Nucleophiles
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« Back Forward » Found 1325 molecules, displaying page 10 of 14 Results per page
10|50|100|all
| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
67% methanol/33% MeCN (v/v)  |
MeOH-MeCN mix | N Param.: 7.01 sN Param.: 0.91 |  | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
1,1-dimethyl-2-methylenehydrazine (in CH2Cl2) |
dichloromethane | N Param.: 6.98 sN Param.: 0.85 | | Angew. Chem. Int. Ed. 2013, 52, 11900-11904 10.1002/anie.201305092 |
lithium (5-methylthiophen-2-yl)(4-methylphenyl)pinacolborate |
MeCN | N Param.: 6.98 sN Param.: 0.93 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
80% ethanol/20% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 6.94 sN Param.: 0.90 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
2-methylindole |
MeCN | N Param.: 6.91 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
Dimethyl bis(indenyl)zirconium(IV) |
dichloromethane | N Param.: 6.89 sN Param.: 1.00 | | Chem. Eur. J. 2016, 22, 11196-11200 10.1002/chem.201602452 |
methanol (in MeCN) |
MeCN | N Param.: 6.86 sN Param.: 0.73 | | Bull. Chem. Soc. Jpn. 2018, 91, 523-530 10.1246/bcsj.20170360 |
potassium trifluoro(furan-3-yl)borate |
MeCN | N Param.: 6.83 sN Param.: 0.93 | | J. Am. Chem. Soc. 2013, 135, 6317-6324 10.1021/ja4017655 |
isopropanol (in MeCN) |
MeCN | N Param.: 6.82 sN Param.: 0.70 | | Bull. Chem. Soc. Jpn. 2018, 91, 523-530 10.1246/bcsj.20170360 |
(allyl)dicarbonyl(cyclopentadienyl)iron(II) |
dichloromethane | N Param.: 6.78 sN Param.: 0.95 | | Helv. Chim. Acta 2005, 88, 1754-1768 10.1002/hlca.200590137 |
1-(trimethylsiloxy)cyclooctene |
dichloromethane | N Param.: 6.77 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
lithium (5-methylthiophen-2-yl)(4-chlorophenyl)pinacolborate |
MeCN | N Param.: 6.77 sN Param.: 0.88 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
67% ethanol/33% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 6.74 sN Param.: 0.89 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
6-(4-dimethylamino-phenyl)fulvene |
MeCN | N Param.: 6.72 sN Param.: 0.87 | | Eur. J. Org. Chem. 2009, , 1202-1206 10.1002/ejoc.200801099 |
20% water/80%EtOH (v/v) |
water-EtOH mix | N Param.: 6.68 sN Param.: 0.85 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
(1H-inden-1-yl)trimethylstannane (in CH2Cl2) |
dichloromethane | N Param.: 6.68 sN Param.: 0.81 | | Angew. Chem. Int. Ed. 2015, 54, 12497-12500 10.1002/anie.201501385 |
50% methanol/50% MeCN (v/v) |
MeOH-MeCN mix | N Param.: 6.67 sN Param.: 0.90 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
azulene |
MeCN | N Param.: 6.66 sN Param.: 1.02 | | Eur. J. Org. Chem. 2009, , 1202-1206 10.1002/ejoc.200801099 |
lithium 2-isopropyl-4,4,5,5-tetramethyl-2-(4-(trifluoromethyl)phenyl)-1,3,2-dioxaborolan-2-uide (in MeCN) |
MeCN | N Param.: 6.63 sN Param.: 0.75 | | Org. Lett. 2015, 17, 2614-2617 10.1021/acs.orglett.[...] |
1-(trimethylsiloxy)cycloheptene |
dichloromethane | N Param.: 6.62 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
trans-HMo(CO)2(PPh3)Cp |
dichloromethane | N Param.: 6.60 sN Param.: 0.80 |  | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1-(trimethylsiloxy)cyclopentene |
dichloromethane | N Param.: 6.57 sN Param.: 0.93 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
N-(1-(p-tolyl)vinyl)acetamide |
MeCN | N Param.: 6.57 sN Param.: 0.91 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
1,2-dimethylindole |
dichloromethane | N Param.: 6.54 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
