Mayr's Database of Reactivity Parameters

(S)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(pyrrolidin-2-ylmethyl)thiourea

For reactivities of structurally related compounds go to: Nucleophiles » N-Nucleophiles » Aliphatic amines

Information panel

Name (S)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(pyrrolidin-2-ylmethyl)thiourea
Structure
image of molecule
Molecule class Nucleophiles » N-Nucleophiles » Aliphatic amines
SMILES S=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)NC[C@H]2NCCC2
Molecular formula C14H15F6N3S
Quality ***
Parameters

N  Param.: 14.97

sN Param.: 0.69
Solvent MeCN
Reference J. Am. Chem. Soc. 2020, 142, 1526-1547
10.1021/jacs.9b11877