Other Michael acceptors
| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
benzylidenemalononitrile   |
E Param.: -9.42 |
 |
J. Org. Chem. 2003, 68, 6880-6886 10.1021/jo0344182 |
|
p-(methoxy)benzylidenemalononitrile  |
E Param.: -10.80 |
|
J. Org. Chem. 2003, 68, 6880-6886 10.1021/jo0344182 |
|
p-(dimethylamino)benzylidenemalononitrile  |
E Param.: -13.30 |
|
J. Org. Chem. 2003, 68, 6880-6886 10.1021/jo0344182 |
|
2-(p-(dimethylamino)benzylidene)-indan-1,3-dione  |
E Param.: -13.56 |
|
Org. Biomol. Chem. 2007, 5, 3020-3026 10.1039/b708025e |
|
2-(p-methoxybenzylidene)-indan-1,3-dione  |
E Param.: -11.32 |
|
Org. Biomol. Chem. 2007, 5, 3020-3026 10.1039/b708025e |
|
2-benzylidene-indan-1,3-dione  |
E Param.: -10.11 |
|
Org. Biomol. Chem. 2007, 5, 3020-3026 10.1039/b708025e |
|
jul-indan-1,3-dione  |
E Param.: -14.68 |
|
Org. Biomol. Chem. 2007, 5, 3020-3026 10.1039/b708025e |
|
aniBBS  |
E Param.: -10.37 |
|
J. Org. Chem. 2007, 72, 9170-9180 10.1021/jo071273g |
|
dmaBBS  |
E Param.: -12.76 |
|
J. Org. Chem. 2007, 72, 9170-9180 10.1021/jo071273g |
|
julBBS  |
E Param.: -13.84 |
|
J. Org. Chem. 2007, 72, 9170-9180 10.1021/jo071273g |
|
dma(S)BBS  |
E Param.: -10.73 |
|
J. Org. Chem. 2007, 72, 9170-9180 10.1021/jo071273g |
|
jul(S)BBS  |
E Param.: -11.89 |
|
J. Org. Chem. 2007, 72, 9170-9180 10.1021/jo071273g |
|
benzylidene-Meldrum's acid  |
E Param.: -9.15 |
|
J. Org. Chem. 2008, 73, 2738-2745 10.1021/jo702590s |
|
p-(methoxy)benzylidene Meldrum's acid  |
E Param.: -10.28 |
|
J. Org. Chem. 2008, 73, 2738-2745 10.1021/jo702590s |
|
p-(dimethylamino)benzylidene Meldrum's acid  |
E Param.: -12.76 |
|
J. Org. Chem. 2008, 73, 2738-2745 10.1021/jo702590s |
|
jul Meldrum's acid  |
E Param.: -13.97 |
|
J. Org. Chem. 2008, 73, 2738-2745 10.1021/jo702590s |
|
(E)-3-(4-nitro-phenyl)-1-phenyl-prop-2-en-1-one (in DMSO)  |
DMSO | E Param.: -17.33 |
|
J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-3-(4-cyano-phenyl)-1-phenyl-prop-2-en-1-one (in DMSO)  |
DMSO | E Param.: -17.64 |
|
J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-1,3-diphenylprop-2-en-1-one (in DMSO)  |
DMSO | E Param.: -19.39 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
(E)-4-(4-nitrophenyl)but-3-en-2-one (in DSMO)  |
DMSO | E Param.: -19.36 |
|
J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-4-methyl-1-(4-nitrophenyl)pent-1-en-3-one (in DMSO)  |
DMSO | E Param.: -19.17 |
|
J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
(E)-4,4-dimethyl-1-(4-nitrophenyl)pent-1-en-3-one  |
DMSO | E Param.: -19.15 |
|
J. Am. Chem. Soc. 2011, 133, 8240-8251 10.1021/ja200820m |
maleic anhydride  |
DMSO | E Param.: -11.31 |
|
Eur. J. Org. Chem. 2014, , 2956-2963 10.1002/ejoc.201301779 |
N-methyl maleimide  |
DMSO | E Param.: -14.07 |
|
Eur. J. Org. Chem. 2014, , 2956-2963 10.1002/ejoc.201301779 |
fumaronitrile  |
DMSO | E Param.: -15.71 |
|
Eur. J. Org. Chem. 2014, , 2956-2963 10.1002/ejoc.201301779 |
diethyl fumarate  |
DMSO | E Param.: -17.79 |
|
Eur. J. Org. Chem. 2014, , 2956-2963 10.1002/ejoc.201301779 |
diethyl maleate  |
DMSO | E Param.: -19.49 |
|
Eur. J. Org. Chem. 2014, , 2956-2963 10.1002/ejoc.201301779 |
ethenesulfonyl fluoride (ESF)  |
DMSO | E Param.: -12.09 |
|
Angew. Chem. Int. Ed. 2016, 55, 12664-12667 10.1002/anie.201601875 |
2-phenylethene-1-sulfonyl fluoride  |
DMSO | E Param.: -16.63 |
|
Angew. Chem. Int. Ed. 2016, 55, 12664-12667 10.1002/anie.201601875 |
(E)-4-phenylbut-3-en-2-one (in DMSO)  |
DMSO | E Param.: -23.01 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
cinnamonitrile (in DMSO)  |
DMSO | E Param.: -24.60 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
methyl prop-2-enoate (in DMSO)  |
DMSO | E Param.: -18.84 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
ethyl prop-2-enoate (in DMSO)  |
DMSO | E Param.: -19.07 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
tert-butyl prop-2-enoate (in DMSO)  |
DMSO | E Param.: -20.22 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
N,N-dimethylprop-2-enamide (in DMSO)  |
DMSO | E Param.: -23.54 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
ethenylsulfonylbenzene (in DMSO)  |
DMSO | E Param.: -18.36 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
acrylonitrile (in DMSO)  |
DMSO | E Param.: -19.05 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
but-3-en-2-one (in DMSO)  |
DMSO | E Param.: -16.76 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
1-phenylprop-2-en-1-one (in DMSO)  |
DMSO | E Param.: -15.25 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
ethyl 2-methylprop-2-enoate (in DMSO)  |
DMSO | E Param.: -22.77 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
ethyl (E)-but-2-enoate (in DMSO)  |
DMSO | E Param.: -23.59 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
ethyl cinnamate (in DMSO)  |
DMSO | E Param.: -24.52 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
(E)-1-methyl-4-(styrylsulfonyl)benzene (in DMSO)  |
DMSO | E Param.: -24.69 |
|
J. Am. Chem. Soc. 2017, 139, 13318-13329 10.1021/jacs.7b05106 |
3-methylcyclopentenone  |
DMSO | E Param.: -28.90 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |
2-methylcyclopentenone  |
DMSO | E Param.: -22.10 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |
cyclopentenone  |
DMSO | E Param.: -20.60 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |
furan-2(5H)-one  |
DMSO | E Param.: -20.70 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |
2-methylcyclohexenone  |
DMSO | E Param.: -27.50 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |
cyclohexenone  |
DMSO | E Param.: -22.10 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |
dihydro-2H-pyran-2-one  |
DMSO | E Param.: -21.80 |
|
Chem. Sci. 2021, 12, 4850-4865 10.1039/D0SC06628A |