dimethyl((trimethylstannyl)methyl)silane |
dichloromethane | N Param.: 6.53 sN Param.: 0.58 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
| trans-HMo(CO)2(PCy3)Cp |
dichloromethane | N Param.: 6.50 sN Param.: 0.80 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
lithium (5-methylthiophen-2-yl)(4-(trifluoromethyl)phenyl)catecholglycolborate |
MeCN | N Param.: 6.50 sN Param.: 0.77 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
91% propan-2-ol/9% MeCN (v/v) |
iPrOH-MeCN mix | N Param.: 6.49 sN Param.: 0.96 | | Can. J. Chem. 2005, 83, 1554-1560 10.1139%2Fv05-170 |
(E)-2,2,3,5,5-pentamethyl-1-styrylimidazolidine-4-thione (in MeCN) |
MeCN | N Param.: 6.49 sN Param.: 0.83 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
potassium (1-(tert-butoxycarbonyl)-1H-indol-2-yl)trifluoroborate |
MeCN | N Param.: 6.46 sN Param.: 0.96 | | J. Am. Chem. Soc. 2013, 135, 6317-6324 10.1021/ja4017655 |
5-hydroxy-indole |
MeCN | N Param.: 6.44 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
1-(trimethylsiloxy)cyclopentene (in MeCN) |
MeCN | N Param.: 6.43 sN Param.: 0.89 | | Chem. Asian J. 2012, 7, 1401-1407 10.1002/asia.201101046 |
33% methanol/67% MeCN (v/v) |
MeOH-MeCN mix | N Param.: 6.38 sN Param.: 0.92 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
(5-methyl-furan-2-yl) MDA boronate |
MeCN | N Param.: 6.38 sN Param.: 0.86 | | Chem. Sci. 2012, 3, 878-882 10.1039/c2sc00883a |
50% ethanol/50% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 6.37 sN Param.: 0.90 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
lithium 2-benzyl-2-(3,5-bis(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-uide (in MeCN) |
MeCN | N Param.: 6.30 sN Param.: 0.78 | | Org. Lett. 2015, 17, 2614-2617 10.1021/acs.orglett.[...] |
40% water/60%EtOH (v/v) |
water-EtOH mix | N Param.: 6.28 sN Param.: 0.87 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
N-(1-(naphthalen-2-yl)vinyl)acetamide |
MeCN | N Param.: 6.28 sN Param.: 0.95 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
lithium (5-methylthiophen-2-yl)(4-(trifluoromethyl)phenyl)pinacolborate |
MeCN | N Param.: 6.24 sN Param.: 1.00 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
1-phenyl-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 6.22 sN Param.: 0.96 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
5-methoxy-indole |
dichloromethane | N Param.: 6.22 sN Param.: 1.12 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
benzyl (1-phenylvinyl)carbamate |
MeCN | N Param.: 6.21 sN Param.: 0.87 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
5-(4-(methoxy)benzyl)-2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ide |
MeCN | N Param.: 6.21 sN Param.: 0.68 | | Chem. Eur. J. 2014, 20, 11069-11077 10.1002/chem.201403161 |
Dimedone iodonium ylide (in CH2Cl2) |
dichloromethane | N Param.: 6.18 sN Param.: 0.81 | | J. Am. Chem. Soc. 2016, 138, 10304-10313 10.1021/jacs.6b05768 |
5-chloro-2-methylindole |
MeCN | N Param.: 6.08 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
33% ethanol/67% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 6.06 sN Param.: 0.90 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
20% methanol/80% MeCN (v/v) |
MeOH-MeCN mix | N Param.: 6.04 sN Param.: 0.94 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
2-(tris(trimethylsilyl)siloxy)propene |
dichloromethane | N Param.: 6.04 sN Param.: 0.82 | | Org. Lett. 2010, 12, 5206-5209 10.1021/ol102220e |
(S)-5-benzyl-2,2,3-trimethylimidazolidin-4-one |
