Mayr's Database of Reactivity Parameters

Nucleophiles

6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 Found 1357 molecules, displaying page 13 of 14 Results per page 10|50|100|all
Name Solvent Reactivity
Parameters 		Classification Reference
(title or year)
furan
C4H4O*
 dichloromethane

N  Param.: 1.33

sN Param.: 1.29		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
2-phenyl-4-(trimethylsilyl)but-1-en-3-ynyl-Co2(CO)6
*
 dichloromethane

N  Param.: 1.33

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(3-chlorobenzyl)dimethylsilane
C9H13ClSi*
 dichloromethane

N  Param.: 1.30

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
allyltriphenylgermane
C21H20Ge*
 dichloromethane

N  Param.: 1.20

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
1-methylcyclopentene
C6H10*
 dichloromethane

N  Param.: 1.18

sN Param.: 1.17		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
(E,E)-hexa-2,4-diene
C6H10*
 dichloromethane

N  Param.: 1.17

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2,3-dimethyl-buta-1,3-diene
C6H10*
 dichloromethane

N  Param.: 1.17

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
methylenecyclohexane
C7H12*
 dichloromethane

N  Param.: 1.16

sN Param.: 1.04		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
2,5-dimethyl-hexa-1,5-diene
C8H14*
 dichloromethane

N  Param.: 1.14

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-methylpropene (isobutylene)
C4H8*
 dichloromethane

N  Param.: 1.11

sN Param.: 0.98		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
trifluoroethanol
C2H3F3O*
 TFE

N  Param.: 1.11

sN Param.: 0.96		***J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
2-methyl-buta-1,3-diene (isoprene)
C5H8*
 dichloromethane

N  Param.: 1.10

sN Param.: 0.98		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
2-methyl-but-1-ene
C5H10*
 dichloromethane

N  Param.: 1.00

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
10% water/90% HFIP (w/w)
*
 water-HFIP mix

N  Param.: 0.96

sN Param.: 0.93		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
trimethyl(prenyl)silane
C8H18Si*
 dichloromethane

N  Param.: 0.90

sN Param.: 1.17		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
methyl(neopentyl)(phenyl)silane
C12H20Si*
 dichloromethane

N  Param.: 0.87

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-methyl-pent-1-ene
*
 dichloromethane

N  Param.: 0.84

sN Param.: 1.06		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
(chloromethyl)dimethylsilane
C3H9ClSi*
 dichloromethane

N  Param.: 0.80

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2,4,4-trimethyl-pent-1-ene
C8H16*
 dichloromethane

N  Param.: 0.79

sN Param.: 1.07		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
chlorodimethylsilane
C2H7ClSi*
 dichloromethane

N  Param.: 0.79

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
styrene
C8H8*
 dichloromethane

N  Param.: 0.78

sN Param.: 0.95		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
(1S)-(-)-alpha-pinene
C10H16*
 dichloromethane

N  Param.: 0.68

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2,4,6-trimethylstyrene
C11H14*
 dichloromethane

N  Param.: 0.68

sN Param.: 1.09		***Macromolecules 2005, 38, 33-40
10.1021/ma048389o
cyclohexa-1,3-diene
C6H8*
 dichloromethane

N  Param.: 0.67

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(Z)-penta-1,3-diene
C5H8*
 dichloromethane

N  Param.: 0.66

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-methyl-but-2-ene
C5H10*
 dichloromethane

N  Param.: 0.65

sN Param.: 1.17		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
2,3-dimethyl-but-1-ene
C6H12*
 dichloromethane

N  Param.: 0.65

sN Param.: 1.00		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
xanthene
C13H10O*
 dichloromethane

N  Param.: 0.64

sN Param.: 0.97		*J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
alpha-(pentamethyldisilyl)styrene
C13H22Si2*
 dichloromethane

N  Param.: 0.61

sN Param.: 1.01		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
2-(tris(pentafluorophenyl)siloxy)-propene
C21H5F15OSi*
 dichloromethane

N  Param.: 0.58

sN Param.: 0.91		*Eur. J. Org. Chem. 2005, , 1760-1764
10.1002/ejoc.200400706
cycloheptatriene (in MeCN)
C7H8*
 MeCN

N  Param.: 0.55

sN Param.: 0.97		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2,4-dimethyl-penta-1,4-diene
C7H12*
 dichloromethane

N  Param.: 0.54

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
cycloheptatriene
C7H8*
 dichloromethane

N  Param.: 0.52

sN Param.: 0.97		*J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
2-diazobenzothiophen-3(2H)-one
C8H4N2OS*
 dichloromethane

