Mayr's Database of Reactivity Parameters

Nucleophiles

1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 « Back Found 1292 molecules, displaying page 1 of 26 Results per page 10|50|100|all
Name Solvent Reactivity
Parameters 		Classification Reference
(title or year)
1-mesityl-3-methyl-5-methylene-2,4,6-triphenyl-2,5-dihydropyridin-1-ium-2-ide (in THF)
C34H31N*
 THF

N  Param.: 26.16

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2024, , e202318283
10.1002/anie.202318283
(S)-3,3-difluoro-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine (in CH2Cl2)
C16H12F2N2S*
 dichloromethane

N  Param.: 10.83

sN Param.: 0.80		***ARKIVOC 2024, (4), 202312093
10.24820/ark.5550190[...]
cyanoborate ion (in water)
*
 water

N  Param.: 9.99

sN Param.: 0.54		***Org. Biomol. Chem. 2023, 21, 85-88
10.1039/D2OB02041F
3-diazoindolin-2-one
C8H5N3O*
 dichloromethane

N  Param.: 3.16

sN Param.: 1.03		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
NADPH (in water)
*
 water

N  Param.: 10.68

sN Param.: 0.54		***Org. Biomol. Chem. 2023, 21, 85-88
10.1039/D2OB02041F
2-diazoindan-1-one
C9H6N2O*
 dichloromethane

N  Param.: 5.61

sN Param.: 0.65		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazocyclohexanone
C6H8N2O*
 dichloromethane

N  Param.: 3.44

sN Param.: 0.83		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazo-1-tetralone
C10H8N2O*
 dichloromethane

N  Param.: 3.51

sN Param.: 0.86		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazoindandione
C9H4N2O2*
 dichloromethane

N  Param.: 0.16

sN Param.: 0.86		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazo-1-benzosuberone
C11H10N2O*
 dichloromethane

N  Param.: 2.72

sN Param.: 0.96		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazobenzothiophen-3(2H)-one
C8H4N2OS*
 dichloromethane

N  Param.: 0.40

sN Param.: 0.93		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
NADH (in water)
*
 water

N  Param.: 10.37

sN Param.: 0.54		***Org. Biomol. Chem. 2023, 21, 85-88
10.1039/D2OB02041F
2-((2,2,5,5-tetramethyl-1-(prop-1-en-1-yl)-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C12H19N3S*
 MeCN

N  Param.: 9.25

sN Param.: 0.84		***Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-((2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C17H21N3S*
 MeCN

N  Param.: 7.74

sN Param.: 0.87		***Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-((2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in CH2Cl2)
C17H21N3S*
 dichloromethane

N  Param.: 7.06

sN Param.: 1.11		***Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
1,3-Bis(2,6-diisopropylphenyl)-5-methylene-4-(2,4,6-triisopropylphenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-4-ide (in THF)
C35H39F6N3*
 THF

N  Param.: 21.36

sN Param.: 0.42		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-4-methylene-5-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C34H40F3N3*
 THF

N  Param.: 22.30

sN Param.: 0.49		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-5-(4-methoxyphenyl)-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C34H43N3O*
 THF

N  Param.: 23.55

sN Param.: 0.56		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-5-methylene-4-(2,4,6-triisopropylphenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-4-ide (in THF)
C42H59N3*
 THF

N  Param.: 20.78

sN Param.: 0.61		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Diisopropyl-4-methylene-5-phenyl-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C15H21N3*
 THF

N  Param.: 30.25

sN Param.: 0.54		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
5-(tert-Butyl)-1,3-diisopropyl-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C13H25N3*
 THF

N  Param.: 31.92

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-4-methylene-5-phenyl-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C33H41N3*
 THF

N  Param.: 22.80

sN Param.: 0.60		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-5-methyl-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C28H39N3*
 THF

N  Param.: 24.86

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
(E)-2-((1-(but-1-en-1-yl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C13H21N3S*
 MeCN

N  Param.: 9.23

sN Param.: 0.74		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in MeCN)
C17H24N2S*
 MeCN

N  Param.: 8.12

sN Param.: 0.88		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-13-(ethylthio)-6-styryl-6,12-diazadispiro[4.1.47.25]tridec-12-ene (in MeCN)
C21H28N2S*
 MeCN

