Mayr's Database of Reactivity Parameters

Enamines, Enamides, and Ynamides

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Name Solvent Reactivity
Parameters
Classification Reference
(title or year)
1-(phenylethynyl)pyrrolidin-2-one
C12H11NO *
dichloromethane

N  Param.: 3.12

sN Param.: 0.85
* Angew. Chem. Int. Ed. 2014, 53, 4968-4971
10.1002/anie.201402055
1-(phenylmethylamino)cyclohexene
C13H17N *
dichloromethane

N  Param.: 10.73

sN Param.: 0.81
*** Chem. Eur. J. 2003, 9, 2209-2218
10.1002/chem.200204666
1-(phenylmethylamino)cyclopentene
C12H15N *
dichloromethane

N  Param.: 12.90

sN Param.: 0.79
*** Chem. Eur. J. 2003, 9, 2209-2218
10.1002/chem.200204666
1-methyl-4-(N-morpholino)tetrahydropyridine
C10H18N2O *
dichloromethane

N  Param.: 12.03

sN Param.: 0.80
* Chem. Eur. J. 2003, 9, 2209-2218
10.1002/chem.200204666
1-pyrrolidino-3,4-dihydronaphthalene (in MeCN)
C14H17N *
MeCN

N  Param.: 14.09

sN Param.: 0.66
*** Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
2-((2,2,5,5-tetramethyl-1-(prop-1-en-1-yl)-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C12H19N3S *
MeCN

N  Param.: 9.25

sN Param.: 0.84
*** Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-((2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in CH2Cl2)
C17H21N3S *
dichloromethane

N  Param.: 7.06

sN Param.: 1.11
*** Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-((2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C17H21N3S *
MeCN

N  Param.: 7.74

sN Param.: 0.87
*** Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-(bis(tert-butyldimethylsiloxy)amino)propene
C15H35NO2Si2 *
dichloromethane

N  Param.: 4.23

sN Param.: 0.93
*** J. Org. Chem. 2001, 66, 3196-3200
10.1021/jo0015927
2-(bis(trimethylsiloxy)amino)propene
C9H23NO2Si2 *
dichloromethane

N  Param.: 4.76

sN Param.: 0.86
*** J. Org. Chem. 2001, 66, 3196-3200
10.1021/jo0015927