Nucleophiles
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« Back Forward » Found 1357 molecules, displaying page 6 of 14 Results per page
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| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
(S,E)-3-benzyl-1-methyl-4-styryl-1,4-diazaspiro[4.4]nonan-2-one  |
MeCN | N Param.: 7.92 sN Param.: 1.07 |  | Angew. Chem. Int. Ed. 2012, 51, 5739-5742 10.1002/anie.201201240 |
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-(3-phenylbut-1-en-1-yl)-2,5-dihydro-1H-imidazole (in MeCN) |
MeCN | N Param.: 7.92 sN Param.: 0.73 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
borane-trimethylamine-complex |
dichloromethane | N Param.: 7.97 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
N,N-Dimethylbarbituric acid iodonium ylide (in CHCl2) |
dichloromethane | N Param.: 7.98 sN Param.: 0.71 | | J. Am. Chem. Soc. 2016, 138, 10304-10313 10.1021/jacs.6b05768 |
(E)-4-(benzylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in CH2Cl2) |
dichloromethane | N Param.: 7.99 sN Param.: 0.98 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
chloride (in hexafluoroisopropanol) |
HFIP | N Param.: 8.00 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
HRu(CO)2Cp* |
dichloromethane | N Param.: 8.00 sN Param.: 0.80 |  | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
2,5-dimethylpyrrole |
MeCN | N Param.: 8.01 sN Param.: 0.96 | | Eur. J. Org. Chem. 2008, , 2369-2374 10.1002/ejoc.200800092 |
lithium (5-methylthiophen-2-yl)(4-(dimethylamino)phenyl)pinacolborate |
MeCN | N Param.: 8.02 sN Param.: 0.89 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
fluoride (in 10 % aq MeCN) |
water-MeCN mix | N Param.: 8.05 sN Param.: 0.64 | | J. Org. Chem. 2012, 77, 3325-3335 10.1021/jo300141z |
N-(p-anisyl)-1,4-dihydronicotineamide |
dichloromethane | N Param.: 8.11 sN Param.: 0.92 | | Angew. Chem. Int. Ed. 2009, 48, 1958-1961 10.1002/anie.200804263 |
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in MeCN) |
MeCN | N Param.: 8.12 sN Param.: 0.88 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
lithium (5-methylfuran-2-yl)(4-(trifluoromethyl)phenyl)pinacolborate |
MeCN | N Param.: 8.13 sN Param.: 0.85 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in CH2Cl2) |
dichloromethane | N Param.: 8.13 sN Param.: 0.97 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
5-(tris(pentafluorophenyl)siloxy)-2,3-dihydrofuran |
dichloromethane | N Param.: 8.16 sN Param.: 0.67 | | Eur. J. Org. Chem. 2005, , 1760-1764 10.1002/ejoc.200400706 |
| HFe(CO)2Cp* |
dichloromethane | N Param.: 8.20 sN Param.: 0.69 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1-phenoxy-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 8.23 sN Param.: 0.81 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
(E)-4-(benzylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in MeCN) |
MeCN | N Param.: 8.30 sN Param.: 0.84 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
2-(4-nitrophenyl)-1,3-dimethyl-benzimidazoline (in MeCN) |
MeCN | N Param.: 8.36 sN Param.: 0.71 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
(2-methylallyl)dicarbonyl(cyclopentadienyl)iron(II) |
dichloromethane | N Param.: 8.45 sN Param.: 0.83 | | Helv. Chim. Acta 2005, 88, 1754-1768 10.1002/hlca.200590137 |
ethyl (E)-3-(N-morpholino)acrylate |
dichloromethane | N Param.: 8.52 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
borane-N,N-diethylaniline-complex |
dichloromethane | N Param.: 8.53 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1-methyl uracil anion (in water) |
water | N Param.: 8.54 sN Param.: 0.77 | | Chem. Eur. J. 2012, 18, 127-137 10.1002/chem.201102411 |