N  Param.: 0.40

sN Param.: 0.93		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
1,4-cyclohexadiene (in MeCN)
*
 MeCN

N  Param.: 0.35

sN Param.: 0.98		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
7% water/93% HFIP (w/w)
*
 water-HFIP mix

N  Param.: 0.34

sN Param.: 0.96		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
(2-methylallyl)benzene
C10H12*
 dichloromethane

N  Param.: 0.25

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(4-methoxyphenethyl)trimethylstannane
*
 1,2-dichloroethane

N  Param.: 0.20

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
hexylsilane
*
 dichloromethane

N  Param.: 0.19

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-diazoindandione
C9H4N2O2*
 dichloromethane

N  Param.: 0.16

sN Param.: 0.86		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
3-methylanisole
C8H10O*
 dichloromethane

N  Param.: 0.13

sN Param.: 1.27		***J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
tetraethylplumbane (in MeCN)
*
 MeCN

N  Param.: 0.10

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,4-cyclohexadiene
C6H8*
 dichloromethane

N  Param.: 0.09

sN Param.: 0.98		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
1-methylcyclohexene
C7H12*
 dichloromethane

N  Param.: 0.08

sN Param.: 1.15		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
phenylsilane
C6H8Si*
 dichloromethane

N  Param.: 0.06

sN Param.: 0.71		***Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2,3,3-trimethyl-but-1-ene
C7H14*
 dichloromethane

N  Param.: 0.06

sN Param.: 1.07		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
cyclohepta-1,3-diene
C7H10*
 dichloromethane

N  Param.: 0.06

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
phenylacetylene
C8H6*
 dichloromethane

N  Param.: -0.04

sN Param.: 0.77		***Angew. Chem. Int. Ed. 2014, 53, 4968-4971
10.1002/anie.201402055
1,4-dihydronaphthalene
C10H10*
 dichloromethane

N  Param.: -0.07

sN Param.: 1.03		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
5% water/95% HFIP (w/w)
*
 water-HFIP mix

N  Param.: -0.10

sN Param.: 0.97		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
(1H-inden-1-yl)trimethylsilane (in CH2Cl2)
C12H16Si*
 dichloromethane

N  Param.: -0.10

sN Param.: 1.05		***Angew. Chem. Int. Ed. 2015, 54, 12497-12500
10.1002/anie.201501385
allyltriphenylsilane
C21H20Si*
 dichloromethane

N  Param.: -0.13

sN Param.: 1.21		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
norbornene
C7H10*
 dichloromethane

N  Param.: -0.25

sN Param.: 1.09		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
2-(pentamethyldisilyl)propene
C8H20Si2*
 dichloromethane

N  Param.: -0.26

sN Param.: 0.95		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
tetrabutylstannane
*
 dichloromethane

N  Param.: -0.30

sN Param.: 1.07		***Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(4-(tert-butyl)phenethyl)trimethylstannane
*
 1,2-dichloroethane

N  Param.: -0.30

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-(tris(trimethylsilyl)silyl)propene
C12H32Si4*
 dichloromethane

N  Param.: -0.31

sN Param.: 0.99		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
diethyl diazomalonate
C7H10N2O4*
 dichloromethane

N  Param.: -0.35

sN Param.: 0.93		**Chem. Eur. J. 2003, 9, 4068-4076
10.1002/chem.200304913
beta-(trimethylsilyl)styrene
C11H16Si*
 dichloromethane

N  Param.: -0.43

sN Param.: 1.06		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
1-ethinylcyclohexenyl-Co2(CO)6
*
 dichloromethane

N  Param.: -0.44

sN Param.: 1.06		***J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
methylenecyclopropane
C4H6*
 dichloromethane

N  Param.: -0.47

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(E)-propenylbenzene
C9H10*
 dichloromethane

N  Param.: -0.49

sN Param.: 1.18		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
cycloocta-1,3-diene
C8H12*
 dichloromethane

N  Param.: -0.50

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
tetrapropylstannane (in 1,2-DCE)
*
 1,2-dichloroethane

N  Param.: -0.50

sN Param.: 1.13		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
trimethyl(4-methylphenethyl)stannane
*
 1,2-dichloroethane

N  Param.: -0.50

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
allylchlorodimethylsilane
C5H11ClSi*
 dichloromethane

N  Param.: -0.57

sN Param.: 1.06		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
(2-methylallyl)trichlorosilane
C4H7Cl3Si*
 dichloromethane

