Search
| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
1-phenoxy-1-(trimethylsiloxy)ethene  |
dichloromethane | N Param.: 8.23 sN Param.: 0.81 |  | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
dimethylmethyleneammonium ion |
E Param.: -6.69 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c | |
1,1-bis(trimethylsiloxy)propene |
dichloromethane | N Param.: 10.38 sN Param.: 0.87 | | Eur. J. Org. Chem. 2004, , 2791-2796 10.1002/ejoc.200400134 |
diethyl benzylidene malonate |
E Param.: -20.55 | | Chem. Eur. J. 2008, 14, 9675-9682 10.1002/chem.200801277 | |
3-chloro-benzaldehyde (in DMSO) |
DMSO |  | J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m | |
benzaldehyde-boron trichloride complex |
E Param.: 1.12 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c | |
(5-methyl-furan-2-yl) pinacol boronate |
MeCN | N Param.: 2.90 sN Param.: 0.98 | | Chem. Sci. 2012, 3, 878-882 10.1039/c2sc00883a |
3-(4-methoxybenzylidene)-1-methyl-3H-indol-1-ium iom |
E Param.: -3.02 | | J. Org. Chem. 2015, 80, 8643-8656 10.1021/acs.joc.5b01298 | |
1-(ethoxycarbonyl)-2-oxocycloheptan-1-ide |
DMSO | N Param.: 19.53 sN Param.: 0.83 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
Z-3-(trimethylsiloxy)pent-2-ene |
dichloromethane | N Param.: 5.58 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
Me2S=CH-CO2Et (in DMSO) |
DMSO | N Param.: 15.85 sN Param.: 0.61 | | Chem. Eur. J. 2010, 16, 8610-8614 10.1002/chem.201001455 |
(3-chlorobenzyl)dimethylsilane |
dichloromethane | N Param.: 1.30 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
4,4,5,5-tetramethyl-2-prop-2-enyl-1,3,2-dioxaborolane (in CH2Cl2) |
dichloromethane | N Param.: -0.64 sN Param.: 1.10 | | J. Am. Chem. Soc. 2017, 139, 15324-15327 10.1021/jacs.7b10240 |
(triisopropylsiloxy)ethene |
dichloromethane | N Param.: 3.44 sN Param.: 0.94 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1,3,4-triphenyl-1H-1,2,4-triazol-4-ium-5-ide (in THF) |
THF | N Param.: 14.07 sN Param.: 0.84 | | Angew. Chem. Int. Ed. 2011, 50, 6915-6919 10.1002/anie.201102435 |
acetonitrile (in MeCN) |
MeCN | N Param.: 2.23 sN Param.: 0.84 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
p-(methoxy)benzylidenemalononitrile |
E Param.: -10.80 | | J. Org. Chem. 2003, 68, 6880-6886 10.1021/jo0344182 | |
2-phenyl-1,3-dithiolan-2-ylium ion |
E Param.: -5.91 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c | |
anion of (4-cyanophenyl)nitromethane (in water) |
water | N Param.: 13.23 sN Param.: 0.52 | | J. Org. Chem. 2004, 69, 7565-7576 10.1021/jo048773j |
di-p-tolyl-allylium ion |
E Param.: 1.23 | | J. Org. Chem. 2011, 76, 9391-9408 10.1021/jo201668w |
News
- 01/30/25:
Sesamol-derived ortho-quinone methides (o-QM) have been added (ChemEurJ 2024, e202403785 & OBC 2025, 23, 827-834) - 05/22/24:
Lactone enolates have been added (JOC 2024, 89, 6915-6928). - 11/13/24:
2-Methylene-1,2-dihydropyridines (2-pyNHOs) have been added (EurJOC 2024, 27, e202400373). - 05/21/24:
Mesoionic pyridinium-derived N-heterocyclic olefins (py-mNHOs) have been added (Angew. Chem. Int. Ed. 2024, 63, e202318283). - 10/19/23:
Enamines derived from 4-(alkylthio)-3-imidazolines and aldehydes have been added (ChemEurJ 2023, doi: 10.1002/chem.202302764). - 09/28/23:
Mesoionic N-heterocyclic olefins (mNHOs) have been added (Angew. Chem. Int. Ed. 2023, 62, e202309790). - 07/05/23:
S-Cyanomethylated imidazolidine-4-thione-derived enamines have been added (ChemComm 2023, 59, 8091). - 03/16/23:
Cyclic alpha-diazo carbonyl compounds added (EurJOC 2023, 26, e202300005) - 01/30/23:
NADH and NADPH reactivities (in water, pH 7) determined by Mayer and Moran have been added (OBC 2022, 21, 85-88). - 09/20/22:
Alkenyl boronate nucleophilicity by Liu, Ready and co-workers has been added (JACS 2022, 144, 16118). - 01/30/23:
Electrophilicities of diazo compounds in azo couplings (ChemEurJ 2022, 28, e202201376) - 01/30/23:
Diazocyclopentadiene added (Synthesis 2023, 55, 354-358) - 01/30/23:
Electrophilic indoles added (ChemCommun 2021, 57, 10071-10074) - 04/13/21:
Cyclic Michael acceptors added (Chem. Sci. 2021, 12, 4850-4865) - 05/21/21:
Thiophenolates (in DMSO) added (JOC 2021, 86, 5965-5972) - 05/06/20:
Heteroallenes added (JACS 2020, 142, 8383-8402). - 01/27/20:
Pyrrolidines and Imidazolidinones added (JACS 2020, 142, 1526-1547). - 05/06/20:
GSH reactivity added (Angew. Chem. Int. Ed. 2019, 58, 17704-17708) - 01/30/23:
Phenolates added (JOC 2019, 84, 8837-8858) - 04/24/18:
Ketones added (JACS 2018, 140, 5500). - 11/03/17:
Allyl-boron nucleophiles added (JACS 2017, 139, 15324) - 04/23/18:
Peroxide anions added (Angew. Chem. Int. Ed. 2017, 56, 13279). - 04/23/18:
Michael acceptors added (JACS 2017, 139, 13318). - 06/16/17:
Nucleophilicities of VNS reagents (JOC 2017, 82, 1011).