Nucleophiles
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« Back Forward » Found 1357 molecules, displaying page 8 of 14 Results per page
10|50|100|all
| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
dibutylsulfide (in CH2Cl2)  |
dichloromethane | N Param.: 11.86 sN Param.: 0.74 |  | Chem. Eur. J. 2021, 21, 11367-11376 10.1002/chem.202100977 |
Me2 Imd boronate |
dichloromethane | N Param.: 11.88 sN Param.: 0.71 | | Org. Lett. 2012, 14, 82-85 10.1021/ol202836p |
1-methyl-imidazole (in MeCN) |
MeCN | N Param.: 11.90 sN Param.: 0.73 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
tetrahydrothiopyran (in CH2Cl2) |
dichloromethane | N Param.: 11.94 sN Param.: 0.75 | | Chem. Eur. J. 2021, 21, 11367-11376 10.1002/chem.202100977 |
(4-Br-C6H4)-(CO)-CH=SMe2 |
dichloromethane | N Param.: 11.95 sN Param.: 0.76 | | Angew. Chem. Int. Ed. 2009, 48, 5034-5037 10.1002/anie.200900933 |
(E)-1-(2-(4-methoxyphenyl)-1-phenylvinyl)pyrrolidine (in MeCN) |
MeCN | N Param.: 11.99 sN Param.: 0.84 | | Chem. Eur. J. 2018, 24, 5901-5910 10.1002/chem.201705962 |
chloride (in 50% aq MeCN) |
water-MeCN mix | N Param.: 12.00 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
chloride (in 60% aq MeCN) |
water-MeCN mix | N Param.: 12.00 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
isopropylamine (in water) |
water | N Param.: 12.00 sN Param.: 0.56 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
2,2-dimethyl-5-(4-nitrobenzyl)-4,6-dioxo-1,3-dioxan-5-ide (in DMSO) |
DMSO | N Param.: 12.02 sN Param.: 1.17 | | Chem. Eur. J. 2014, 20, 11069-11077 10.1002/chem.201403161 |
1-methyl-4-(N-morpholino)tetrahydropyridine |
dichloromethane | N Param.: 12.03 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
(S)-2-(diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine |
MeCN | N Param.: 12.03 sN Param.: 0.98 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
anion of phenylnitromethane (in H2O) |
water | N Param.: 12.05 sN Param.: 0.53 | | J. Org. Chem. 2004, 69, 7565-7576 10.1021/jo048773j |
(E)-1-(N-morpholino)propene |
dichloromethane | N Param.: 12.06 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
anion of Meldrum's acid (in water) |
water | N Param.: 12.06 sN Param.: 0.66 | | J. Am. Chem. Soc. 2003, 125, 12980-12986 10.1021/ja036838e |
anion of nitromethane (in water) |
water | N Param.: 12.06 sN Param.: 0.53 | | J. Org. Chem. 2004, 69, 7565-7576 10.1021/jo048773j |
methyl glycinate (in water) |
water | N Param.: 12.08 sN Param.: 0.60 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
guanosine anion (in water) |
water | N Param.: 12.09 sN Param.: 0.52 | | Chem. Eur. J. 2012, 18, 127-137 10.1002/chem.201102411 |
tetrahydroborate ion (in water) |
water | N Param.: 12.10 sN Param.: 0.79 |  | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
thiocyanate (in MeCN) |
MeCN | N Param.: 12.13 sN Param.: 0.60 | | J. Am. Chem. Soc. 2003, 125, 14126-14132 10.1021/ja037317u |
2,2,2-trifluoroethylamine (in DMSO) |
DMSO | N Param.: 12.15 sN Param.: 0.65 | | J. Am. Chem. Soc. 2003, 125, 286-295 10.1021/ja021010y |
4-aminopyridine (in H2O) |
water | N Param.: 12.19 sN Param.: 0.66 | | Chem. Eur. J. 2007, 13, 336-345 10.1002/chem.200600941 |
bromide (in 20% aq MeCN) |
water-MeCN mix | N Param.: 12.20 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
anion of 2-nitropropane (in 91M9AN) |
MeOH-MeCN mix | N Param.: 12.20 sN Param.: 0.71 | | Eur. J. Org. Chem. 2006, , 2530-2537 10.1002/ejoc.200500769 |
