Mayr's Database of Reactivity Parameters

Nucleophiles

19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 Found 1310 molecules, displaying page 23 of 27 Results per page 10|50|100|all
Name Solvent Reactivity
Parameters 		Classification Reference
(title or year)
1-(4-(dimethylamino)pyridin-1-ium-1-yl)-2-oxo-2-phenylethan-1-ide (in DMSO)
C15H17N2O*
 DMSO

N  Param.: 21.61

sN Param.: 0.58		***J. Am. Chem. Soc. 2013, 135, 15216-15224
10.1021/ja407885h
1-(3-chloropyridin-1-ium-1-yl)-2-oxo-2-phenylethan-1-ide (in DMSO)
C13H11ClNO*
 DMSO

N  Param.: 17.98

sN Param.: 0.63		***J. Am. Chem. Soc. 2013, 135, 15216-15224
10.1021/ja407885h
1-(2-methyl-4,5-dihydro-1H-imidazol-1-yl)ethanone (in CH2Cl2)
C6H10N2O*
 dichloromethane

N  Param.: 10.03

sN Param.: 0.75		***Eur. J. Org. Chem. 2013, , 3369-3377
10.1002/ejoc.201300213
1-(1-cyclohexenyl)-4-methylpiperazine
C11H20N2*
 dichloromethane

N  Param.: 12.51

sN Param.: 0.80		*Chem. Eur. J. 2003, 9, 2209-2218
10.1002/chem.200204666
1-((diphenylmethylene)amino)-2-ethoxy-2-oxoethan-1-ide (in DMSO)
*
 DMSO

N  Param.: 26.95

sN Param.: 0.52		***Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
1-((4-chlorobenzylidene)amino)-2-ethoxy-2-oxoethan-1-ide (in DMSO)
*
 DMSO

N  Param.: 29.02

sN Param.: 0.49		**Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
1,6-dimethyl-2-methylene-1,2-dihydropyridine (in DMSO)
C8H11N*
 DMSO

N  Param.: 20.76

sN Param.: 0.60		***Eur. J. Org. Chem. 2024, 27, e202400373
10.1002/ejoc.202400373
1,6-bis(trimethylsilyl)hexane
*
 dichloromethane

N  Param.: -4.70

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,4-pentadiene
C5H8*
 dichloromethane

N  Param.: -2.99

sN Param.: 0.97		*J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
1,4-dimethylcyclohexa-1,4-diene (in CH2Cl2)
C8H12*
 dichloromethane

N  Param.: 1.88

sN Param.: 0.96		**J. Am. Chem. Soc. 2014, 136, 13863-13873
10.1021/ja507598y
1,4-dihydronaphthalene (in MeCN)
C10H10*
 MeCN

N  Param.: -2.50

sN Param.: 1.00		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,4-dihydronaphthalene
C10H10*
 dichloromethane

N  Param.: -0.07

sN Param.: 1.03		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
1,4-cyclohexadiene (in MeCN)
*
 MeCN

N  Param.: 0.35

sN Param.: 0.98		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,4-cyclohexadiene
C6H8*
 dichloromethane

N  Param.: 0.09

sN Param.: 0.98		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
1,3-oxazolidin-2-one anion (in DMSO)
*
 DMSO

N  Param.: 22.40

sN Param.: 0.59		***J. Org. Chem. 2010, 75, 5250-5258
10.1021/jo1009883
1,3-dioxolane
C3H6O2*
 dichloromethane

N  Param.: -2.86

sN Param.: 0.80		***Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,3-dioxepane
*
 dichloromethane

N  Param.: -3.80

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,3-dimethylimidazolidin-2-imine
C5H11N3*
 dichloromethane

N  Param.: 12.46

sN Param.: 0.87		***ChemCatChem 2012, 4, 993-999
10.1002/cctc.201200143
1,3-dimethylbarbiturate anion (in DMSO)
C6H7N2O3*
 DMSO

N  Param.: 17.46

sN Param.: 0.72		***J. Org. Chem. 2017, 82, 8476-8488
10.1021/acs.joc.7b01223
1,3-dimethyl-2-methyleneimidazolidine (in THF)
C6H12N2*
 THF

N  Param.: 18.11

sN Param.: 0.68		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimethyl-2-methylenehexahydropyrimidine (in THF)
C7H14N2*
 THF

N  Param.: 18.68

sN Param.: 0.63		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimethyl-2-methylene-2,3-dihydro-1H-benzo[d]imidazole
C10H12N2*
 THF

N  Param.: 19.84

sN Param.: 0.58		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimethyl-2-methylene-1,2-dihydropyridine (in MeCN)
C8H11N*
 MeCN

N  Param.: 19.69

sN Param.: 0.61		***Eur. J. Org. Chem. 2024, 27, e202400373
10.1002/ejoc.202400373
1,3-dimethyl-2-methylene-1,2-dihydropyridine (in DMSO)
C8H11N*
 DMSO

N  Param.: 19.91

sN Param.: 0.62		***Eur. J. Org. Chem. 2024, 27, e202400373
10.1002/ejoc.202400373
1,3-dimethoxybenzene
C8H10O2*
 dichloromethane

N  Param.: 2.48

sN Param.: 1.09		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
1,3-dimesityl-4,5-dihydro-1H-imidazol-3-ium-2-ide (in THF)
C21H26N2*
 THF

