Mayr's Database of Reactivity Parameters

Nucleophiles

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Name Solvent Reactivity
Parameters
Classification Reference
(title or year)
anion of ethyl cyanoacetate (in 91M9AN)
C5H6NO2- *
MeOH-MeCN mix

N  Param.: 18.59

sN Param.: 0.65
*** Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of malononitrile (in 91M9AN)
C3HN2- *
MeOH-MeCN mix

N  Param.: 18.21

sN Param.: 0.69
*** Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of dimethyl malonate (in 91M9AN)
C5H7O4- *
MeOH-MeCN mix

N  Param.: 18.24

sN Param.: 0.64
*** Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
azide ion (in 91M9AN)
N3- *
MeOH-MeCN mix

N  Param.: 14.54

sN Param.: 0.82
*** J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 91E9AN)
N3- *
EtOH-MeCN mix

N  Param.: 16.30

sN Param.: 0.73
*** J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 91nPr9AN)
N3- *
nPrOH-MeCN mix

N  Param.: 16.70

sN Param.: 0.73
*** J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 91iPr9AN)
N3- *
iPrOH-MeCN mix

N  Param.: 17.07

sN Param.: 0.71
*** J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in DMSO)
N3- *
DMSO

N  Param.: 20.50

sN Param.: 0.59
*** J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 45M55AN)
N3- *
MeOH-MeCN mix

N  Param.: 15.01

sN Param.: 0.80
*** J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
pyrrolidine (in 91M9AN)
C4H9N *
MeOH-MeCN mix

N  Param.: 15.97

sN Param.: 0.63
*** Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542