blank LMU Munich Faculty for Chemistry and Pharmacy


Independent research publications



Forging C-C Bonds through Intramolecular Oxidative Coupling of Organoborates – an Overview

D. Didier*

Synthesis 2022, doi: 10.1055/a-1757-2680

special issue dedicated to Prof. Alain Krief


Strain-Release Arylations for the Bis-Functionalization of Azetidines

Florian Trauner, Felix Reiners, Kodjo-Edmond Apaloo-Messan, Benedikt Nißl, Muhammad Shahbaz, Dongfang Jiang, Julian Aicher, Dorian Didier

Chem. Commun. 2022, 58, 2564-2567

part of the 2022 Pioneering Investigators themed edition

see also

preprint version:



Wie der Würfel wirkt

Florian Trauner, Muhammad Shabhaz, Dorian Didier*

Nach. Chem. 2021, 69 (Nov.), 72-75


Thietanes and Thietes: Monocyclic (Book chapter)

Comprehensive Heterocyclic Chemistry IV

Dorian Didier,* Felix Reiners, Andreas N. Baumann


Strategien bei der radikalischen Trifluoromethylierungen

Dorian Didier* and Felix Reiners

Nach. Chem. 2021, 69 (Juli), 70-74


Electro-alkynylation – Intramolecular Rearrangement of Trialkynylorganoborates for Chemoselective C(sp2)-C(sp) Bond Formation

Arif Music, Constantin M. Nuber, Yannick Lemke, Philipp Spieß, Dorian Didier*

Org. Lett. 2021, 23, 4179-4184


Computational Insights into Electrochemical Cross-Coupling of Quaternary Borate Salts

Florian Matz, Arif Music, Dorian Didier and Thomas-C. Jagau*

Electrochem. Sci. Adv. 2021, doi: 10.1002/elsa.202100032


Uncommon Four-Membered Building Blocks – Cyclobutenes, Azetines and Thietes

Dorian Didier* and Felix Reiners

The Chemical Record 2021, 21, 1144-1160


Nazarov-Elektrocyclisierung: neue Twists für eine Lehrbuchreaktion

Dorian Didier* and Felix Reiners

Nach. Chem. 2021, 69 (März), 72-75


Photocatalyzed Transition-Metal-Free Oxidative Cross-Coupling Reactions of Tetraorganoborates

Arif Music, Andreas N. Baumann, Florian Boser, Nicolas Müller, Florian Matz, Thomas C. Jagau and Dorian Didier*

Chem. Eur. J. 2021, 27, 4322-4326

see also

ChemRxiv 10.26434/chemrxiv.13005509.v1



Stereoselective Access to Azetidine-Based a-Aminoacids and Applications to Small Peptides Synthesis

Felix Reiners, Emanuel Joseph, Benedikt Nißl and Dorian Didier

Org. Lett. 2020, 22, 8533-8537

see also

ChemRxiv 10.26434/chemrxiv.12966803.v1

highlighted in Synfact


Electro‐olefination ‐ a Catalyst Free Stereoconvergent Strategy for the Functionalization of Alkenes

Andreas N. Baumann,+ Arif Music,+ Jonas Dechent, Nicolas Müller, Thomas C. Jagau and Dorian Didier*

Chem. Eur. J. 2020, 26, 8382-8387


Thiete Dioxides as Templates towards Novel Twisted Scaffolds and Macrocyclic Structures

Andreas N. Baumann,+ Felix Reiners,+ Alexander F. Siegle, Peter Mayer, Oliver Trapp, Dorian Didier*

Chem. Eur. J. 2020, 26, 6029-6035


Electrochemical Synthesis of Biaryls via Oxidative Intramolecular Coupling of Tetra(hetero)arylborates

Arif Music, Andreas N. Baumann, Philipp Spieß, Allan Plantefol, Thomas C. Jagau, Dorian Didier*

J. Am. Chem. Soc. 2020, 142, 4341-4348



Organocerium: A New Contender for Halogen/Metal Exchanges

Arif Music, Dorian Didier*

Synlett 2019, 30, 1843-1849 (invited synopsis article)


