Alumni
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Investigation of molecular environment, mobility, and accessibility in freeze-dried protein formulations and their impact on protein stability by using novel solid-state analytical techniques
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Raman spectroscopy of aggregates and particles in protein pharmaceuticals
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Interfacial aggregation behavior of proteins
2023
Utilizing different PAT tools to improve scale-up and process transfer for freeze drying
2022
Challenges in the development of drug device combination products for biopharmaceuticals
2022
Protein Aggregation Induced by Pumping of Biopharmaceutics
2021
Optimised Freezing and Thawing of Monoclonal Antibody Solutions
2021
Separation and Characterization of Subpopulations of Biopharmaceuticals
2021
Freeze-drying of nanoparticles: Impact of particle properties on formulation and process development
2020
Nests and Chamber Wall Temperature Control as Tools in Pharmaceutical Freeze-Drying – Evaluation of Heat Transfer, Edge-Vial-Effect and Drying Kinetics
2020
Self-Interaction and targeted Engineering of monoclonal Antibodies (2020)
2020
Understanding the Effect of Arginine and the Freeze Concentrate on Antibody Lyophilisates (2020)
2020
Prediction and Characterization of Theraputic Protein Aggregation (2020)
2019
Protein delivery with biocompatible non-aqueous solvents (2019)
2018
Oil-Based Parenteral Depot Formulation for Veterinary Peptide Delivery(2018)
2018
DEVELOPMENT AND CHARACTERIZATION OF IN-VITRO MODELS FOR FILAGGRIN ASSOCIATED SKIN DISEASES (2018)
2018
New aspects of process and formulation development of freeze-drying of proteins (2018)
2018
Studies on the Physicochemical Stability of Antibody conjugates (2018)
2017
Antibody drugs at the liquid-air interface: physicochemical characteristics, aggregation & the impact of formulation (2017)
2017
Sustained release lipid microparticles (2017)
2017
Particle engineering technologies to improve protein drug delivery; spray drying and fluidized bed drying (2017)
2017
Freeze-Drying in Dual Chamber Cartridges - from Energy Transfer to Process Control - (2017)
2016
Cartridges filling with biopharmaceuticals with focus on the optimization of the siliconization process (2016)
2016
Local and targeted delivery of proteins (2016)
2015
Interactions of formulation and disposables in biopharmaceutical drug product manufacturing. (2015)
2014
2014
Formulation development of a highly concentrated suspension of Cilengitide. (2014)
2014
Temperature-Induced Unfolding, Aggregation, and Interaction of Therapeutic Monoclonal Antibodies (2014)
2014
Pharmacokinetic profiling of therapeutic proteins and variants by mass spectrometry (2014)
2014
Investigations on Protein Adsorption to Coated Glass Vials (2014)
2013
Untersuchungen zur Stabilisierung und Interaktion von Cetuximab mit nicht-ionischen Tensiden (2013)
2013
Protein Particle Analysis - Critical Factors and New Standards (2013)
2013
Subcutaneous suspensions of therapeutic proteins formulated as protein-coated microcrystals (2013)
2013
Development of sustained release formulations for the intra-articular delivery of a therapeutic antibody (2013)
2012
Novel Dry Powder Inhalation System Based on Dispersion of Lyophilisates (2012)
2012
Analysis and control of the manufacturing process and the release properties of PLGA microparticles for sustained delivery of a poorly water-soluble drug (2012)
2012
Development of Advanced Biomaterials for Bone Tissue Engineering (2012)
2012
Lyophilization of Nucleic Nanoparticles - Formulation Development, Stabilization Mechanisms, and Process Monitoring (2012)
2011
Sugar-based surfactants for pharmaceutical Protein formulations (2011)
2011
The Value of Fluorescence and B22 Techniques as Complementary Approaches in Protein Stability Analysis (2011)
2011
Spray drying of protein precipitates and Evaluation of the Nano Spray Dryer B-90 (2011)
2010
Protein Adsorption to Vial Surfaces – Quantification, Structural and Mechanistic Studies (2010)
2010
VEGF Carrying Coatings for Enhanced Vascular Graft Endothelialization (2010)
2009
Protein aggregation: Methods, Prediction and Inhibition (2009)
2009
Physical Properties of Protein Formulations (2009)
2008
Infected Biomaterials - New strategies for local anti-infective treatment (2008)
2008
Development of New In-situ Hardening and Bioactivated Composite Materials for Orthopedic Indications (2008)
2007
Ölige Suspensionen als parenterale Depotsysteme für rekombinante Proteine (2007)
2007
Wirbelschichttrocknung von Proteinen (2007)
2006
Studies on Stable Formulations for a Hydrophobic Cytokine (2006)
2006
Development of High Concentration Cetuximab Formulations using Ultrafiltration and Precipitation Techniques (2006)
2005
Stabilization of Antibodies in Spray-dried Powders for Inhalation (2005)
2005
Enzymatic Degradation and Drug Release Behavior of Dense Collagen Implants (2005)
2005
Spray-dried antibody powders for pulmonary application (2005)
2005
Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) (2005)
2003
Chemical and physiochemical stability of spray-dried rhIL-11 formulations
2001
Porous Collagen/Ceramic Composite Carriers for Bone Regeneration Using Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2)
2000
Kollagen/PLGA-Mikropartikel Komposite zur gesteuerten Freigabe von Gentamicin