Mayr's Database Of Reactivity Parameters
AK Prof. Mayr

Pyridines, Quinolines etc.

For reactivities of structurally related compounds go to: Nucleophiles » N-Nucleophiles
Found 48 Molecules.
Molecule Solvent Reactivity Parameters Classification Reference (sort by title or year)
image of molecule

pyridine (in MeCN)
MeCNN  Parameter: 13.60
sN Parameter: 0.60
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
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2-methylpyridine (in CH2Cl2)
dichloromethaneN  Parameter: 10.52
sN Parameter: 0.78
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
image of molecule

2-methylpyridine (in MeCN)
MeCNN  Parameter: 10.98
sN Parameter: 0.66
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
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2,6-dimethylpyridine (in CH2Cl2)
dichloromethaneN  Parameter: 9.87
sN Parameter: 0.68
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
image of molecule

2,6-dimethylpyridine (in MeCN)
MeCNN  Parameter: 9.11
sN Parameter: 0.69
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
image of molecule

2,4,6-trimethylpyridine (in CH2Cl2)
dichloromethaneN  Parameter: 9.34
sN Parameter: 0.71
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
image of molecule

2,4,6-trimethylpyridine (in MeCN)
MeCNN  Parameter: 9.39
sN Parameter: 0.60
***Synthesis 2017, 49, 3495-3504
DOI: 10.1055/s-0036-1590504
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nicotine (in CH2Cl2)
dichloromethaneN  Parameter: 10.40
sN Parameter: 1.04
***J. Phys. Org. Chem. 2016, 29, 759-767
DOI: 10.1002/poc.3580
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nicotine (in MeCN)
MeCNN  Parameter: 11.60
sN Parameter: 0.81
***J. Phys. Org. Chem. 2016, 29, 759-767
DOI: 10.1002/poc.3580
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3-methylpyridine (in CH2Cl2)
dichloromethaneN  Parameter: 10.90
sN Parameter: 0.93
***J. Phys. Org. Chem. 2016, 29, 759-767
DOI: 10.1002/poc.3580
image of molecule

3-methylpyridine (in MeCN)
MeCNN  Parameter: 11.50
sN Parameter: 0.80
***J. Phys. Org. Chem. 2016, 29, 759-767
DOI: 10.1002/poc.3580
image of molecule

4-(morpholino)pyridine (in CH2Cl2)
dichloromethaneN  Parameter: 14.59
sN Parameter: 0.69
***Eur. J. Org. Chem. 2016, , 4050-4058
DOI: 10.1002/ejoc.201600572
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4-(2-(fluorodiphenylmethyl)pyrrolidin-1-yl)pyridine
dichloromethaneN  Parameter: 14.57
sN Parameter: 0.75
***Eur. J. Org. Chem. 2014, , 1202-1211
DOI: 10.1002/ejoc.201301730
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TCAP (in MeCN)
MeCNN  Parameter: 15.60
sN Parameter: 0.68
***Chem. Eur. J. 2013, 19, 6435-6442
DOI: 10.1002/chem.201204452
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4-pyrrolidinopyridine (in MeCN)
MeCNN  Parameter: 14.99
sN Parameter: 0.69
***Chem. Eur. J. 2013, 19, 6435-6442
DOI: 10.1002/chem.201204452
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4-(dimethylamino)pyridine (in MeCN)
MeCNN  Parameter: 15.51
sN Parameter: 0.62
***J. Phys. Chem. A 2012, 116, 8494-8499
DOI: 10.1021/jp3049247
image of molecule

4-(morpholino)pyridine (in MeCN)
MeCNN  Parameter: 14.80
sN Parameter: 0.63
***J. Phys. Chem. A 2012, 116, 8494-8499
DOI: 10.1021/jp3049247
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3-bromo-4-(dimethylamino)pyridine (in MeCN)
MeCNN  Parameter: 12.96
sN Parameter: 0.67
***J. Phys. Chem. A 2012, 116, 8494-8499
DOI: 10.1021/jp3049247
image of molecule