Ph3P=CH-CO2Et (in DMSO) |
DMSO | N Param.: 12.21 sN Param.: 0.62 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
hydroxylamine (in 91M9AN) |
MeOH-MeCN mix | N Param.: 12.23 sN Param.: 0.66 | | Angew. Chem. Int. Ed. 2006, 45, 3869-3874 10.1002/anie.200600542 |
(Z)-1-(N-morpholino)propene |
dichloromethane | N Param.: 12.26 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
glycylglycylglycine (anionic, in water) |
water | N Param.: 12.26 sN Param.: 0.63 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
(E)-1-styrylpyrrolidine (in CH2Cl2) |
dichloromethane | N Param.: 12.26 sN Param.: 0.93 | | J. Am. Chem. Soc. 2014, 136, 14263-14269 10.1021/ja508065e |
fluoride (in 90% aq MeCN) |
water-MeCN mix | N Param.: 12.27 sN Param.: 0.59 | | J. Org. Chem. 2012, 77, 3325-3335 10.1021/jo300141z |
propargylamine (in water) |
water | N Param.: 12.29 sN Param.: 0.59 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
glycineamide (in water) |
water | N Param.: 12.29 sN Param.: 0.58 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
Ph3P=CH-CN |
dichloromethane | N Param.: 12.29 sN Param.: 0.75 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
2-phenyl-4,5-dihydro-1H-imidazole (in CH2Cl2) |
dichloromethane | N Param.: 12.31 sN Param.: 0.77 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
dimethylsulfide (in CH2Cl2) |
dichloromethane | N Param.: 12.32 sN Param.: 0.72 | | Chem. Eur. J. 2021, 21, 11367-11376 10.1002/chem.202100977 |
5-(trimethylsiloxy)-2,3-dihydrofuran (in MeCN) |
MeCN | N Param.: 12.34 sN Param.: 0.72 | | J. Am. Chem. Soc. 2013, 135, 6579-6587 10.1021/ja401106x |
tert-butylamine (in MeCN) |
MeCN | N Param.: 12.35 sN Param.: 0.72 | | Eur. J. Org. Chem. 2009, , 6379-6385 10.1002/ejoc.200900925 |
anion of 5-(p-anisyl) Meldrum's acid (in DMSO) |
DMSO | N Param.: 12.35 sN Param.: 0.90 | | Eur. J. Org. Chem. 2016, , 1841-1848 10.1002/ejoc.201600107 |
4-pyrrolidinopyridine (in H2O) |
water | N Param.: 12.39 sN Param.: 0.66 | | Chem. Eur. J. 2007, 13, 336-345 10.1002/chem.200600941 |
ditert-butyl-phenylphosphane |
dichloromethane | N Param.: 12.40 sN Param.: 0.55 | | Chem. Eur. J. 2017, 23, 7422-7427 10.1002/chem.201701080 |
trimethylhydrazine (in MeCN) |
MeCN | N Param.: 12.43 sN Param.: 0.75 | | Angew. Chem. Int. Ed. 2012, 51, 1353-1356 10.1002/anie.201107315 |
borane-DMAP-complex |
dichloromethane | N Param.: 12.44 sN Param.: 0.76 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1,3-dimethylimidazolidin-2-imine |
dichloromethane | N Param.: 12.46 sN Param.: 0.87 | | ChemCatChem 2012, 4, 993-999 10.1002/cctc.201200143 |
2-pyridone anion (in water) |
water | N Param.: 12.47 sN Param.: 0.52 | | J. Am. Chem. Soc. 2010, 132, 15380-15389 10.1021/ja106962u |
benzohydrazide (in MeCN) |
MeCN | N Param.: 12.49 sN Param.: 0.66 | | J. Org. Chem. 2012, 77, 8142-8155 10.1021/jo301497g |
acetate (in 80A20W) |
aq acetone | N Param.: 12.50 sN Param.: 0.60 | | J. Am. Chem. Soc. 2008, 130, 3012-3022 10.1021/ja0765464 |
1-(1-cyclohexenyl)-4-methylpiperazine |
dichloromethane | N Param.: 12.51 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
anion of phenylnitromethane (in 91M9AN) |
MeOH-MeCN mix | N Param.: 12.51 sN Param.: 0.67 | | Eur. J. Org. Chem. 2006, , 2530-2537 10.1002/ejoc.200500769 |
(5-methyl-furan-2-yl)(1,1,1-tris(methoxy)ethane)borate |
MeCN | N Param.: 12.55 sN Param.: 0.92 | | Chem. Sci. 2012, 3, 878-882 10.1039/c2sc00883a |
