Mayr's Database of Reactivity Parameters

Nucleophiles

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Name Solvent Reactivity
Parameters
Classification Reference
(title or year)
3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-methylenetetrahydro-2H-pyran
C35H36O5*
dichloromethane

N  Param.: 4.01

sN Param.: 0.91
***Angew. Chem. Int. Ed. 2026, EarlyView, e24329
10.1002/anie.202524329
3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-5-methylenetetrahydrofuran
C27H28O4*
dichloromethane

N  Param.: 5.50

sN Param.: 0.76
***Angew. Chem. Int. Ed. 2026, EarlyView, e24329
10.1002/anie.202524329
4-((benzyloxy)methyl)-2,2-dimethyl-6-methylenetetrahydrofuro[3,4-d][1,3]dioxole
C16H20O4*
dichloromethane

N  Param.: 5.35

sN Param.: 0.88
***Angew. Chem. Int. Ed. 2026, EarlyView, e24329
10.1002/anie.202524329
8-(benzyloxy)-2-phenyl-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxine
C20H20O4*
dichloromethane

N  Param.: 1.94

sN Param.: 1.24
***Angew. Chem. Int. Ed. 2026, EarlyView, e24329
10.1002/anie.202524329
3,4-bis(benzyloxy)-2-methyl-3,4-dihydro-2H-pyran
 C20H22O3*
dichloromethane

N  Param.: 2.04

sN Param.: 1.20
***Angew. Chem. Int. Ed. 2026, EarlyView, e24329
10.1002/anie.202524329
phosphaethynolate ion (in MeCN)
COP-*
MeCN

N  Param.: 19.02

sN Param.: 0.82
***Chem. Sci. 2024, 15, 14406-14414
10.1039/D4SC03518F
2-(1-azidovinyl)naphthalene (in Cyrene)
C12H9N3*
Cyrene (TM)

N  Param.: 6.00

sN Param.: 0.90
***Chem. Commun. 2026, 62, 5041-5045
10.1039/d6cc00190d