N  Param.: -0.57

sN Param.: 0.95		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
4,4,5,5-tetramethyl-2-prop-2-enyl-1,3,2-dioxaborolane (in CH2Cl2)
C9H17BO2*
 dichloromethane

N  Param.: -0.64

sN Param.: 1.10		***J. Am. Chem. Soc. 2017, 139, 15324-15327
10.1021/jacs.7b10240
1-(p-tolyl)-1-(trimethylsilyl)ethene
C12H18Si*
 dichloromethane

N  Param.: -0.65

sN Param.: 1.59		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
diethylmercury (in MeCN)
*
 MeCN

N  Param.: -0.70

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
4-methyl-2,5-heptadiene
C8H14*
 dichloromethane

N  Param.: -0.73

sN Param.: 0.97		*J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
(E,E)-2,5-heptadiene
C7H12*
 dichloromethane

N  Param.: -0.74

sN Param.: 0.99		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
4-(trimethylsilyl)but-1-en-3-ynyl-Co2(CO)5(PPh3)
*
 dichloromethane

N  Param.: -0.76

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-(trimethylsilyl)thiophene
C7H12SSi*
 dichloromethane

N  Param.: -0.80

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(2-([1,1'-biphenyl]-4-yl)ethyl)trimethylstannane
*
 1,2-dichloroethane

N  Param.: -0.80

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
9,10-dihydroanthracene
C14H12*
 dichloromethane

N  Param.: -0.86

sN Param.: 0.92		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
buta-1,3-diene
C4H6*
 dichloromethane

N  Param.: -0.87

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
3-propylcyclopentene
C8H14*
 dichloromethane

N  Param.: -0.88

sN Param.: 0.94		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
2-phenyldioxolane
C9H10O2*
 dichloromethane

N  Param.: -0.90

sN Param.: 0.80		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
HW(CO)3(C5H4CO2Me)
*
 dichloromethane

N  Param.: -0.90

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
tetramethylethylene
C6H12*
 dichloromethane

N  Param.: -1.00

sN Param.: 1.40		***Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
trimethyl(3-(trimethylplumbyl)propyl)germane (in MeCN)
*
 MeCN

N  Param.: -1.00

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
thiophene
C4H4S*
 dichloromethane

N  Param.: -1.01

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-propyl-1,3-dioxolane
C6H12O2*
 dichloromethane

N  Param.: -1.06

sN Param.: 0.81		***Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(Z)-phenylpropene
C9H10*
 dichloromethane

N  Param.: -1.07

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
tetra-sec.butylstannane (in 1,2-DCE)
*
 1,2-dichloroethane

N  Param.: -1.10

sN Param.: 1.15		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
trimethyl(phenethyl)stannane
*
 1,2-dichloroethane

N  Param.: -1.10

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
4-(trimethylsilyl)but-1-en-3-ynyl-Co2(CO)6
*
 dichloromethane

N  Param.: -1.11

sN Param.: 0.92		***J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
alpha-(trimethylsilyl)styrene
C11H16Si*
 dichloromethane

N  Param.: -1.13

sN Param.: 1.46		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
anisole
C7H8O*
 dichloromethane

N  Param.: -1.18

sN Param.: 1.20		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
3% water/97% HFIP (w/w)
*
 water-HFIP mix

N  Param.: -1.19

sN Param.: 1.08		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
trimethyl(3-(trimethylplumbyl)propyl)silane (in MeCN)
*
 MeCN

N  Param.: -1.20

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
dimethyl diazomalonate
C5H6N2O4*
 dichloromethane

N  Param.: -1.24

sN Param.: 0.81		***J. Am. Chem. Soc. 2023, 145, 7416-7434
10.1021/jacs.2c13872
2-(trimethylsilyl)propene
C6H14Si*
 dichloromethane

N  Param.: -1.46

sN Param.: 1.05		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
cyclopentene
C5H8*
 dichloromethane

N  Param.: -1.55

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2% water/98% HFIP (w/w)
*
 water-HFIP mix

N  Param.: -1.62

sN Param.: 1.10		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
1,3-bis(trimethylstannyl)propane (in MeCN)
*
 MeCN

N  Param.: -1.70

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
triethoxysilane
C6H16O3Si*
 dichloromethane

N  Param.: -1.80

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(4-chlorophenethyl)trimethylstannane
*
 1,2-dichloroethane

N  Param.: -1.80

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
tetraethylstannane (in 1,2-DCE)
*
 1,2-dichloroethane

N  Param.: -1.90

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839