5-(trimethylsiloxy)-2,3-dihydrofuran |
dichloromethane | N Param.: 12.56 sN Param.: 0.70 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
tris(4-chlorophenyl)phosphane |
dichloromethane | N Param.: 12.58 sN Param.: 0.65 | | Chem. Eur. J. 2005, 11, 917-927 10.1002/chem.200400696 |
dimethylselenide (in CH2Cl2) |
dichloromethane | N Param.: 12.60 sN Param.: 0.72 | | Chem. Eur. J. 2021, 21, 11367-11376 10.1002/chem.202100977 |
ethanolamine (in water) |
water | N Param.: 12.61 sN Param.: 0.58 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
aniline (in MeCN) |
MeCN | N Param.: 12.64 sN Param.: 0.68 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
2,2,2-trifluoroethanolate (in water) |
water | N Param.: 12.66 sN Param.: 0.59 | | J. Am. Chem. Soc. 2003, 125, 286-295 10.1021/ja021010y |
threonine (anionic, in water) |
water | N Param.: 12.69 sN Param.: 0.60 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
dimethylsulfide (in MeCN) |
MeCN | N Param.: 12.70 sN Param.: 0.72 | | Chem. Eur. J. 2021, 21, 11367-11376 10.1002/chem.202100977 |
acetate (in 90A10W) |
aq acetone | N Param.: 12.71 sN Param.: 0.68 | | J. Am. Chem. Soc. 2008, 130, 3012-3022 10.1021/ja0765464 |
Desoxy Breslow intermediate 2c' |
THF | N Param.: 12.75 sN Param.: 0.71 | | Angew. Chem. Int. Ed. 2012, 51, 6231-6235 10.1002/anie.201202327 |
bromite (in water) |
water | N Param.: 12.75 sN Param.: 0.59 | | Org. Lett. 2018, 20, 2816-2820 10.1021/acs.orglett.[...] |
Ph3P=CH-CO2Et |
dichloromethane | N Param.: 12.79 sN Param.: 0.77 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
bromide (in 40% aq MeCN) |
water-MeCN mix | N Param.: 12.80 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
hydroxylamine (in MeCN) |
MeCN | N Param.: 12.80 sN Param.: 0.63 | | J. Org. Chem. 2012, 77, 8142-8155 10.1021/jo301497g |
ethylamine (in water) |
water | N Param.: 12.87 sN Param.: 0.58 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
1-(phenylmethylamino)cyclopentene |
dichloromethane | N Param.: 12.90 sN Param.: 0.79 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
chloride (in MeOH) |
MeOH | N Param.: 12.90 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
pyridine (in CH2Cl2) |
dichloromethane | N Param.: 12.90 sN Param.: 0.67 | | Chem. Eur. J. 2007, 13, 336-345 10.1002/chem.200600941 |
glycylglycine (anionic, in water) |
water | N Param.: 12.91 sN Param.: 0.59 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
4-chloroaniline (in MeCN) |
MeCN | N Param.: 12.92 sN Param.: 0.60 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
2-methyl-4,5-dihydro-1H-imidazole (in CH2Cl2) |
dichloromethane | N Param.: 12.92 sN Param.: 0.77 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
(R)-2-(tert-butyl)-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine |
dichloromethane | N Param.: 12.95 sN Param.: 0.58 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
arginine (betaine, in water) |
water | N Param.: 12.96 sN Param.: 0.57 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
3-bromo-4-(dimethylamino)pyridine (in MeCN) |
MeCN | N Param.: 12.96 sN Param.: 0.67 | | J. Phys. Chem. A 2012, 116, 8494-8499 10.1021/jp3049247 |
2,3,5,6-tetrahydroimidazo[2,1-b]thiazole |
dichloromethane | N Param.: 12.98 sN Param.: 0.81 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
aniline (in water) |
water | N Param.: 12.99 sN Param.: 0.73 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