4-amino-3,5-dibromo-pyridine (in MeCN)
MeCNN  Parameter: 11.11
sN Parameter: 0.75
***J. Phys. Chem. A 2012, 116, 8494-8499
DOI: 10.1021/jp3049247
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4-acetamido-pyridine (in MeCN)
MeCNN  Parameter: 13.24
sN Parameter: 0.67
***J. Phys. Chem. A 2012, 116, 8494-8499
DOI: 10.1021/jp3049247
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2-Me super-dmap (in MeCN)
MeCNN  Parameter: 16.65
sN Parameter: 0.58
***Org. Lett. 2011, 13, 530-533
DOI: 10.1021/ol1029589
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2-Et super-dmap (in MeCN)
MeCNN  Parameter: 16.81
sN Parameter: 0.60
***Org. Lett. 2011, 13, 530-533
DOI: 10.1021/ol1029589
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2-Bn super-dmap (in MeCN)
MeCNN  Parameter: 17.69
sN Parameter: 0.57
***Org. Lett. 2011, 13, 530-533
DOI: 10.1021/ol1029589
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2-Ac super-dmap (in MeCN)
MeCNN  Parameter: 15.39
sN Parameter: 0.60
***Org. Lett. 2011, 13, 530-533
DOI: 10.1021/ol1029589
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2-Bz super-dmap (in MeCN)
MeCNN  Parameter: 14.19
sN Parameter: 0.67
***Org. Lett. 2011, 13, 530-533
DOI: 10.1021/ol1029589
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4-(dimethylamino)pyridine (in THF)
THFN  Parameter: 15.90
sN Parameter: 0.66
***Angew. Chem. Int. Ed. 2011, 50, 6915-6919
DOI: 10.1002/anie.201102435
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6-methoxy-quinoline (in MeCN)
MeCNN  Parameter: 10.86
sN Parameter: 0.66
***J. Org. Chem. 2009, 74, 7157-7164
DOI: 10.1021/jo901670w
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4-methyl-quinoline alias lepidine (in MeCN)
MeCNN  Parameter: 11.60
sN Parameter: 0.62
***J. Org. Chem. 2009, 74, 7157-7164
DOI: 10.1021/jo901670w
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2-(naphthylmethyl)quinuclidine (in MeCN)
MeCNN  Parameter: 15.66
sN Parameter: 0.62
***J. Org. Chem. 2009, 74, 7157-7164
DOI: 10.1021/jo901670w
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quinine
dichloromethaneN  Parameter: 10.46
sN Parameter: 0.75
***J. Org. Chem. 2009, 74, 7157-7164
DOI: 10.1021/jo901670w
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quinidine
dichloromethaneN  Parameter: 10.54
sN Parameter: 0.74
***J. Org. Chem. 2009, 74, 7157-7164
DOI: 10.1021/jo901670w
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4-chloropyridine (in CH2Cl2)
dichloromethaneN  Parameter: 11.70
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
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4-chloropyridine (in H2O)
waterN  Parameter: 10.50
sN Parameter: 0.73
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
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pyridine (in CH2Cl2)
dichloromethaneN  Parameter: 12.90
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

pyridine (in H2O)
waterN  Parameter: 11.05
sN Parameter: 0.73
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-methylpyridine (in CH2Cl2)
dichloromethaneN  Parameter: 13.70
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-methylpyridine (in H2O)
waterN  Parameter: 11.10
sN Parameter: 0.75
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-methoxypyridine (in CH2Cl2)
dichloromethaneN  Parameter: 13.70
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-methoxypyridine (in H2O)
waterN  Parameter: 11.44
sN Parameter: 0.68
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-aminopyridine (in CH2Cl2)
dichloromethaneN  Parameter: 15.20
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-aminopyridine (in H2O)
waterN  Parameter: 12.19
sN Parameter: 0.66
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-(dimethylamino)pyridine (in CH2Cl2)
dichloromethaneN  Parameter: 15.80
sN Parameter: 0.66
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-(dimethylamino)pyridine (in H2O)
waterN  Parameter: 13.19
sN Parameter: 0.56
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-(dimethylamino)pyridine (in 91M9AN)
MeOH-MeCN mixN  Parameter: 13.20
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
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4-(dimethylamino)pyridine (in DMSO)
DMSON  Parameter: 14.80
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-(dimethylamino)pyridine (in DMF)
DMFN  Parameter: 14.90
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-pyrrolidinopyridine (in CH2Cl2)
dichloromethaneN  Parameter: 15.90
sN Parameter: 0.67
*Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941
image of molecule

4-pyrrolidinopyridine (in H2O)
waterN  Parameter: 12.39
sN Parameter: 0.66
***Chem. Eur. J. 2007, 13, 336-345
DOI: 10.1002/chem.200600941