Search
| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
(E)-6-(4-methylbenzylidene)benzo[d][1,3]dioxol-5(6H)-one  |
E Param.: -14.85 |  | Chem. Eur. J. 2025, 31, e202403785 10.1002/chem.202403785 | |
(E)-6-(4-nitrobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
E Param.: -13.15 | | Chem. Eur. J. 2025, 31, e202403785 10.1002/chem.202403785 | |
(E)-6-(furan-2-ylmethylene)benzo[d][1,3]dioxol-5(6H)-one |
E Param.: -15.73 | | Org. Biomol. Chem. 2025, 23, 827-834 10.1039/D4OB01855A | |
(E)-6-benzylidenebenzo[d][1,3]dioxol-5(6H)-one |
E Param.: -14.47 | | Chem. Eur. J. 2025, 31, e202403785 10.1002/chem.202403785 | |
(E)-beta-(N-morpholino)styrene |
dichloromethane | N Param.: 10.76 sN Param.: 0.87 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
(E)-beta-(N-piperidino)styrene (in MeCN) |
MeCN | N Param.: 13.84 sN Param.: 0.73 | | Chem. Eur. J. 2018, 24, 5901-5910 10.1002/chem.201705962 |
(E)-but-2-ene |
dichloromethane | N Param.: -2.45 sN Param.: 1.10 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
(E)-but-2-enyltrimethylsilane |
dichloromethane | N Param.: 1.94 sN Param.: 1.10 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
(E)-N-(4-(dimethylamino)benzylidene)-4-methylbenzenesulfonamide (in DMSO) |
DMSO | E Param.: -15.09 | | J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide (in DMSO) |
DMSO | E Param.: -13.05 | | J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-N-benzylidene-4-methylbenzenesulfonamide (in DMSO) |
DMSO | E Param.: -11.50 | | J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-N-benzylidene-P,P-diphenylphosphinic amide |
DMSO | E Param.: -15.89 | | J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-penta-1,3-diene |
dichloromethane | N Param.: 1.49 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
(E)-propenylbenzene |
dichloromethane | N Param.: -0.49 sN Param.: 1.18 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
(E)-tert-butyl benzylidenecarbamate (in DMSO) |
DMSO | E Param.: -14.22 | | J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E,E)-2,5-heptadiene |
dichloromethane | N Param.: -0.74 sN Param.: 0.99 | | J. Am. Chem. Soc. 2002, 124, 4076-4083 10.1021/ja0121538 |
(E,E)-hexa-2,4-diene |
dichloromethane | N Param.: 1.17 sN Param.: 1.10 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
(ethene-1,1-diyldisulfonyl)dibenzene |
DMSO | E Param.: -7.50 | | Chem. Asian J. 2012, 7, 1401-1407 10.1002/asia.201101046 |
(EtO)2P(O)CH(-)CN (in DMSO) |
DMSO | N Param.: 18.57 sN Param.: 0.66 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
(EtO)2P(O)CH(-)CO2Et (in DMSO) |
DMSO | N Param.: 19.23 sN Param.: 0.65 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
News
- 01/30/25:
Sesamol-derived ortho-quinone methides (o-QM) have been added (ChemEurJ 2024, e202403785 & OBC 2025, 23, 827-834) - 05/22/24:
Lactone enolates have been added (JOC 2024, 89, 6915-6928). - 11/13/24:
2-Methylene-1,2-dihydropyridines (2-pyNHOs) have been added (EurJOC 2024, 27, e202400373). - 05/21/24:
Mesoionic pyridinium-derived N-heterocyclic olefins (py-mNHOs) have been added (Angew. Chem. Int. Ed. 2024, 63, e202318283). - 10/19/23:
Enamines derived from 4-(alkylthio)-3-imidazolines and aldehydes have been added (ChemEurJ 2023, doi: 10.1002/chem.202302764). - 09/28/23:
Mesoionic N-heterocyclic olefins (mNHOs) have been added (Angew. Chem. Int. Ed. 2023, 62, e202309790). - 07/05/23:
S-Cyanomethylated imidazolidine-4-thione-derived enamines have been added (ChemComm 2023, 59, 8091). - 03/16/23:
Cyclic alpha-diazo carbonyl compounds added (EurJOC 2023, 26, e202300005) - 01/30/23:
NADH and NADPH reactivities (in water, pH 7) determined by Mayer and Moran have been added (OBC 2022, 21, 85-88). - 09/20/22:
Alkenyl boronate nucleophilicity by Liu, Ready and co-workers has been added (JACS 2022, 144, 16118). - 01/30/23:
Electrophilicities of diazo compounds in azo couplings (ChemEurJ 2022, 28, e202201376) - 01/30/23:
Diazocyclopentadiene added (Synthesis 2023, 55, 354-358) - 01/30/23:
Electrophilic indoles added (ChemCommun 2021, 57, 10071-10074) - 04/13/21:
Cyclic Michael acceptors added (Chem. Sci. 2021, 12, 4850-4865) - 05/21/21:
Thiophenolates (in DMSO) added (JOC 2021, 86, 5965-5972) - 05/06/20:
Heteroallenes added (JACS 2020, 142, 8383-8402). - 01/27/20:
Pyrrolidines and Imidazolidinones added (JACS 2020, 142, 1526-1547). - 05/06/20:
GSH reactivity added (Angew. Chem. Int. Ed. 2019, 58, 17704-17708) - 01/30/23:
Phenolates added (JOC 2019, 84, 8837-8858) - 04/24/18:
Ketones added (JACS 2018, 140, 5500). - 11/03/17:
Allyl-boron nucleophiles added (JACS 2017, 139, 15324) - 04/23/18:
Peroxide anions added (Angew. Chem. Int. Ed. 2017, 56, 13279). - 04/23/18:
Michael acceptors added (JACS 2017, 139, 13318). - 06/16/17:
Nucleophilicities of VNS reagents (JOC 2017, 82, 1011).