Isochalkogenoureas
| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
(S)-3,3-difluoro-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine (in CH2Cl2)  |
dichloromethane | N Param.: 10.83 sN Param.: 0.80 |  | ARKIVOC 2024, (4), 202312093 10.24820/ark.5550190[...] |
(R)-2-(tert-butyl)-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine |
dichloromethane | N Param.: 12.95 sN Param.: 0.58 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
2,3,5,6-tetrahydroimidazo[2,1-b]thiazole |
dichloromethane | N Param.: 12.98 sN Param.: 0.81 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
3,5,6,7-tetrahydro-2H-imidazo[2,1-b][1,3]thiazine |
dichloromethane | N Param.: 13.00 sN Param.: 0.83 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
IU5 |
dichloromethane | N Param.: 13.01 sN Param.: 0.73 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
ITU2 |
dichloromethane | N Param.: 13.06 sN Param.: 0.73 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
IU3 |
dichloromethane | N Param.: 13.31 sN Param.: 0.69 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole |
dichloromethane | N Param.: 13.42 sN Param.: 0.73 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
(S)-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine |
dichloromethane | N Param.: 13.45 sN Param.: 0.72 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
DHPB (3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine) |
dichloromethane | N Param.: 13.86 sN Param.: 0.78 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
ITU1 |
dichloromethane | N Param.: 13.86 sN Param.: 0.68 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
2,3,4,6,7,8-hexahydropyrimido[2,1-b][1,3]thiazine |
dichloromethane | N Param.: 14.10 sN Param.: 0.82 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
ISeU5 (in THF) |
THF | N Param.: 14.19 sN Param.: 0.77 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
ISeU2 |
dichloromethane | N Param.: 14.27 sN Param.: 0.63 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
ISeU4 |
dichloromethane | N Param.: 14.42 sN Param.: 0.67 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
THTP (3,5,6,7-tetrahydro-2H-thiazolo[3,2-a]pyrimidine) |
dichloromethane | N Param.: 14.45 sN Param.: 0.78 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
ITeU2 |
dichloromethane | N Param.: 14.62 sN Param.: 0.66 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
(2S,3S)-3-isopropyl-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine |
dichloromethane | N Param.: 14.96 sN Param.: 0.64 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
ISeU3 |
dichloromethane | N Param.: 15.16 sN Param.: 0.66 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
ISeU1 |
dichloromethane | N Param.: 15.26 sN Param.: 0.60 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
(R)-2-benzhydryl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine |
dichloromethane | N Param.: 15.30 sN Param.: 0.55 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
ISeU5 (in MeCN) |
MeCN | N Param.: 15.84 sN Param.: 0.57 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
ISeU5 (in DCM) |
dichloromethane | N Param.: 16.11 sN Param.: 0.58 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |
(R)-2-isopropyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine |
dichloromethane | N Param.: 16.50 sN Param.: 0.48 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
ITeU3 |
dichloromethane | N Param.: 16.63 sN Param.: 0.65 | | Angew. Chem. Int. Ed. 2025, , in print 10.1002/anie.202514865 |