chemistry, UNSW, Sydney.
  • 2011 - 2014: Postdoc with Prof. Dr. Gerhard Wagner, Department Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston
  • 2012 - 2014: DECRA researcher, affiliated with School of Chemistry, University of New South Wales, Sydney, and Harvard Medical School, Boston
  • 2014 - 2016: Emmy Noether junior group leader at the Max Planck Institute for Biophysical Chemistry, Göttingen.
  • 2016 - : W2 professor for NMR spectroscopy at the Ludwig-Maximilians-University Munich.

Key publications

  • S. Xiang, J. Biernat, E. Mandelkow, S. Becker, R. Linser, “Sequential backbone assignment in fully protonated proteins at fast Magic-Angle Spinning”, ChemComm., DOI: 10.1039/C5CC09160H (2016), cover article.
  • R. Linser, N. Salvi, R. Briones, P. Rovó, B. de Groot, G. Wagner, “The Membrane Anchor of the Transcriptional Activator SREBP is Characterized by Intrinsic Conformational Flexibility”, Proc. Natl. Acad. Sci. USA, 112 (40) 12390-12395 (2015).
  • R. Linser, B. Bardiaux, S. G. Hyberts, A. Kwan, V. Morris, M. Sunde, G. Wagner, “Solid-State NMR Structure Determination from Diagonal-Compensated, Sparsely Nonuniform-Sampled 4D Proton–Proton Restraints”, J. Am. Chem. Soc. 136 (31), 11002–11010 (2014).
  • R. Linser, M. Dasari, U. Fink, P. Schmieder, J.-M. Lopez del Amo, S. Marcovic, M. Hiller, H. Oschkinat, D. Oesterheld, B. Reif, “Proton detected solid state NMR of fibrillar and membrane proteins”, Angew. Chem., Int. Ed. 50 (19), 4508–4512 (2011), cover article.