Publications Wolfgang Rödl

Papers

Rödl, W., Taschauer, A., Schaffert, D., Wagner, E., Ogris, M. (2019) Synthesis of polyethylenimine based nanocarriers for systemic tumor targeting of nucleic acids, Methods Mol Biol. 2019;1943:83-99
Urbiola, K., Blanco-Fernández, L., Ogris, M., Rödl, W., Wagner, E., Tros de Ilarduya, C. (2018) Novel PAMAM-PEG-peptide conjugates for siRNA delivery targeted to the transferrin and epidermal growth factor receptors, J Pers Med. 2018 Jan 9;8(1)
Urnauer S., Müller A. M., Schug, C., Schmohl, K.A., Tutter, M., Schwenk, N., Rödl, W., Morys, S., Ingrisch, M., Bertram, J., Bartenstein, P., Clevert, D.A., Wagner, E., Spitzweg, C. (2017) EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases, Oncotarget. 2017 Sep 16;8(54):92195-92208
Urnauer, S., Klutz, K., Grünwald, G.K., Morys, S., Schwenk, N., Zach, C., Gildehaus, F.J., Roedl, W., Ogris, M., Wagner, E., Spitzweg, C. (2017) Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes, J Gene Med. 2017 May;19(5)

Liu X, Zhang P, Rödl W, Maier K, Lächelt U, Wagner E. (2017) Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains, Mol Pharm. 2017 May 1;14(5):1439-1449
Zhang, W., Müller, K., Kessel, E., Reinhard, S., He, D., Klein, P.M., Höhn, M., Rödl, W., Kempter, S., Wagner, E. (2016) Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nano-Core with an Influenza Peptide and Transferrin Shell, Adv Healthc Mater. 2016 Jun;5(12):1493-504

Liu, X., Zhang, P., He, D., Rödl, W., Preiß, T., Rädler, J., Wagner, E., Lächelt, U. (2016) pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing. Biomacromolecules, 2016, 17 (1):173–182

Zhang, W., Rödl, W., He, D., Döblinger, M., Lächelt, U., Wagner, E. (2015) Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery, J Gene Med. 2015 Aug 9;17(8-9):161-72
Urbiola, K., Blanco-Fernández, L., Navarro, G., Rödl, W., Wagner, E., Ogris, M., Tros de Ilarduya, C. (2015) Evaluation of improved PAMAM-G5 conjugates for gene delivery targeted to the transferrin receptor, Eur J Pharm Biopharm. 2015 Aug;94:116-22

Lächelt, U., Kos, P. Mickler, F.M., Herrmann, A., Salcher, E.E., Rödl, W., Badgujar, N., Bräuchle, C., Wagner, E., (2014) Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes, Nanomedicine. 2014 Jan;10(1):35-44
Rödl, W., Schaffert, D., Wagner, E., Ogris, M. (2013) Synthesis of polyethylenimine based nanocarriers for systemic tumor targeting of nucleic acids, Methods Mol Biol. 2013;948:105-20
Noga, M., Edinger, D., Rödl, W., Wagner, E., Winter, G., Besheer, A. (2012) Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase J control Release. 2012 Jan 16
Abourbeh, G., Shir, A., Mishani, E., Ogris, M., Rödl, W., Wagner, E., Levitzki, A. (2012) PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors IUBMB Life. 2012
Nie, Y., Schaffert, D., Rödl, W., Ogris, M., Wagner, E., Günther, M. (2011) Dual-targeted polyplexes: One step towards a synthetic virus for cancer gene therapy, J Control Release. 2011 May 30;152(1):127-34
Schaffert, D., Kiss, M., Rödl, W., Shir, A., Levitzki, A., Ogris, M., Wagner, E. (2011) Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier, Pharm Res. 2011 Apr;28(4):731-41
Schäfer, A., Pahnke, A., Schaffert, D., van Weerden, W.M., de Ridder, C.M., Rödl, W., Vetter, A., Spitzweg, C., Kraaij, R., Wagner, E., Ogris, M. (2011) Disconnecting the Yin and Yang Relation of Epidermal Growth Factor Receptor (EGFR)-Mediated Delivery: A Fully Synthetic, EGFR-Targeted Gene Transfer System Avoiding Receptor Activation, Hum Gene Ther. 2011 Dec;22(12):1463-73
Shir, A., Ogris, M., Rödl, W., Wagner, E., Levitzki, A. (2011) EGFR-homing dsRNA activates cancer targeted immune response and eliminates disseminated EGFR over-expressing tumors in mice, Clin Cancer Res. 2011 Mar 1;17(5):1033-43
Coulter, J.A., McCarthy, H.O., Xiang, J., Rödl, W., Wagner, E., Robson, T. (2008) Nitric oxide--a novel therapeutic for cancer, Nitric Oxide. 2008 Sep;19(2):192-8
Tietze, N., Pelisek, J., Philipp, A., Rödl, W., Merdan, T., Tarcha, P., Ogris, M., Wagner, E. (2008)Induction of Apoptosis in Murine Neuroblastoma by Systemic Delivery of Transferrin-Shielded siRNA Polyplexes for Downregulation of Ran., Oligonucleotides.2008 Jun;18(2):161-74.
Klöckner, J., Boeckle, S., Klöckner, J., Rödl, W., Ogris, M., Berg, K., Wagner, E. (2006) DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions, J. Control. Rel. 116, 115-122.
Boeckle, S., Fahrmeir, J., Rödl, W., Ogris, M., Wagner, E. (2006) Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes, J. Control. Rel. 112, 240-248.
Smrekar B., Wightman L., Wolschek M.F., Lichtenberger, C., Ruzicka, R., Ogris, M., Rödl, W., Kursa, M., Wagner, E., Kircheis, R. (2003) Tissue-dependent factors affect gene delivery to tumors in vivo, Gene Ther. 10, 1079-1088.
Kursa, M., Walker, G. F., Roessler, V., Ogris, M., Rödl, W., Kircheis, R., Wagner, E. (2003) Novel shielded Transferrin-Polyethylene Glycol-Polyethylenimine / DNA Complexes for Systemic Tumor-Targeted Gene Transfer, Bioconjug. Chem. 14, 222-231.