Research Interests

  • Ion channels in brain and cardiovascular system
  • Endolysosomal ion channels
  • Genetic mouse models
  • Gene therapy

Short CV

  • Study of pharmacy, Universität des Saarlandes
  • 1990 Ph.D., Universität des Saarlandes
  • 1996 Habilitation, TU München
  • Since 1999 Professor for Pharmacology (C4), LMU München

Member of the German National Academy of Sciences Leopoldina and the Bavarian Academy of Sciences

Key publications

  • Fischer MD, Michalakis S,,,, Biel M, Wissinger B. (2020) Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial. JAMA Ophthalmol. DOI: 10.1001/jamaophthalmol.2020.1032.
  • Sakurai Y, Kolokoltsov AA, Chen CC, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA (2015) Two pore channels control Ebolavirus host cell entry and are drug targets for disease treatment. Science 347, 995-998.
  • Fenske S, Krause S, Hassan S, Becirovic E, Auer F, Bernard R, Kupatt C, Lange P, Ziegler T, Wotjak CT, Zhang H, Hammelmann V, Paparizos C, Biel M, and Wahl-Schott C. (2013) Sick sinus syndrome in HCN1 deficient mice. Circulation 128:2585-2594.
  • Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M (1998) A family of hyperpolarization-activated mammalian cation channels. Nature 393:587-591.