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Arbeitskreis Kellner: News

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07. 09. 2020

Hurina started her Master thesis. Welcome Hurina!

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04. 09. 2020

Valentin defended his thesis and is now Dr. Reichle! Congrats!

here will be a picture soon

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22. 07. 2020

We hire! Join our team!

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22. 07. 2020

Felix worked together with Dragony Fu and found a connection between tRNA wobble inosine and intellectual disability.

Link to the paper!

Nice job Felix!

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01. 07. 2020

In a great effort Steffen elucidated the role and impact of METTL6 on m3C formation in tRNA together with Rob Schneider and his team.

Check it out here!

Nice job Steffen!

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18. 06. 2020

Life without wobble-U? Read all about it in our latest NAR paper!

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25. 05. 2020

Yasi is our great science blogger and her reach was increased through an LMU interview.

Nice job Yasi!

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12. 05. 2020

Christoph's and Valentin's paper on 4-methylthiouridine in bacterial tRNA was accepted at ChemBioChem!

To the paper

Congratulations Christoph and Valentin!

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01. 05. 2020

Gregor joined our lab as a PhD student. Welcome Gregor!

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17. 04. 2020

Yasi was interviewed!

To the interview

Congratulations Yasi!

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26.03.2020

Anbei eine schöne Anleitung der GDCh wie man provisorisch Atemmasken mit Küchenrolle, Gummiband und Tacker herstellen kann.

Viele weitere spannende Links der GDCh zum Thema: Chemiker helfen in der Corona Krise hier.

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25.03.2020

Overview of WHO-1 (ethanol based ~ 10€/5L) and WHO-2 (isopropanol based ~ 6€/5L) hand desinfectant.

Desinfektionsmittel Herstellprotokoll Etikett
Desinfektionsmittel auf Ethanolbasis mit 96 % Ethanol Etikett
Desinfektionsmittel auf Ethanolbasis mit 99 % Ethanol Etikett
Desinfektionsmittel auf Isopropanolbasis mit 99% Isopropanol Etikett

Auch Sachspenden (Atemmasken - jede Art) sowie Schutzbrillen, Kittel und Handschuhe werden dringend benötigt.

Denkt an die Sachspendebescheinigung!

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22.03.2020

Beim Hackathon der Bundesregierung sind 2 Plattformen entstanden, die Laborleiter/Innen (und Hochschulleitungen - Respekt an die TUM!) in Deutschland helfen können ihre Handschuhe, Schutzkleidung und Desinfektionsmittel an Ärzte, Pflegeheime, Bahnhofsmissionen (etc.) mit Bedarf zu verteilen.

Medimatch

Remedymatch

Bitte die Youtube Videos "liken" damit die Projekte von der Regierung gefördert werden und schnell (innerhalb von Tagen!) nutzbar sind.

Ich halte euch mittels dieser Website, Twitter (@Kellnerlab) und Instagram (@kellner_lab) auf dem Laufenden.

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21.03.2020

Die Bundesanstalt für Arbeitsschutz und Arbeitsmedizin hat die Herstellerlaubnis für Handdesinfektionsmittel gelockert:

Zum Originaltext

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Labstocks for local health care providers

Dear colleagues,

the Corona pandemic is a threat to us all. Now that most of us have closed down the lab, the question is:

What can we do?

Here is our idea:

  1. Ask your local health care providers (Hausärzte, Kinderärzte, etc.) what they need. The government is helping them – but most of them need e.g. masks and disinfectants now and not by the end of next week!
  2. Raid your lab of safety equipment like gloves, goggles and masks (!)
  3. If you have access to chemicals: Prepare canisters with hand disinfectant (WHO)

How to prepare hand disinfectant (WHO)

  1. Register your lab here (if you are based in Germany): LINK
  2. Go to your chemical storage – if you are already shut down, contact your president and ask them for support. The chemicals needed for disinfectant do not help in the crisis if they are locked away! Maybe the following sentences will help in the generation of your email to the president or dean: Email template
  1. Print the Herstellungsprotokoll (WHO-II) and follow it. For every 5L you prepare set a new Charge.-Nr., print and sign.
  2. Enter the Charge Nr. in the label template – print it
  3. Put the label on the canister

We are not sure whether these measures cover all potential legal issues. This is just a guideline of the things that you might need to consider. Legal consequences are possible after the crisis – following our suggestion is at your own risk.