lithium 4,4,5,5-tetramethyl-2-(1-phenylethyl)-2-(4-(trifluoromethyl)phenyl)-1,3,2-dioxaborolan-2-uide (in MeCN) |
MeCN | N Param.: 8.56 sN Param.: 0.76 | | Org. Lett. 2015, 17, 2614-2617 10.1021/acs.orglett.[...] |
tris(2-methylphenyl)phosphane |
dichloromethane | N Param.: 8.56 sN Param.: 0.70 | | Chem. Eur. J. 2017, 23, 7422-7427 10.1002/chem.201701080 |
Danishefskys diene |
dichloromethane | N Param.: 8.57 sN Param.: 0.84 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
N-methyl-1-phenylmethanimine (in CH2Cl2) |
dichloromethane | N Param.: 8.60 sN Param.: 0.77 | | Z. Naturforsch. B 2013, 68b, 693-699 10.5560/ZNB.2013-3085 |
N-benzyl-1,4-dihydronicotineamide |
dichloromethane | N Param.: 8.67 sN Param.: 0.82 | | Angew. Chem. Int. Ed. 2009, 48, 1958-1961 10.1002/anie.200804263 |
1,2,5-trimethylpyrrole |
MeCN | N Param.: 8.69 sN Param.: 1.07 | | Eur. J. Org. Chem. 2008, , 2369-2374 10.1002/ejoc.200800092 |
lithium 2-allyl-2-(3,5-bis(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-uide (in MeCN) |
MeCN | N Param.: 8.71 sN Param.: 0.80 | | J. Am. Chem. Soc. 2017, 139, 15324-15327 10.1021/jacs.7b10240 |
2-(4-(trifluoromethyl)phenyl)-1,3-dimethyl-benzimidazoline (in MeCN) |
MeCN | N Param.: 8.74 sN Param.: 0.71 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
(2S,5S)-5-benzyl-3-methyl-2-(5-methylfuran-2-yl)imidazolidin-4-one |
MeCN | N Param.: 8.76 sN Param.: 0.89 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
potassium trifluoro(1-methyl-1H-indol-5-yl)borate |
MeCN | N Param.: 8.77 sN Param.: 1.09 | | J. Am. Chem. Soc. 2013, 135, 6317-6324 10.1021/ja4017655 |
(E)-4-(1,2-diphenylvinyl)morpholine (in MeCN) |
MeCN | N Param.: 8.78 sN Param.: 0.83 | | Chem. Eur. J. 2018, 24, 5901-5910 10.1002/chem.201705962 |
N-phenylcyclohexanimine (in CH2Cl2) |
dichloromethane | N Param.: 8.80 sN Param.: 1.00 | | Z. Naturforsch. B 2013, 68b, 693-699 10.5560/ZNB.2013-3085 |
borane-N,N-diisopropylaniline-complex |
dichloromethane | N Param.: 8.84 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
(p-bromophenyl)diazomethane |
dichloromethane | N Param.: 8.87 sN Param.: 0.82 | | J. Am. Chem. Soc. 2018, 140, 16758-16772 10.1021/jacs.8b09995 |
borane-triethylamine-complex |
dichloromethane | N Param.: 8.90 sN Param.: 0.75 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
lithium 2-benzyl-4,4,5,5-tetramethyl-2-phenyl-1,3,2-dioxaborolan-2-uide (in MeCN) |
MeCN | N Param.: 8.92 sN Param.: 0.70 | | Org. Lett. 2015, 17, 2614-2617 10.1021/acs.orglett.[...] |
(trimethylsilyl)diazomethane |
dichloromethane | N Param.: 8.97 sN Param.: 0.75 | | Chem. Eur. J. 2003, 9, 4068-4076 10.1002/chem.200304913 |
1-methoxy-2-methyl-1-(trimethylsiloxy)propene |
dichloromethane | N Param.: 9.00 sN Param.: 0.98 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
Hantzsch ester |
dichloromethane | N Param.: 9.00 sN Param.: 0.90 | | Angew. Chem. Int. Ed. 2009, 48, 1958-1961 10.1002/anie.200804263 |
trimethyl phosphite (in 91M9AN) |
MeOH-MeCN mix | N Param.: 9.04 sN Param.: 0.70 | | Angew. Chem. Int. Ed. 2006, 45, 3869-3874 10.1002/anie.200600542 |
tetrakis(5-methyl-furan-2-yl)borate |
MeCN | N Param.: 9.09 sN Param.: 1.12 | | Chem. Sci. 2012, 3, 878-882 10.1039/c2sc00883a |
Ph3P=CH-CHO (in MeCN) |
MeCN | N Param.: 9.09 sN Param.: 0.74 | | J. Am. Chem. Soc. 2016, 138, 11272-11281 10.1021/jacs.6b06264 |
1-methoxy-2-methyl-1-(trimethylsiloxy)propene (in MeCN) |
MeCN | N Param.: 9.11 sN Param.: 0.88 | | J. Am. Chem. Soc. 2013, 135, 6579-6587 10.1021/ja401106x |
2,6-dimethylpyridine (in MeCN) |
MeCN | N Param.: 9.11 sN Param.: 0.69 | | Synthesis 2017, 49, 3495-3504 10.1055/s-0036-1590504 |
borane-N-ethyl-N-isopropylaniline-complex |
dichloromethane | N Param.: 9.12 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