Single-Pot Access to Bisorganoborinates: Applications in Zweifel Olefination

Arif Music,+ Andreas N. Baumann,+ Philipp Spieß, Nicolas Hilgert, Martin Köllen, Dorian Didier*

Org. Lett. 2019, 21, 2189-2193


Catalyst-Free Enantiospecific Olefination with in-situ Generated Organocerium Species

Arif Music, Clément Hoarau, Nicolas Hilgert, Florian Zischka, Dorian Didier*

Angew. Chem. Int. Ed. 2019, 58, 1188-1192



Chemodivergent and Stereoselective Access to Fused Isoxazoline Azetidines and Thietanes through [3+2]-Cycloadditions

Andreas N. Baumann, Felix Reiners, Thomas Juli, Dorian Didier*

Org. Lett. 2018, 20, 6736-6740


Unsaturated Four-Membered N-Heterocycles: From Synthesis to Applications

Dorian Didier,* Andreas N. Baumann, Michael Eisold

Tetrahedron Lett. 2018, 59, 3975–3987


Parallel Approaches for the Functionalization of Thietes: α‑Metalation versus C−H Activation

Michael Eisold, Adrian Müller-Deku, Felix Reiners, Dorian Didier*

Org. Lett. 2018, 20, 4654-4658


Merging Art and Science - 53rd Bürgenstock Conference

J. Boekhoven,* D. Didier*

Angew. Chem. Int. Ed. 2018, 57,10011–10014


One-pot Preparation of Stable Organoboronate Reagents for the Functionalization of Unsaturated Four- and Five-Membered Carbo- and Heterocycles

A. N. Baumann,+ M. Eisold,+ A. Music,+ D. Didier*

Synthesis 2018 (Special Issue, invited) - online version


Oxidative Ring Contraction of Cyclobutenes – General Approach to Cyclopropylketones Including Mechanistic Insights

A. N. Baumann, F. Schüppel, M. Eisold, A. Kreppel, R. de Vivie-Riedle,* D. Didier*

J. Org. Chem. 2018, 83, 4905-4921 (Featured Article)

...among the most read in April 2018...


Regiodivergent Stereoselective Access to Fused Alkylideneazetidines

A. Music, A. N. Baumann, M. Eisold, D. Didier*

J. Org. Chem. 2018, 83, 783-792

pdf - just accepted



Methods for the Synthesis of Substituted Azetines

A. N. Baumann, M. Eisold, A. Music, G. Haas, Y. M. Kiw, D. Didier*

Org. Lett., 2017, 19, 5681–5684

- highlighted in OPR&D (November 2017)


Stereoselective Access to Alkylidenecyclobutanes through g-Selective Cross-Coupling Strategies

M. Eisold, D.Didier*

Org. Lett., 2017, 19, 4046–4049

- highlighted in SynFacts (October 2017)

- selected SynFact of the month


Stereoselective Sequence toward Biologically Active Fused Alkylidenecyclobutanes

A. N. Baumann, M. Eisold, D. Didier*

Org. Lett. 2017, 19, 2114–2117


Unsaturated Four-Membered Rings: Efficient Strategies for the Construction of Cyclobutenes and Alkylidenecyclobutanes

M. Eisold, A. N. Baumann. G. M. Kiefl, S. T. Emmerling, D. Didier*

Chem. Eur. J. 2017, 23, 1634-1644



Single-Pot Asymmetric Approach toward Enantioenriched Quaternary Stereocenter-Containing Alkylidenecyclobutanes
M. Eisold G. M. Kiefl, D. Didier*

Org. Lett. 2016, 18, 3022-3025


Highly diastereoselective approach to methylenecyclopropanes via boron-homologation / allyl-boration sequences
A. Baumann, A. Music, K. Karaghiosoff, D. Didier*

Chem. Commun. 2016, 52, 2529-2532



Highly Diastereoselective Synthesis of Methylenecyclobutanes by Merging Boron-Homologation and Boron-Allylation Strategies
M. Eisold, D. Didier*

Angew. Chem. Int. Ed. 2015, 54, 15884-15887

Postdoctoral publications


Stereoselective Synthesis and Reactions of Secondary Alkyllithium Reagents Functionalized at the 3-Position