Bringing items to health care providers:

  1. Print the “Spendenbescheinigung” and write down everything you bring to a particular health care provider.
  2. The health care provider should use their seal, date and and signature on it when you give them the items FOR FREE.

This is important – this way you can proof that you did not make a personal profit from the crisis by spending your lab funds.

Otherwise – stay safe – stay home

Stefanie Kellner

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18. 03. 2020

Due to the EU Corona outbreak, we have shut down the lab.

This was a tough decision as our junior group had just built momentum (just see our awesome publications this and last year!)

Stefanie and her team believe that this is the best way to serve mankind at the moment.

In the meantime, we will work on cool Methods and Review papers such as:

  • Quantification of modified nucleosides in the context of NAIL-MS
  • Detection of modified ribonucleosides (that one will be huge)
  • Structure and function of RNA demethylases

*** Desinfektionsmittel und Handschuhe ***

Der AK Kellner hat noch Vorräte an Desinfektionsmitteln und Handschuhen. Falls Ihre Arztpraxis in München Bedarf hat, melden Sie sich bei Stefanie Kellner:

stkech (ät) cup.lmu.de

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09. 03. 2020

We joined forces with the Carell Lab and our work on Q and its sugar modified derivatives was accepted today at Angewandte Chemie!

To the paper

Congratulations Matthias and Carell group members!

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06. 03. 2020

Steffen, Kayla and Erik collaborated with Robert Schneider and their results on METTL5 are now accepted at Genes&Development!

To the paper

Congratulations Steffen, Kayla and Erik!

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18. 02. 2020

Steffen collaborated with Matthias Schäfer and got his work on tRNA fragments accepted at RNA Biology!

To the paper

Congratulations Steffen!

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11. 02. 2020

Let's celebrate women in science - go for it girls!

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06. 02. 2020

Check out our new group picture

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04. 02. 2020

Felix and Kaylas work on oligonucleotide mass spectrometry got accepted at NAR Methods!

To the manuscript

Congratulations Felix & Kayla!

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01. 01. 2020

Kati joined our group as a PhiP

Welcome Kati!

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11. 12. 2019

Steffen collaborated with Jens Wöhnert and got his work on a tRNA modifcation enzyme accepted at Nucleic Acids Research!

Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs

Congratulations Steffen!

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10. 12. 2019

LMU press release:

Methylation and mopping up

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14. 11. 2019

Valentin's paper "NAIL-MS reveals the repair of 2-methylthiocytidine by AlkB in E. coli" is accepted in Nature Communications.

Click here for the Journal Website

Congratulations Valentin!

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08. 2019

Stefanie is Guest-Editor at Genes for the Special Issue "Function and Dynamics of RNA modifications"

Click here for the Journal Webpage.

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01. 08. 2019

Christoph joined our group as a Postdoc. Welcome :-)

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Papers getting accepted

Felix and Matze collaborated with Dragony Fu, Michaela Frye and Pierre Barraud - now their work has been published. Congratulations!

Felix: Formation of tRNA wobble inosine ...

Matze: Cytosine-5 RNA methylation links protein synthesis to cell metabolism

Matze: Time-resolved NMR monitoring of tRNA maturation

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08. 04. 2019

Erik started his master thesis. Welcome :-)

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11. 03. 2019

Paria's review "Benefits of stable isotope labeling in RNA analysis" is accepted in Biological Chemistry

To the manuscript

Congratulations Paria!

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06. 02. 2019

Stefanie explains her love for RNA modifications and NAIL-MS in this short video:

Click here

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05. 01. 2019

Kayla's manuscript "Production and Application of Stable Isotope-Labeled Internal Standards for RNA Modification Analysis" is published in Genes

To the manuscript

Congratulations Kayla!

