Intranet Fakultät für Chemie und Pharmazie

Prof. Dr. Ernst Wagner
Chair of Pharmaceutical Biology and Biotechnology - Biotechnology and Nanomedicine


Prof. Dr. Ernst Wagner
Department Pharmazie
- Zentrum für Pharmaforschung -
Ludwig-Maximilians-Universität München
Butenandtstr. 5-13, Haus D
81377 München

Office +49 (0)89 2180-77840 (Olga Brück)
Phone +49 (0)89 2180-77841
Room-Nr. D3.032
Home page

Research Interests

  • Crispr/Cas9, dsRNA, mRNA, pDNA,and siRNA therapeutics
  • Nanomedicine
  • Oncology

Short CV

  • 1985 PhD in Chemistry at the Technical University of Vienna/Austria
  • 1985-1987 Postdoctoral Researcher, ETH, Zurich/Switzerland
  • 1988-1995 Group Leader, Institute of Molecular Pathology, Vienna/Austria
  • 1992-2001, Director for Cancer Vaccines, Boehringer Ingelheim Austria
  • 1994 Habilitation, University of Vienna/Austria
  • 1995-2001 Group Leader, Institute of Biochemistry, Vienna/Austria
  • Since 2001 Professor (C4) for Pharmaceutical Biology-Biotechnology, LMU

Key publications

  • Schaffert, D. et al. (2011) Solid-phase synthesis of sequence-defined T-, i-, and U-shape polymers for pDNA and siRNA delivery. Angew. Chem. Int. Ed. 50, 8986-9.
  • Freitag, F., Wagner, E. (2021) Optimizing synthetic nucleic acid and protein nanocarriers: the chemical evolution approach. Adv. Drug Deliv. Rev. 168, 30-54.
  • Vetter, V.C., Wagner, E. (2022) Targeting nucleic acid-based therapeutics to tumors: challenges and strategies for polyplexes. J. Control. Rel. 346, 110-135.
  • Thalmayr, S. et al (2023) Molecular Chameleon Carriers for Nucleic Acid Delivery: The Sweet Spot Between Lipoplexes and Polyplexes. Adv. Mater. 35, e2211105.