MeCN | N Param.: 6.04 sN Param.: 0.92 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
5-methyl-indole |
MeCN | N Param.: 6.00 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
potassium trifluoro(furan-2-yl)borate |
MeCN | N Param.: 5.99 sN Param.: 0.79 | | J. Am. Chem. Soc. 2013, 135, 6317-6324 10.1021/ja4017655 |
50% water/50%EtOH (v/v) |
water-EtOH mix | N Param.: 5.96 sN Param.: 0.89 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
tributylgermane |
dichloromethane | N Param.: 5.92 sN Param.: 0.73 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
N-methylpyrrole |
dichloromethane | N Param.: 5.85 sN Param.: 1.03 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
60% water/40%EtOH (v/v) |
water-EtOH mix | N Param.: 5.81 sN Param.: 0.90 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
(2S,5S)-5-benzyl-2-(tert-butyl)-3-methyl-1-((E)-styryl)imidazolidin-4-one |
MeCN | N Param.: 5.80 sN Param.: 0.87 | | Angew. Chem. Int. Ed. 2012, 51, 5739-5742 10.1002/anie.201201240 |
water (in MeCN) |
MeCN | N Param.: 5.79 sN Param.: 0.72 | | Bull. Chem. Soc. Jpn. 2018, 91, 523-530 10.1246/bcsj.20170360 |
20% water/80% acetone (v/v) |
water-acetone mix | N Param.: 5.77 sN Param.: 0.87 | | Angew. Chem. Int. Ed. 2004, 43, 2302-2305 10.1002/anie.200353468 |
20% ethanol/80% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 5.77 sN Param.: 0.92 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
1-(triphenylsiloxy)cyclopentene |
dichloromethane | N Param.: 5.76 sN Param.: 1.02 | | Eur. J. Org. Chem. 2005, , 1760-1764 10.1002/ejoc.200400706 |
N-methylindole |
dichloromethane | N Param.: 5.75 sN Param.: 1.23 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
N-(1-phenylvinyl)acetamide |
MeCN | N Param.: 5.73 sN Param.: 0.97 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
10% water/90% acetone (v/v) |
water-acetone mix | N Param.: 5.70 sN Param.: 0.85 | | Angew. Chem. Int. Ed. 2004, 43, 2302-2305 10.1002/anie.200353468 |
triphenylstannane |
dichloromethane | N Param.: 5.64 sN Param.: 0.59 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
N-(cyclohex-1-en-1-yl)acetamide |
MeCN | N Param.: 5.64 sN Param.: 0.79 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
2-diazoindan-1-one |
dichloromethane | N Param.: 5.61 sN Param.: 0.65 | | Eur. J. Org. Chem. 2023, 26, e202300005 10.1002/ejoc.202300005 |
N-(1-(4-chlorophenyl)vinyl)acetamide |
MeCN | N Param.: 5.60 sN Param.: 1.00 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
Z-3-(trimethylsiloxy)pent-2-ene |
dichloromethane | N Param.: 5.58 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
2-(tert.butyldimethylsiloxy)propene |
dichloromethane | N Param.: 5.58 sN Param.: 0.90 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
Indole |
dichloromethane | N Param.: 5.55 sN Param.: 1.09 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
10% methanol/90% MeCN (v/v) |
MeOH-MeCN mix | N Param.: 5.55 sN Param.: 0.97 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
80% water/20%EtOH (v/v) |
water-EtOH mix | N Param.: 5.54 sN Param.: 0.94 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
10-methyl-9,10-dihydroacridine |
dichloromethane | N Param.: 5.54 sN Param.: 0.90 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
lithium (5-methylthiophen-2-yl)(3,5-bis(trifluoromethyl)phenyl)pinacolborate |
MeCN | N Param.: 5.53 sN Param.: 1.00 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
triphenyl phosphite |
dichloromethane | N Param.: 5.51 sN Param.: 0.76 | | Chem. Eur. J. 2005, 11, 917-927 10.1002/chem.200400696 |