N  Param.: 23.35

sN Param.: 0.40		***Angew. Chem. Int. Ed. 2011, 50, 6915-6919
10.1002/anie.201102435
1,3-dimesityl-2-methylene-2,3-dihydro-1H-imidazole (in THF)
C22H26N2*
 THF

N  Param.: 17.80

sN Param.: 0.79		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimesityl-2,3-dihydro-1H-1,3,2-diazaphosphole (in MeCN)
C20H25N2P*
 MeCN

N  Param.: 17.68

sN Param.: 0.68		***Angew. Chem. Int. Ed. 2019, 58, 5983-5987
10.1002/anie.201901456
1,3-dimesityl-1H-imidazol-3-ium-2-ide (in THF)
C21H24N2*
 THF

N  Param.: 21.72

sN Param.: 0.45		***Angew. Chem. Int. Ed. 2011, 50, 6915-6919
10.1002/anie.201102435
1,3-Diisopropyl-4-methylene-5-phenyl-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C15H21N3*
 THF

N  Param.: 30.25

sN Param.: 0.54		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-diethyl-thiobarbiturate anion (in DMSO)
C8H11N2O2S*
 DMSO

N  Param.: 14.90

sN Param.: 0.80		***J. Org. Chem. 2017, 82, 8476-8488
10.1021/acs.joc.7b01223
1,3-diethoxy-2-fluoro-1,3-dioxopropan-2-ide (in DMSO)
C7H10FO4*
 DMSO

N  Param.: 20.63

sN Param.: 0.76		***Angew. Chem. Int. Ed. 2016, 55, 12845-12848
10.1002/anie.201605616
1,3-diaminopropane (in water)
C3H10N2*
 water

N  Param.: 14.02

sN Param.: 0.54		***J. Org. Chem. 2007, 72, 3679-3688
10.1021/jo062586z
1,3-di-tert-butyl-2,3-dihydro-1H-benzo[d][1,3,2]diazaphosphole (in MeCN)
C14H23N2P*
 MeCN

N  Param.: 20.93

sN Param.: 0.43		***Angew. Chem. Int. Ed. 2019, 58, 5983-5987
10.1002/anie.201901456
1,3-di-tert-butyl-2,3-dihydro-1H-1,3,2-diazaphosphole (in MeCN)
C10H21N2P*
 MeCN

N  Param.: 25.54

sN Param.: 0.35		***Angew. Chem. Int. Ed. 2019, 58, 5983-5987
10.1002/anie.201901456
1,3-di-tert-butyl-1,3,2-diazaphospholidine (in MeCN)
C10H23N2P*
 MeCN

N  Param.: 18.74

sN Param.: 0.47		***Angew. Chem. Int. Ed. 2019, 58, 5983-5987
10.1002/anie.201901456
1,3-di-tert-butyl-1,3,2-diazaphosphinane (in MeCN)
C11H25N2P*
 MeCN

N  Param.: 13.46

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2019, 58, 5983-5987
10.1002/anie.201901456
1,3-bis(trimethylstannyl)propane (in MeCN)
*
 MeCN

N  Param.: -1.70

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,3-bis(trimethylsilyl)propane
*
 dichloromethane/MeCN mix

N  Param.: -5.30

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,3-bis(trimethylgermyl)propane (in MeCN)
*
 MeCN

N  Param.: -3.40

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1,3-Bis(2,6-diisopropylphenyl)-5-methylene-4-(2,4,6-triisopropylphenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-4-ide (in THF)
C35H39F6N3*
 THF

N  Param.: 21.36

sN Param.: 0.42		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-5-methylene-4-(2,4,6-triisopropylphenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-4-ide (in THF)
C42H59N3*
 THF

N  Param.: 20.78

sN Param.: 0.61		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-5-methyl-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C28H39N3*
 THF

N  Param.: 24.86

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-5-(4-methoxyphenyl)-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C34H43N3O*
 THF

N  Param.: 23.55

sN Param.: 0.56		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-4-methylene-5-phenyl-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C33H41N3*
 THF

N  Param.: 22.80

sN Param.: 0.60		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-4-methylene-5-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C34H40F3N3*
 THF

N  Param.: 22.30

sN Param.: 0.49		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-2,3-dihydro-1H-1,3,2-diazaphosphole (in MeCN)
C26H37N2P*
 MeCN

N  Param.: 19.85

sN Param.: 0.34		***Angew. Chem. Int. Ed. 2019, 58, 5983-5987
10.1002/anie.201901456
1,3,5-trimethylcyclohexa-1,4-diene (in CH2Cl2)
C9H14*
 dichloromethane

N  Param.: 4.95

sN Param.: 0.79		**J. Am. Chem. Soc. 2014, 136, 13863-13873
10.1021/ja507598y
1,3,5-trimethyl-2-methylene-1,2-dihydropyridine (in DMSO)
C9H13N*
 DMSO

N  Param.: 21.16

sN Param.: 0.59		***Eur. J. Org. Chem. 2024, 27, e202400373
10.1002/ejoc.202400373
1,3,4-triphenyl-1H-1,2,4-triazol-4-ium-5-ide (in THF)
C20H15N3*
 THF

N  Param.: 14.07

sN Param.: 0.84		***Angew. Chem. Int. Ed. 2011, 50, 6915-6919
10.1002/anie.201102435