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Rima Kandil

Rima Kandil, PhD (former PhD Student)


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Thesis Defense: Nov 7, 2019 "T Cell Targeted Nanoparticles for Pulmonary siRNA Delivery as Novel Asthma Therampy"

Jan 2016-July 2019 PhD student, LMU Munich
2015 PhD student, University of Bonn
2015 Board License as Pharmacist
2014 Pharmacy Resident, Merkel Lab, Wayne State University
2013-2014 Pharmacy Resident, Retail Pharmacy
2009 - 2013 Pharmacy School, Rheinische Friedrich-Wilhelms-Universität Bonn, Germany


Rima Kandil, Yuran Xie, Aditi Mehta, Olivia Merkel*: A Method for Targeted Nonviral siRNA Delivery in Cancer and Inflammatory Diseases.Methods Mol Biol. 2020;2059:155-166.

Rima Kandil, Yuran Xie, Ralf Heermann, Lorenz Isert, Kirsten Jung, Aditi Mehta, Olivia M Merkel*: Coming in and Finding Out: Blending Receptor‐Targeted Delivery and Efficient Endosomal Escape in a Novel Bio‐Responsive siRNA Delivery System for Gene Knockdown in Pulmonary T Cells.
Advanced Therapeutics 2019, 2(7). pii: 1900047

Rima Kandil, Olivia M. Merkel, Pulmonary delivery of siRNA as a novel treatment for lung diseases,
Therapeutic Delivery 2019, 10 (4), 203-206.

Rima Kandil, Daniel Feldmann, Yuran Xie, Olivia M. Merkel*: Evaluating the Regulation of Cytokine Levels After siRNA Treatment in Antigen-Specific Target Cell Populations via Intracellular Staining,
Methods in Molecular Biology 2019, 1943, 323-331.

Rima Kandil, Olivia M. Merkel*: Recent Progress of Polymeric Nanogels for Gene Delivery.
Current Opinion in Colloid & Interface Science 2019, 39, 11-23

Daniel P. Feldmann, Ylong Cheng, Rima Kandil, Yuran Xie, Mariam Mohammadi, Hartmann Harz, Akhil Sharma, David J. Peeler, Anna Moszczynska, Heinrich Leonhardt, Suzie H. Pun, Olivia M. Merkel: In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells,
Journal of Controlled Release, 2018, 276:50-58.

Rima Kandil, Jon Felt, Prashant Mahajan, Olivia M. Merkel: The Biology and Clinical Treatment of Asthma,
Nanomedicine for Inflammatory Diseases, 2017, CRC Press, pp.217-244.

Yuran Xie, Rima Kandil, Olivia M. Merkel: Bridging the Gap between the Bench and the Clinic: Asthma,
Nanomedicine for Inflammatory Diseases, 2017, CRC Press, pp.255-286.

Ü Basmanav FB, Cau L, Tafazzoli A, Méchin MC, Wolf S, Romano MT, Valentin F, Wiegmann H, Huchenq A, Kandil R, Garcia Bartels N, Kilic A, George S, Ralser DJ, Bergner S, Ferguson DJP, Oprisoreanu AM, Wehner M, Thiele H, Altmüller J, Nürnberg P, Swan D, Houniet D, Büchner A, Weibel L, Wagner N, Grimalt R, Bygum A, Serre G, Blume-Peytavi U, Sprecher E, Schoch S, Oji V, Hamm H, Farrant P, Simon M, Betz RC: Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome.
Am J Hum Genet. 2016 Dec 1;99(6):1292-1304.

Mariam Mohammadi, Ying Li, Daniel G Abebe, Yuran Xie, Rima Kandil, Teresa Kraus, Nardhy Gomez-Lopez, Tomoko Fujiwara, Olivia M Merkel: Folate receptor targeted three-layered micelles and hydrogels for gene delivery to activated macrophages
Journal of Controlled Release, 2016, doi:10.1016/j.conrel.2016.08.020

Rima Kandil, Olivia M. Merkel: Therapeutic Delivery of siRNA: Diseases affecting the respiratory system,
Die Pharmazie, 2016, 71 (1), 21-26.

Daniel G. Abebe, Rima Kandil, Teresa Kraus, Maha Elsayed, Tomoko Fujiwara, Olivia M. Merkel: Biodegradable Three-Layered Micelles and Injectable Hydrogels,
Methods in Molecular Biology 2016, Non-Viral Gene Delivery Vectors: Methods and Protocols, 1445, 175-185.

Daniel Ghirmay Abebe, Rima Kandil, Teresa Kraus, Maha Elsayed, Olivia M Merkel, Tomoko Fujiwara: Three-Layered Biodegradable Micelles Prepared by Two-Step Self-Assembly of PLA-PEI-PLA and PLA-PEG-PLA Triblock Copolymers as Efficient Gene Delivery System
Macromolecular Bioscience, 2015, 15 (5), 698-717