5-benzyl-2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ide |
MeCN | N Param.: 5.51 sN Param.: 0.70 | | Chem. Eur. J. 2014, 20, 11069-11077 10.1002/chem.201403161 |
(Cp*)2Zr(Me)2 - Dimethyl-bis(pentamethylcyclopentadienyl)zirconium |
dichloromethane | N Param.: 5.49 sN Param.: 1.06 | | Chem. Eur. J. 2016, 22, 11196-11200 10.1002/chem.201602452 |
tert-butyl isocyanide |
dichloromethane | N Param.: 5.47 sN Param.: 0.77 | | Angew. Chem. Int. Ed. 2007, 46, 3563-3566 10.1002/anie.200605205 |
allyltributylstannane |
dichloromethane | N Param.: 5.46 sN Param.: 0.89 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
N-(1-phenylvinyl)benzamide |
MeCN | N Param.: 5.44 sN Param.: 1.00 | | Chem. Eur. J. 2012, 18, 5732-5740 10.1002/chem.201103519 |
(2S,5S)-5-benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one |
MeCN | N Param.: 5.44 sN Param.: 1.12 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
2-(trimethylsiloxy)propene |
dichloromethane | N Param.: 5.41 sN Param.: 0.91 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
4-methoxy-indole |
MeCN | N Param.: 5.41 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
3-methyl-2-(trimethylsiloxy)but-1-ene |
dichloromethane | N Param.: 5.41 sN Param.: 0.90 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
2-(triisopropylsiloxy)propene |
dichloromethane | N Param.: 5.38 sN Param.: 0.85 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
90% water/10%EtOH (v/v) |
water-EtOH mix | N Param.: 5.38 sN Param.: 0.91 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
2-phenyl-allyltrimethylsilane |
dichloromethane | N Param.: 5.38 sN Param.: 0.89 | | Chem. Eur. J. 2014, 20, 1103-1110 10.1002/chem.201303215 |
dimethyl((trimethylgermyl)methyl)silane |
dichloromethane | N Param.: 5.36 sN Param.: 0.62 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
tert-butanol (in MeCN) |
MeCN | N Param.: 5.35 sN Param.: 0.72 | | Bull. Chem. Soc. Jpn. 2018, 91, 523-530 10.1246/bcsj.20170360 |
diphenyldiazomethane |
dichloromethane | N Param.: 5.29 sN Param.: 0.92 | | Chem. Eur. J. 2003, 9, 4068-4076 10.1002/chem.200304913 |
potassium allyltrifluoroborate (in MeCN) |
MeCN | N Param.: 5.29 sN Param.: 0.87 | | J. Am. Chem. Soc. 2017, 139, 15324-15327 10.1021/jacs.7b10240 |
1-(trimethylsiloxy)cyclohexene |
dichloromethane | N Param.: 5.21 sN Param.: 1.00 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
H2O (in water) |
water | N Param.: 5.20 sN Param.: 0.89 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
| HOs(CO)2Cp* |
dichloromethane | N Param.: 5.20 sN Param.: 0.95 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
Dimethyl 1,1'-isopropylidenezirconocene |
dichloromethane | N Param.: 5.20 sN Param.: 1.00 | | Chem. Eur. J. 2016, 22, 11196-11200 10.1002/chem.201602452 |
10% ethanol/90% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 5.19 sN Param.: 0.96 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
(Z)-1-phenyl-1-(trimethylsiloxy)propene (in MeCN) |
MeCN | N Param.: 5.18 sN Param.: 0.94 | | Synthesis 2019, 51, 1157-1170 10.1055/s-0037-1611634 |
91% water/9% MeCN (v/v) |
water-MeCN mix | N Param.: 5.16 sN Param.: 0.91 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
N-benzyl-N-(but-1-yn-1-yl)-4-methylbenzenesulfonamide |
dichloromethane | N Param.: 5.16 sN Param.: 0.85 | | Angew. Chem. Int. Ed. 2014, 53, 4968-4971 10.1002/anie.201402055 |
(2-methylallyl)triphenylstannane |
dichloromethane | N Param.: 5.13 sN Param.: 0.90 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |