Mayr's Database of Reactivity Parameters

Nucleophiles

1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 Found 1310 molecules, displaying page 4 of 14 Results per page 10|50|100|all
Name Solvent Reactivity
Parameters 		Classification Reference
(title or year)
ethanolate (in 91E9AN)
C2H5O-*
 EtOH-MeCN mix

N  Param.: 16.08

sN Param.: 0.62		***Can. J. Chem. 2005, 83, 1554-1560
10.1139%2Fv05-170
n-propanolate (in 91nPr9AN)
C3H8O-*
 nPrOH-MeCN mix

N  Param.: 16.73

sN Param.: 0.63		***Can. J. Chem. 2005, 83, 1554-1560
10.1139%2Fv05-170
isopropanolate (in 91iPr9AN)
C3H8O-*
 iPrOH-MeCN mix

N  Param.: 17.71

sN Param.: 0.58		***Can. J. Chem. 2005, 83, 1554-1560
10.1139%2Fv05-170
Indole
C8H7N*
 dichloromethane

N  Param.: 5.55

sN Param.: 1.09		***J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
N-methylindole
C9H9N*
 dichloromethane

N  Param.: 5.75

sN Param.: 1.23		***J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
1,2-dimethylindole
C10H11N*
 dichloromethane

N  Param.: 6.54

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
anion of nitromethane (in 91M9AN)
CH2NO2-*
 MeOH-MeCN mix

N  Param.: 14.02

sN Param.: 0.61		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of nitroethane (in 91M9AN)
C2H4NO2-*
 MeOH-MeCN mix

N  Param.: 13.41

sN Param.: 0.67		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of 2-nitropropane (in 91M9AN)
C3H6NO2-*
 MeOH-MeCN mix

N  Param.: 12.20

sN Param.: 0.71		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of phenylnitromethane (in 91M9AN)
C7H6NO2-*
 MeOH-MeCN mix

N  Param.: 12.51

sN Param.: 0.67		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of p-tolylnitromethane (in 91M9AN)
C8H8NO2-*
 MeOH-MeCN mix

N  Param.: 13.58

sN Param.: 0.64		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of (4-nitrophenyl)nitromethane (in 91M9AN)
C7H5N2O4-*
 MeOH-MeCN mix

N  Param.: 14.05

sN Param.: 0.72		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of (3-nitrophenyl)nitromethane (in 91M9AN)
C7H5N2O4-*
 MeOH-MeCN mix

N  Param.: 14.75

sN Param.: 0.71		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of (4-cyanophenyl)nitromethane (in 91M9AN)
C8H5N2O2-*
 MeOH-MeCN mix

N  Param.: 13.92

sN Param.: 0.74		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of ethyl cyanoacetate (in 91M9AN)
C5H6NO2-*
 MeOH-MeCN mix

N  Param.: 18.59

sN Param.: 0.65		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of malononitrile (in 91M9AN)
C3HN2-*
 MeOH-MeCN mix

N  Param.: 18.21

sN Param.: 0.69		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
anion of dimethyl malonate (in 91M9AN)
C5H7O4-*
 MeOH-MeCN mix

N  Param.: 18.24

sN Param.: 0.64		***Eur. J. Org. Chem. 2006, , 2530-2537
10.1002/ejoc.200500769
azide ion (in 91M9AN)
N3-*
 MeOH-MeCN mix

N  Param.: 14.54

sN Param.: 0.82		***J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 91E9AN)
N3-*
 EtOH-MeCN mix

N  Param.: 16.30

sN Param.: 0.73		***J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 91nPr9AN)
N3-*
 nPrOH-MeCN mix

N  Param.: 16.70

sN Param.: 0.73		***J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 91iPr9AN)
N3-*
 iPrOH-MeCN mix

N  Param.: 17.07

sN Param.: 0.71		***J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in DMSO)
N3-*
 DMSO

N  Param.: 20.50

sN Param.: 0.59		***J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
azide ion (in 45M55AN)
N3-*
 MeOH-MeCN mix

N  Param.: 15.01

sN Param.: 0.80		***J. Phys. Org. Chem. 2006, 19, 706-713
10.1002/poc.1063
pyrrolidine (in 91M9AN)
C4H9N*
 MeOH-MeCN mix

N  Param.: 15.97

sN Param.: 0.63		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
piperidine (in 91M9AN)
C5H11N*
 MeOH-MeCN mix

N  Param.: 15.63

sN Param.: 0.64		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
morpholine (in 91M9AN)
C4H9NO*
 MeOH-MeCN mix

N  Param.: 15.40

sN Param.: 0.64		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
diethanolamine (in 91M9AN)
C4H11NO2*
 MeOH-MeCN mix

N  Param.: 13.71

sN Param.: 0.67		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
hydrazine (in 91M9AN)
H4N2*
 MeOH-MeCN mix

N  Param.: 13.47

sN Param.: 0.70		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
trimethyl phosphite (in 91M9AN)
C3H9O3P*
 MeOH-MeCN mix

N  Param.: 9.04

sN Param.: 0.70		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
2,2,2-trifluoroethylamine (in 91M9AN)
C2H4F3N*
 MeOH-MeCN mix

N  Param.: 10.20

sN Param.: 0.92		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
imidazole (in 91M9AN)
C3H4N2*
 MeOH-MeCN mix

N  Param.: 10.41

sN Param.: 0.70		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
hydroxylamine (in 91M9AN)
H3NO*
 MeOH-MeCN mix

N  Param.: 12.23

sN Param.: 0.66		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
ethanolamine (in 91M9AN)
C2H7NO*
 MeOH-MeCN mix

N  Param.: 13.23

sN Param.: 0.65		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
benzylamine (in 91M9AN)
C7H9N*
 MeOH-MeCN mix

N  Param.: 13.46

sN Param.: 0.62		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
n-propylamine (in 91M9AN)
C3H9N*
 MeOH-MeCN mix

N  Param.: 13.41

sN Param.: 0.66		***Angew. Chem. Int. Ed. 2006, 45, 3869-3874
10.1002/anie.200600542
5-methoxy-indole
C9H9NO*
 dichloromethane

N  Param.: 6.22

sN Param.: 1.12		***J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-amino-indole
C8H8N2*
 MeCN

N  Param.: 7.22

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-hydroxy-indole
C8H7NO*
 MeCN

N  Param.: 6.44

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-methyl-indole
C9H9N*
 MeCN

N  Param.: 6.00

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-chloro-indole
C8H6ClN*
 MeCN

N  Param.: 4.42

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-bromo-indole
C8H6BrN*
 MeCN

N  Param.: 4.38

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-cyano-indole
C9H6N2*
 MeCN

N  Param.: 2.83

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
1H-indole-5-carboxylic acid
C9H7NO2*
 MeCN

N  Param.: 3.97

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-methoxy-2-methylindole
C10H11NO*
 MeCN

N  Param.: 7.26

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
2,5-dimethylindole
C10H11N*
 MeCN

N  Param.: 7.22

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
2-methylindole
C9H9N*
 MeCN

N  Param.: 6.91

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
5-chloro-2-methylindole
C9H8ClN*
 MeCN

N  Param.: 6.08

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
4-methoxy-indole
C9H9NO*
 MeCN

N  Param.: 5.41

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
7-azaindole
C7H6N2*
 MeCN

N  Param.: 3.87

sN Param.: 1.10		*J. Org. Chem. 2006, 71, 9088-9095
10.1021/jo0614339
4-chloropyridine (in CH2Cl2)
C5H4ClN*
 dichloromethane

N  Param.: 11.70

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-chloropyridine (in H2O)
C5H4ClN*
 water

N  Param.: 10.50

sN Param.: 0.73		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
pyridine (in CH2Cl2)
C5H5N*
 dichloromethane

N  Param.: 12.90

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
pyridine (in H2O)
C5H5N*
 water

N  Param.: 11.05

sN Param.: 0.73		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-methylpyridine (in CH2Cl2)
C6H7N*
 dichloromethane

N  Param.: 13.70

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-methylpyridine (in H2O)
C6H7N*
 water

N  Param.: 11.10

sN Param.: 0.75		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-methoxypyridine (in CH2Cl2)
C6H7NO*
 dichloromethane

N  Param.: 13.70

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-methoxypyridine (in H2O)
C6H7NO*
 water

N  Param.: 11.44

sN Param.: 0.68		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-aminopyridine (in CH2Cl2)
C5H6N2*
 dichloromethane

N  Param.: 15.20

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-aminopyridine (in H2O)
C5H6N2*
 water

N  Param.: 12.19

sN Param.: 0.66		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-(dimethylamino)pyridine (in CH2Cl2)
C7H10N2*
 dichloromethane

N  Param.: 15.80

sN Param.: 0.66		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-(dimethylamino)pyridine (in H2O)
C7H10N2*
 water

N  Param.: 13.19

sN Param.: 0.56		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-(dimethylamino)pyridine (in 91M9AN)
C7H10N2*
 MeOH-MeCN mix

N  Param.: 13.20

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-(dimethylamino)pyridine (in DMSO)
C7H10N2*
 DMSO

N  Param.: 14.80

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-(dimethylamino)pyridine (in DMF)
C7H10N2*
 DMF

N  Param.: 14.90

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-pyrrolidinopyridine (in CH2Cl2)
C9H12N2*
 dichloromethane

N  Param.: 15.90

sN Param.: 0.67		*Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
4-pyrrolidinopyridine (in H2O)
C9H12N2*
 water

