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Publications

2017

  • Kellner S.*, Demott M.*, Chen C., Cao B. and Dedon P. (2017) Oxidation of labile phosphorothioate DNA modifications leads to lethal genomic instability, Nature Chemical Biology, PMID: 28604692
  • Dewe JM, Fuller BL, Lentini JM, Kellner SM, Fu D. (2017) TRMT1-catalyzed tRNA modifications are required for redox homeostasis to ensure proper cellular proliferation and oxidative stress survival. Mol Cell Biol. doi: 10.1128/MCB.00214-17. PubMed PMID: 28784718.
  • Heiss, M., Reichle, V. & Kellner, S. (2017). Observing the fate of tRNA and its modifications by nucleic acid isotope labeling mass spectrometry: NAIL-MS. RNA Biol. 2017 May 10:0. doi: 10.1080/15476286.2017.1325063.

2016

  • Heiss, M., & Kellner, S. (2016). Detection of nucleic acid modifications by chemical reagents. RNA Biol. 2016 Nov 30:1-9. doi: 10.1080/15476286.2016.1261788.
  • Kaiser, S., Jurkowski, T. P., Kellner, S., Schneider, D., Jeltsch, A., & Helm, M. (2016). The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA. RNA Biol, 1-11. doi:10.1080/15476286.2016.1236170
  • Thiaville, J.J., et al., Novel genomic island modifies DNA with 7-deazaguanine derivatives. Proc Natl Acad Sci U S A, 2016.

2015

  • Schmid, K., et al., Variable presence of 5-methylcytosine in commercial RNA and DNA. RNA Biol, 2015. 12(10): p. 1152-8.
  • Lin, C.J., et al., An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis. RNA, 2015. 21(12): p. 2103-18.
  • Cai, W.M., et al., A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications. Methods Enzymol, 2015. 560: p. 29-71.
  • Bourgeois, G., et al., Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120. PLoS One, 2015. 10(7): p. e0133321.

2014

  • Spenkuch, F., et al., Dye label interference with RNA modification reveals 5-fluorouridine as non-covalent inhibitor. Nucleic Acids Res, 2014. 42(20): p. 12735-45.
  • Kellner, S., et al., Absolute and relative quantification of RNA modifications via biosynthetic isotopomers. Nucleic Acids Res, 2014. 42(18): p. e142.
  • Kellner, S., et al., Profiling of RNA modifications by multiplexed stable isotope labelling. Chem Commun (Camb), 2014. 50(26): p. 3516-8.
  • Buchhaupt, M., et al., Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification. PLoS One, 2014. 9(2): p. e89640.
  • Blanco, S., et al., Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J, 2014. 33(18): p. 2020-39.

2013

  • Kellner, S., et al., Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation. PLoS One, 2013. 8(7): p. e67945.

2012

  • Tuorto, F., et al., RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis. Nat Struct Mol Biol, 2012. 19(9): p. 900-5.
  • Sencilo, A., et al., Related haloarchaeal pleomorphic viruses contain different genome types. Nucleic Acids Res, 2012. 40(12): p. 5523-34.

2011

  • Kellner, S., et al., A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA. Nucleic Acids Res, 2011. 39(16): p. 7348-60.

2010

  • Kellner, S., J. Burhenne, and M. Helm, Detection of RNA modifications. RNA Biol, 2010. 7(2): p. 237-47.