Mayr's Database Of Reactivity Parameters
AK Prof. Mayr

Details of Molecule Indole

For reactivities of structurally related compounds go to: Nucleophiles » C-Nucleophiles » Arenes » Indoles
Structure image of molecule
Molecule class Nucleophiles » C-Nucleophiles » Arenes » Indoles
Quality ***
Parameters N  Parameter: 5.55
sN Parameter: 1.09
Comment N and sN were determined with reference electrophiles. Preliminary N and (estimated) sN values for indole (5.85/0.80, Chem. Eur. J. 2003, 9, 2209-2218) were rendered more precisely in 2006 after additional measurements with further reference electrophiles.
Sum formula C8H7N
Solvent dichloromethane
Reference J. Org. Chem. 2006, 71, 9088-9095
DOI: 10.1021/jo0614339