2-tritylpyrrolidine |
MeCN | N Param.: 9.16 sN Param.: 1.39 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
(E)-2-((1-(but-1-en-1-yl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN) |
MeCN | N Param.: 9.23 sN Param.: 0.74 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
2-((2,2,5,5-tetramethyl-1-(prop-1-en-1-yl)-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN) |
MeCN | N Param.: 9.25 sN Param.: 0.84 | | Chem. Commun. 2023, 59, 8091-8084 10.1039/d3cc01912h |
2,4,6-trimethylpyridine (in CH2Cl2) |
dichloromethane | N Param.: 9.34 sN Param.: 0.71 | | Synthesis 2017, 49, 3495-3504 10.1055/s-0036-1590504 |
phenyldiazomethane |
dichloromethane | N Param.: 9.35 sN Param.: 0.83 | | Chem. Eur. J. 2003, 9, 4068-4076 10.1002/chem.200304913 |
2-(3-chlorophenyl)-1,3-dimethyl-benzimidazoline (in MeCN) |
MeCN | N Param.: 9.38 sN Param.: 0.71 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
2,4,6-trimethylpyridine (in MeCN) |
MeCN | N Param.: 9.39 sN Param.: 0.60 | | Synthesis 2017, 49, 3495-3504 10.1055/s-0036-1590504 |
ethyl (E)-3-(dimethylamino)acrylate |
dichloromethane | N Param.: 9.43 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
2-methyl-imidazole (in water) |
water | N Param.: 9.45 sN Param.: 0.54 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
ammonia (in water) |
water | N Param.: 9.48 sN Param.: 0.59 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
lithium (E)-2-(3,5-bis(trifluoromethyl)phenyl)-2-(but-2-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-uide (in MeCN) |
MeCN | N Param.: 9.49 sN Param.: 0.82 | | J. Am. Chem. Soc. 2017, 139, 15324-15327 10.1021/jacs.7b10240 |
N-phenylpropan-2-imine (in CH2Cl2) |
dichloromethane | N Param.: 9.53 sN Param.: 0.85 | | Z. Naturforsch. B 2013, 68b, 693-699 10.5560/ZNB.2013-3085 |
Ph3P=CH-COPh |
dichloromethane | N Param.: 9.54 sN Param.: 0.97 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
dipp Imd boronate |
dichloromethane | N Param.: 9.55 sN Param.: 0.81 | | Org. Lett. 2012, 14, 82-85 10.1021/ol202836p |
potassium trifluoro(1-methyl-1H-indol-2-yl)borate |
MeCN | N Param.: 9.55 sN Param.: 1.16 | | J. Am. Chem. Soc. 2013, 135, 6317-6324 10.1021/ja4017655 |
imidazole (in water) |
water | N Param.: 9.63 sN Param.: 0.57 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-(3-phenylprop-1-en-1-yl)-2,5-dihydro-1H-imidazole (in MeCN) |
MeCN | N Param.: 9.64 sN Param.: 0.70 | | Chem. Eur. J. 2024, 30, e202302764 10.1002/chem.202302764 |
2-phenyl-1,3-dimethyl-benzimidazoline |
MeCN | N Param.: 9.72 sN Param.: 0.72 | | Chem. Asian J. 2009, 4, 1824-1829 10.1002/asia.200900322 |
fluoride (in 60% aq MeCN) |
water-MeCN mix | N Param.: 9.75 sN Param.: 0.63 | | J. Org. Chem. 2012, 77, 3325-3335 10.1021/jo300141z |
N-benzyl-1,4-dihydronicotineamide (in 50W50AN) |
water-MeCN mix | N Param.: 9.79 sN Param.: 0.70 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
N-benzyl-1,4-dihydronicotineamide (in MeCN) |
MeCN | N Param.: 9.80 sN Param.: 0.70 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1,1-diethoxyethene |
dichloromethane | N Param.: 9.81 sN Param.: 0.81 | | Eur. J. Org. Chem. 2004, , 2791-2796 10.1002/ejoc.200400134 |
2-methyl-4,5-dihydro-1,3-oxazole (in CH2Cl2) |
dichloromethane | N Param.: 9.81 sN Param.: 0.77 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
2,6-dimethylpyridine (in CH2Cl2) |
dichloromethane | N Param.: 9.87 sN Param.: 0.68 | | Synthesis 2017, 49, 3495-3504 10.1055/s-0036-1590504 |
(S)-2-(azidodiphenylmethyl)pyrrolidine |
MeCN | N Param.: 9.90 sN Param.: 1.22 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
1-methyl-imidazole (in water) |