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20. 12. 2018

Our latest manuscript made it to the front cover of ChemBioChem

https://onlinelibrary.wiley.com/toc/14397633/2018/19/24

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22. 11. 2018

Our new group picture

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12. 11. 2018

Yasi re-joined our group as a PhD student.

Welcome Yasi! :-)

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02. 11. 2018

Our group effort "Surpassing limits of static RNA modification analysis with dynamic NAIL-MS" is accepted by Methods

To the manuscript

Congratulations Kellner lab!

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17. 10. 2018

Valentin got his work on "NAIL-MS in E. coli determines the source and fate of methylation in tRNA" accepted by ChemBioChem

To the manuscript

Congratulations Valentin and Verena!

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08. 10. 2018

Linda joined our group as a Pharmaziepraktikant.

Welcome Linda! :-)

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07. 10. 2018

Valentin won the NAR sponsored poster prize at the GBM study group meeting "RNA Biology" 2018.

Congratulations Valentin!

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17. 09. 2018

Paria joined our group as a PhD student.

Welcome Paria! :-)

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07-09. 09. 2018

Stefanie was invited to the 2018 GAIN in Boston. In the Kick-off Impulse session she shared her experiences from her time at the MIT in Boston.

Find her interview here.

#GOGAIN18

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01. 07. 2018

The AK Kellner will be funded for 4 years by the Sonderforschungsbereich 1309 of the DFG. Our topic will be

Discovery of novel RNA modifications and targets of RNA writer enzymes

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01. 06. 2018

The AK Kellner will be funded for 3 years by the Schwerpunktprogram SPP 1784 of the DFG. Our topic will be

New tools for RNA modification dynamics analysis

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01. 06. 2018

Kayla joined our group as a PostDoc.

Welcome Kayla! :-)

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02. 05. 2018

Frühlingsfest @Theresienwiese resulted in our new group picture.

Nice!

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13. 02. 2018

Our QQQ mass spectrometer got installed. What a box!

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01. 01. 2018

Felix has finished his Masters Thesis and started his PhD.

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27.09.2017

We have moved to building B, 2nd floor

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15.09.2017

Verena is now supporting the lab as a HiWi. Welcome!

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13.09.2017

Our first AK trip - what a hike - and what a view!

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12.09.2017

Yasi made the most amazing poster of all RNA modifications!

Thank you Yasi for joining our lab and have fun with your next internship in Oxford! It was great to have you in the lab :-)

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17.07.2017

Finally official :-) Stefanie will be funded by the Emmy-Nöther program of the DfG.

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12.06.2017

Modify and Die!

Bacteria modifying their DNA with sulfur die from oxidation induced genomic instability - find Stefanie's latest article here: https://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.2407.html

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01.06.2017

Matthias started his PhD. Welcome :-)

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22.05.2017

Felix started his master thesis. Welcome :-)

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10.05.2017

Matthias and Valentin's paper on nucleic acid isotope labeling in yeast got accepted at RNA Biology - Congrats :-)

http://www.tandfonline.com/doi/abs/10.1080/15476286.2017.1325063?journalCode=krnb20

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03.04.2017

Yasemin started working in the Kellner Lab. Welcome :-)

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01.03.2017

Valentin and Stefanie wrote a "Trendbericht der Biochemie" for the "Nachrichten der Chemie".

Check it out at:

https://www.gdch.de/fileadmin/blaetterkatalog/trendb2016/blaetterkatalog/index.html#page_94

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01.03.2017

Stefanie was invited to the 67th Nobel Laureate Meeting.

http://www.lindau-nobel.org/de/

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03.01.2017

Felix started his internship. Welcome!

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08.12.2016

Heiss, M., and Kellner, S. (2016). Detection of nucleic acid modifications by chemical reagents. RNA Biol, 0. doi:10.1080/15476286.2016.1261788

Congratulations Matthias!

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01.11.2016

Valentin has started his PhD.

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01.10.2016

Thanks to AnnK-Design for this wonderful lab logo.

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05.09.2016

Matthias started his Master thesis.

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02.09.2016

Lab is up an running

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01.06.2016

Los geht's!