Mayr's Database of Reactivity Parameters

C-Nucleophiles

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Name Solvent Reactivity
Parameters
Classification Reference
(title or year)
1-(perfluorophenyl)-1-(trimethylsiloxy)ethene
*
dichloromethane

N  Param.: 1.47

sN Param.: 0.89
*** Org. Lett. 2012, 14, 3990-3993
10.1021/ol301766w
(E)-penta-1,3-diene
C5H8 *
dichloromethane

N  Param.: 1.49

sN Param.: 1.00
* Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
methylenecyclododecane
C13H24 *
dichloromethane

N  Param.: 1.52

sN Param.: 0.90
* Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-(tributylstannyl)thiophene
C16H30SSn *
dichloromethane

N  Param.: 1.53

sN Param.: 1.00
* Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
3,4-dimethoxy-2-(methoxymethyl)-3,4-dihydro-2H-pyran
C9H16O4 *
dichloromethane

N  Param.: 1.53

sN Param.: 1.38
*** Angew. Chem. Int. Ed. 2026, 65, e24329
10.1002/anie.202524329
2,7-dimethylocta-1,7-diene
C10H18 *
dichloromethane

N  Param.: 1.58

sN Param.: 1.00
* Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
methylenecyclobutane
C5H8 *
dichloromethane

N  Param.: 1.65

sN Param.: 0.90
* Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
allyltrimethylsilane
C6H14Si *
dichloromethane

N  Param.: 1.68

sN Param.: 1.00
***** J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
tert-butyl indole-1-carboxylate
C13H15NO2 *
MeCN

N  Param.: 1.68

sN Param.: 1.26
*** J. Am. Chem. Soc. 2013, 135, 6317-6324
10.1021/ja4017655
methylenecyclopentadecane
C16H30 *
dichloromethane

N  Param.: 1.69

sN Param.: 0.90
* Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c