N  Param.: 12.39

sN Param.: 0.66		***Chem. Eur. J. 2007, 13, 336-345
10.1002/chem.200600941
tert-butyl isocyanide
C5H9N*
 dichloromethane

N  Param.: 5.47

sN Param.: 0.77		***Angew. Chem. Int. Ed. 2007, 46, 3563-3566
10.1002/anie.200605205
benzyl isocyanide
C8H7N*
 dichloromethane

N  Param.: 4.90

sN Param.: 0.74		***Angew. Chem. Int. Ed. 2007, 46, 3563-3566
10.1002/anie.200605205
2,6-dimethylphenyl isocyanide
C9H9N*
 dichloromethane

N  Param.: 4.59

sN Param.: 0.87		***Angew. Chem. Int. Ed. 2007, 46, 3563-3566
10.1002/anie.200605205
p-tosylmethyl isocyanide (TosMIC)
C9H9NO2S*
 dichloromethane

N  Param.: 3.50

sN Param.: 0.76		***Angew. Chem. Int. Ed. 2007, 46, 3563-3566
10.1002/anie.200605205
4-cyanophenyl isocyanide
C8H4N2*
 dichloromethane

N  Param.: 3.57

sN Param.: 0.72		**Angew. Chem. Int. Ed. 2007, 46, 3563-3566
10.1002/anie.200605205
ammonia (in water)
H3N*
 water

N  Param.: 9.48

sN Param.: 0.59		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
methylamine (in water)
CH5N*
 water

N  Param.: 13.85

sN Param.: 0.53		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
ethylamine (in water)
C2H7N*
 water

N  Param.: 12.87

sN Param.: 0.58		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
isopropylamine (in water)
C3H9N*
 water

N  Param.: 12.00

sN Param.: 0.56		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
tert-butylamine (in water)
C4H11N*
 water

N  Param.: 10.48

sN Param.: 0.65		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
dimethylamine (in water)
C2H7N*
 water

N  Param.: 17.12

sN Param.: 0.50		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
diethylamine (in water)
C4H11N*
 water

N  Param.: 14.68

sN Param.: 0.53		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
pyrrolidine (in water)
C4H9N*
 water

N  Param.: 17.21

sN Param.: 0.49		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
piperidine (in water)
C5H11N*
 water

N  Param.: 18.13

sN Param.: 0.44		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
morpholine (in water)
C4H9NO*
 water

N  Param.: 15.62

sN Param.: 0.54		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
piperazine (in water)
C4H10N2*
 water

N  Param.: 17.22

sN Param.: 0.50		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
perhydroazepine (in water)
C6H13N*
 water

N  Param.: 18.29

sN Param.: 0.46		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
glycinenitrile (in water)
*
 water

N  Param.: 10.80

sN Param.: 0.61		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
ethanolamine (in water)
C2H7NO*
 water

N  Param.: 12.61

sN Param.: 0.58		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
ethylenediamine (in water)
C2H8N2*
 water

N  Param.: 13.28

sN Param.: 0.58		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
propargylamine (in water)
C3H5N*
 water

N  Param.: 12.29

sN Param.: 0.59		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
allylamine (in water)
C3H7N*
 water

N  Param.: 13.21

sN Param.: 0.54		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
benzylamine (in water)
C7H9N*
 water

N  Param.: 13.44

sN Param.: 0.55		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
4-chloroaniline (in MeCN)
C6H6ClN*
 MeCN

N  Param.: 12.92

sN Param.: 0.60		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
aniline (in water)
C6H7N*
 water

N  Param.: 12.99

sN Param.: 0.73		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
aniline (in MeCN)
C6H7N*
 MeCN

N  Param.: 12.64

sN Param.: 0.68		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
p-toluidine (in water)
C7H9N*
 water

N  Param.: 13.00

sN Param.: 0.79		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
p-toluidine (in MeCN)
C7H9N*
 MeCN

N  Param.: 13.19

sN Param.: 0.69		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
4-methoxyaniline (in MeCN)
C7H9NO*
 MeCN

N  Param.: 13.42

sN Param.: 0.73		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
diethanolamine (in water)
C4H11NO2*
 water

N  Param.: 13.00

sN Param.: 0.61		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
N-methyl-glycinenitrile (in water)
C3H6N2*
 water

N  Param.: 13.50

sN Param.: 0.59		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
methyl glycinate (in water)
C3H7NO2*
 water

N  Param.: 12.08

sN Param.: 0.60		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
glycineamide (in water)
C2H6N2O*
 water

N  Param.: 12.29

sN Param.: 0.58		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
1,3-diaminopropane (in water)
C3H10N2*
 water

N  Param.: 14.02

sN Param.: 0.54		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z