Carell Group

Organic and Biomolecular Chemistry

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R. R. Edupuganti, S. Geiger, R. G. H. Lindeboom, H. Shi, P. J. Hsu, Z. Lu, S.-Y. Wang, M. P. A. Baltissen, P. W. T. C. Jansen, M. Rossa, M. Müller, H. G. Stunnenberg, C. He*, T. Carell*, M. Vermeulen*
Nat. Struct. Mol. Biol., 2017, doi:10.1038/nsmb.3462
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

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R. Rahimoff, O. Kosmatchev, A. Kirchner, T. Pfaffeneder, F. Spada, V. Brantl, M Müller, T. Carell
J. Am. Chem. Soc, 2017, doi:10.1021/jacs.7b04131
5-Formyl- and 5-carboxydeoxycytidines do not cause accumulation of harmful repair intermediates in stem cells.

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B. Thienpont, J. Steinbacher, H. Zhao, F. D'Anna, A. Kuchnio, A. Ploumakis, B. Ghesquière, L. Van Dyck, B. Boeckx, L. Schoonjans, E. Hermans, F. Amant, V. N. Kristensen, K. P. Koh, M. Mazzone, M. L. Coleman, T. Carell, P. Carmeliet, D. Lambrechts
Nature, 2016, doi: 10.1038/nature19081
Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

Sidney Becker, Ines Thoma, Amrei Deutsch, Tim Gehrke, Peter Mayer, Hendrik Zipse, Thomas Carell
Science 2016, 352 (6287), 833-836 doi:10.1126/science.aad2808
A high-yielding, strictly regioselective prebiotic purine nucleoside formation pathway.

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Thomas Carell was awarded the Inhoffen Medal 2016

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Prof. Dr. Thomas Carell

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Fax: +49 (0)89 2180 77756