Research
Protein Formulation
High concentration antibody formulations incl. suspensions
Protein stabilization
Computer modeling of protein behavior in solution and at interfaces
New surfactants for formulation of biologics
Lyophilization / Frozen Bulk
Process understanding including heat transfer and new characterization tools
Scale down of bulk freezing
Stable lyophilisates of proteins, nanoparticles and ATMPs
Understanding protein and particle behavior in the freeze-concentrate
Protein Aggregation
Driving mechanisms incl. protein-protein-interactions and interface effects
Formulation and mutation / variant effects on aggregation
Protein adsorption to interfaces including air, silicone oil and processing materials
New methods for aggregation analysis