N  Param.: 7.79

sN Param.: 0.87		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-(3-phenylprop-1-en-1-yl)-2,5-dihydro-1H-imidazole (in MeCN)
C18H26N2S*
 MeCN

N  Param.: 9.64

sN Param.: 0.70		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-(3-phenylbut-1-en-1-yl)-2,5-dihydro-1H-imidazole (in MeCN)
C19H28N2S*
 MeCN

N  Param.: 7.92

sN Param.: 0.73		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(benzylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in MeCN)
C22H26N2S*
 MeCN

N  Param.: 8.30

sN Param.: 0.84		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
diazocyclopentadiene (in CH2Cl2)
C5H4N2*
 dichloromethane

N  Param.: 4.84

sN Param.: 1.06		***Synthesis 2023, 55, 354-358
10.1055/s-0041-1737327
(E)-2,2,3,5,5-pentamethyl-1-styrylimidazolidin-4-one (in MeCN)
C16H22N2O*
 MeCN

N  Param.: 7.10

sN Param.: 0.82		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-2,2,3,5,5-pentamethyl-1-styrylimidazolidine-4-thione (in MeCN)
C16H22N2S*
 MeCN

N  Param.: 6.49

sN Param.: 0.83		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in CH2Cl2)
C17H24N2S *
 dichloromethane

N  Param.: 8.13

sN Param.: 0.97		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(benzylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in CH2Cl2)
C22H26N2S *
 dichloromethane

N  Param.: 7.99

sN Param.: 0.98		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
lithium 4,4,5,5-tetramethyl-2-phenyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolan-2-uide (in MeCN)
C15H22BLiO2*
 MeCN

N  Param.: 11.00

sN Param.: 0.57		***J. Am. Chem. Soc. 2022, 144, 16118-16130
10.1021/jacs.2c06493
dimethylsulfide (in CH2Cl2)
C2H6S*
 dichloromethane

N  Param.: 12.32

sN Param.: 0.72		**Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
dimethylsulfide (in MeCN)
C2H6S*
 MeCN

N  Param.: 12.70

sN Param.: 0.72		-Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
dimethylselenide (in CH2Cl2)
C2H6Se*
 dichloromethane

N  Param.: 12.60

sN Param.: 0.72		-Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
dibutylsulfide (in CH2Cl2)
C8H18S*
 dichloromethane

N  Param.: 11.86

sN Param.: 0.74		**Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
tetrahydrothiophene (in CH2Cl2)
C4H8S*
 dichloromethane

N  Param.: 13.10

sN Param.: 0.72		-Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
tetrahydrothiophene (in MeCN)
C4H8S*
 MeCN

N  Param.: 13.30

sN Param.: 0.72		-Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
tetrahydrothiopyran (in CH2Cl2)
C5H10S*
 dichloromethane

N  Param.: 11.94

sN Param.: 0.75		**Chem. Eur. J. 2021, 21, 11367-11376
10.1002/chem.202100977
4-nitrothiophenolate (in DMSO)
C6H4NO2S-*
 DMSO

N  Param.: 18.92

sN Param.: 0.87		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
3,5-bis(trifluoromethyl)thiophenolate (in DMSO)
C8H3F6S-*
 DMSO

N  Param.: 19.71

sN Param.: 0.86		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
4-(trifluoromethyl)thiophenolate (in DMSO)
C7H4F3S-*
 DMSO

N  Param.: 21.30

sN Param.: 0.86		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
3-(trifluoromethyl)thiophenolate (in DMSO)
C7H4F3S-*
 DMSO

N  Param.: 21.75

sN Param.: 0.86		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
3-chlorothiophenolate (in DMSO)
C6H4ClS-*
 DMSO

N  Param.: 22.50

sN Param.: 0.78		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
4-bromothiophenolate (in DMSO)
C6H4BrS-*
 DMSO

N  Param.: 22.80

sN Param.: 0.78		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
thiophenolate (in DMSO)
C6H5S-*
 DMSO

N  Param.: 23.36

sN Param.: 0.74		***J. Org. Chem. 2021, 86, 5965-5972
10.1021/acs.joc.1c00025
1,3-dimethyl-2-methyleneimidazolidine (in THF)
C6H12N2*
 THF

N  Param.: 18.11

sN Param.: 0.68		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838