chloride (in 80% aq EtOH) |
water-EtOH mix | N Param.: 13.00 sN Param.: 0.60 | | J. Am. Chem. Soc. 2005, 127, 2641-2649 10.1021/ja045562n |
p-toluidine (in water) |
water | N Param.: 13.00 sN Param.: 0.79 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
diethanolamine (in water) |
water | N Param.: 13.00 sN Param.: 0.61 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
3,5,6,7-tetrahydro-2H-imidazo[2,1-b][1,3]thiazine |
dichloromethane | N Param.: 13.00 sN Param.: 0.83 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
alanine (anionic, in water) |
water | N Param.: 13.01 sN Param.: 0.58 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
O-HyperBTM (in CH2Cl2) |
dichloromethane | N Param.: 13.01 sN Param.: 0.73 | | Angew. Chem. Int. Ed. 2025, 64, e202514865 10.1002/anie.202514865 |
asparagine (anionic, in water) |
water | N Param.: 13.03 sN Param.: 0.53 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
BTM (in CH2Cl2) |
dichloromethane | N Param.: 13.06 sN Param.: 0.73 | | Angew. Chem. Int. Ed. 2025, 64, e202514865 10.1002/anie.202514865 |
anion of p-tolylnitromethane (in water) |
water | N Param.: 13.09 sN Param.: 0.50 | | J. Org. Chem. 2004, 69, 7565-7576 10.1021/jo048773j |
Ph3P=C(CH3)-CO2Et |
dichloromethane | N Param.: 13.09 sN Param.: 0.73 | | J. Am. Chem. Soc. 2009, 131, 704-714 10.1021/ja8056216 |
tetrahydrothiophene (in CH2Cl2) |
dichloromethane | N Param.: 13.10 sN Param.: 0.72 | | Chem. Eur. J. 2021, 21, 11367-11376 10.1002/chem.202100977 |
1-benzyl-2-phenyl-4,5-dihydro-1H-imidazole (in CH2Cl2) |
dichloromethane | N Param.: 13.11 sN Param.: 0.83 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
2-methyl-4,5-dihydro-3H-pyrrole (in CH2Cl2) |
dichloromethane | N Param.: 13.12 sN Param.: 0.69 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
7-MeO-BTM (in CH2Cl2) |
dichloromethane | N Param.: 13.15 sN Param.: 0.75 | | Angew. Chem. Int. Ed. 2025, 64, e202514865 10.1002/anie.202514865 |
serine (anionic, in water) |
water | N Param.: 13.16 sN Param.: 0.55 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
methionine (anionic, in water) |
water | N Param.: 13.16 sN Param.: 0.58 | | Org. Biomol. Chem. 2007, 5, 3814-3820 10.1039/b713778h |
4-(dimethylamino)pyridine (in H2O) |
water | N Param.: 13.19 sN Param.: 0.56 | | Chem. Eur. J. 2007, 13, 336-345 10.1002/chem.200600941 |
p-toluidine (in MeCN) |
MeCN | N Param.: 13.19 sN Param.: 0.69 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
4-(dimethylamino)pyridine (in 91M9AN) |
MeOH-MeCN mix | N Param.: 13.20 sN Param.: 0.67 | | Chem. Eur. J. 2007, 13, 336-345 10.1002/chem.200600941 |
fluoride (in 80% aq EtOH) |
water-EtOH mix | N Param.: 13.20 sN Param.: 0.53 | | J. Org. Chem. 2012, 77, 3325-3335 10.1021/jo300141z |
allylamine (in water) |
water | N Param.: 13.21 sN Param.: 0.54 | | J. Org. Chem. 2007, 72, 3679-3688 10.1021/jo062586z |
anion of (4-cyanophenyl)nitromethane (in water) |
water | N Param.: 13.23 sN Param.: 0.52 | | J. Org. Chem. 2004, 69, 7565-7576 10.1021/jo048773j |
ethanolamine (in 91M9AN) |
MeOH-MeCN mix | N Param.: 13.23 sN Param.: 0.65 | | Angew. Chem. Int. Ed. 2006, 45, 3869-3874 10.1002/anie.200600542 |
di(methoxyethyl)amine (in MeCN) |
MeCN | N Param.: 13.24 sN Param.: 0.93 | | Eur. J. Org. Chem. 2009, , 6379-6385 10.1002/ejoc.200900925 |
4-acetamido-pyridine (in MeCN) |
MeCN | N Param.: 13.24 sN Param.: 0.67 | | J. Phys. Chem. A 2012, 116, 8494-8499 10.1021/jp3049247 |