Mayr's Database of Reactivity Parameters

Indole

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Name Indole
Structure
Molecule class Nucleophiles » C-Nucleophiles » Arenes » Indoles
SMILES C1(C=CC=C2)=C2NC=C1
Molecular formula C8H7N
Quality ***
Parameters

N  Param.: 5.55

sN Param.: 1.09
Comment N and sN were determined with reference electrophiles. Preliminary N and (estimated) sN values for indole (5.85/0.80, Chem. Eur. J. 2003, 9, 2209-2218) were rendered more precisely in 2006 after additional measurements with further reference electrophiles.
Solvent dichloromethane
Reference J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339