K. Moriya, D. Didier, M. Simon, J. Hammann, G. Berionni, K. Karaghiosoff, H. Zipse, H. Mayr, P. Knochel

Angew. Chem. Int. Ed. 2015, 54, 2754–2757


Preparation and Regioselective Magnesiation or Lithiation of Bis(trimethylsilyl)methyl-Substituted Heteroaryls for the Generation of Highly Functionalized Heterocycles

T. Klatt, V. Werner, . G. Maximova, D. Didier, Y. Apeloig, P. Knochel

Chem. Eur. J. 2015, 21, 7830-7834


Zirconocene-Mediated Selective and Versatile C-C Bond Cleavage of Strained Carbocycles: Scope and Mechanism

J. Bruffaerts, A. Vasseur, S. Singh, A. Masarwa, D. Didier, L. Oskar, L. Perrin, O. Eisenstein, I. Marek

J. Org. Chem. 2018 - ASAP


Diastereodivergent combined carbometalation/zinc homologation/C–C fragmentation reaction as an efficient tool to prepare acyclic allylic quaternary carbon stereocenters

S. R. Roy, D. Didier, A. Kleiner, I. Marek

Chem. Sci. 2016, 7, 5989-5994


Recent Advances in Acyclic Stereocontrol

G. Eppe, D. Didier, I. Marek

Chem. Rev. 2015, 115, 9175-9206


A Unique Merging of Allylic C-H and Selective C-C Bond Activation en Route to All-Carbon Quaternary Stereogenic Centers

A. Masarwa, D. Didier, T. Zabrodski, M. Schinkel, L. Ackermann, I. Marek

Nature 2014, 505, 199-203


Modulable and highly diastereoselective carbometallation of cyclopropenes

D. Didier, P.-O. Delaye, M. Simaan, B. Island, G. Eppe, H. Eijsberg, A. Kleiner, P. Knochel, I. Marek

Chem. Eur. J. 2014, 20, 1038-1048– Cover, January 2014


Carbometalation-Oxidation-Ring opening of cyclopropenes : en route to aldehydes bearing α-quaternary stereocenters

P.-O. Delaye, D. Didier, I. Marek

Angew. Chem. Int. Ed. 2013, 52, 5333-5337 – Highlighted in Synfacts 2013, 877


Copper catalysed asymmetric synthesis

in Carbometallation reactions (Chapter 10), D. Didier, I. Marek ; eds: A. Alexakis, N. Krause, S. Woodward

Wiley-VCH 2014, 267-282

PhD publications


Immobilization of an anthracene-tagged Ru complex on a TNF-grafted silica: efficiency and recyclability in olefin metathesis reactions

H. Nasrallah, A. Pagnoux, D. Didier, C. Magnier, L. Toupet, R. Guillot, C. Crévisy, M. Mauduit, E. Schulz

Eur. J. Org. Chem. 2014, 7781-7787


Pi-stacking interactions at the [Cu]-bis(oxazoline)’s recycling service

D. Didier, E. Schulz

Tetrahedron: Asymmetry 2013, 24, 769-775


Reusable TNF-tagged chiral bis(oxazoline)-copper catalyst for Diels-Alder transformations

D. Didier, E. Schulz

Synlett 2012, 23, 1309-1314


Recycling chiral copper-bis(oxazoline) complexes in an original multi-reactions procedure

D.Didier, E. Schulz

ChemCatChem 2011, 3, 1880-1884


Charge-transfer interactions : an efficient tool for the easy recovery of bis(oxazoline)-copper complexes, active catalysts in the asymmetric Henry reaction

D. Didier, C. Magnier-Bouvier, E. Schulz

Adv. Synth. Catal. 2011, 353, 1087-1095


Reausable chiral bis(oxazoline)-copper complexes immobilized by donnor-acceptor interactions on insoluble supports

G. Chollet, D. Didier, E. Schulz

Catalysis Communication 2010, 11, 351-355


Enantioselective aza-Michael additions catalyzed by samarium iodo binaphtholate

D. Didier, A. Meddour, S. Bezzenine-Lafollée, J. Collin

Eur. J. Org. Chem. 2011, 2678-2684