water | N Param.: 9.91 sN Param.: 0.55 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
(E)-1-(1,2-diphenylvinyl)piperidine (in MeCN) |
MeCN | N Param.: 9.94 sN Param.: 0.86 | | Chem. Eur. J. 2018, 24, 5901-5910 10.1002/chem.201705962 |
tributylstannane |
dichloromethane | N Param.: 9.96 sN Param.: 0.55 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
alpha-(N-morpholino)styrene |
dichloromethane | N Param.: 9.96 sN Param.: 0.79 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
cyanoborate ion (in water) |
water | N Param.: 9.99 sN Param.: 0.54 | | Org. Biomol. Chem. 2023, 21, 85-88 10.1039/D2OB02041F |
2-(p-anisyl)-1,3-dimethyl-benzimidazoline |
MeCN | N Param.: 10.01 sN Param.: 0.72 | | Chem. Asian J. 2009, 4, 1824-1829 10.1002/asia.200900322 |
borane-pyridine-complex |
dichloromethane | N Param.: 10.01 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
2-methyl-benzimidazole (in DMSO) |
DMSO | N Param.: 10.02 sN Param.: 0.85 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-(2-methyl-4,5-dihydro-1H-imidazol-1-yl)ethanone (in CH2Cl2) |
dichloromethane | N Param.: 10.03 sN Param.: 0.75 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
morpholinoisobutylene |
dichloromethane | N Param.: 10.04 sN Param.: 0.82 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
[H-B(C6F5)3]- [NEt4]+ |
MeCN | N Param.: 10.04 sN Param.: 0.73 | | Angew. Chem. Int. Ed. 2015, 54, 14508-14512 10.1002/anie.201507298 |
theophylline anion (in water) |
water | N Param.: 10.06 sN Param.: 0.71 | | Chem. Eur. J. 2012, 18, 127-137 10.1002/chem.201102411 |
chloride (in H2O) |
water | N Param.: 10.10 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
2,2,2-trifluoroethylamine (in MeCN) |
MeCN | N Param.: 10.13 sN Param.: 0.75 | | Eur. J. Org. Chem. 2009, , 6379-6385 10.1002/ejoc.200900925 |
lithium (5-methylthiophen-2-yl)(3,5-bis(trifluoromethyl)phenyl)neopentylglycolborate |
MeCN | N Param.: 10.13 sN Param.: 0.91 | | Angew. Chem. Int. Ed. 2015, 54, 2780-2783 10.1002/anie.201410562 |
2-(p-tolyl)-1,3-dimethyl-benzimidazoline |
MeCN | N Param.: 10.14 sN Param.: 0.70 | | Chem. Asian J. 2009, 4, 1824-1829 10.1002/asia.200900322 |
OH- (in 50/50 water/MeCN) |
water-MeCN mix | N Param.: 10.19 sN Param.: 0.62 | | J. Am. Chem. Soc. 2003, 125, 286-295 10.1021/ja021010y |
N-benzyl-1,4-dihydronicotineamide (in 67W33AN) |
water-MeCN mix | N Param.: 10.19 sN Param.: 0.70 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
(E)-1-styryl-2-tritylpyrrolidine (in CH2Cl2) |
dichloromethane | N Param.: 10.19 sN Param.: 1.06 | | J. Am. Chem. Soc. 2014, 136, 14263-14269 10.1021/ja508065e |
2,2,2-trifluoroethylamine (in 91M9AN) |
MeOH-MeCN mix | N Param.: 10.20 sN Param.: 0.92 | | Angew. Chem. Int. Ed. 2006, 45, 3869-3874 10.1002/anie.200600542 |
2-methyl-4,5-dihydrothiazole (in CH2Cl2) |
dichloromethane | N Param.: 10.20 sN Param.: 0.71 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
1-butoxy-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 10.21 sN Param.: 0.82 | | Eur. J. Org. Chem. 2004, , 2791-2796 10.1002/ejoc.200400134 |
2,5-dimethyl-benzimidazole (in DMSO) |
DMSO | N Param.: 10.21 sN Param.: 0.85 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
Ph3P=CH-C(O)Me (in MeCN) |
MeCN | N Param.: 10.27 sN Param.: 0.83 | | J. Am. Chem. Soc. 2016, 138, 11272-11281 10.1021/jacs.6b06264 |
chloride (in CF3CH2OH) |
TFE | N Param.: 10.30 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
alpha-(N-morpholino)styrene (in MeCN) |
MeCN | N Param.: 10.30 sN Param.: 0.80 | | Chem. Eur. J. 2018, 24, 5901-5910 10.1002/chem.201705962 |
1-butoxy-1-(t-butyl-dimethylsiloxy)ethene |
dichloromethane | N Param.: 10.32 sN Param.: 0.79 | | Eur. J. Org. Chem. 2004, , 2791-2796 10.1002/ejoc.200400134 |