Mayr's Database of Reactivity Parameters

8-(benzyloxy)-2-phenyl-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxine

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Name 8-(benzyloxy)-2-phenyl-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxine
Structure
Molecule class Nucleophiles » C-Nucleophiles » Enol Ethers » C=C-OR
SMILES [C@@H]1(CO[C@@H](C2=CC=CC=C2)O3)[C@@H]3[C@H](OCC4=CC=CC=C4)C=CO1
Molecular formula C20H20O4
Quality ***
Parameters

N  Param.: 1.94

sN Param.: 1.24
Comment Diarylmethylium (benzhydrylium) and indolyl-aryl-methylium ions were used for the nucleophilicity determination.
Solvent dichloromethane
Reference Angew. Chem. Int. Ed. 2026, EarlyView, e24329
10.1002/anie.202524329