Nucleophiles
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« Back Forward » Found 1292 molecules, displaying page 3 of 13 Results per page
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| Name | Solvent |
Reactivity Parameters |
Classification |
Reference (title or year) |
|---|---|---|---|---|
1-(1-cyclohexenyl)-4-methylpiperazine  |
dichloromethane | N Param.: 12.51 sN Param.: 0.80 |  | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(2-methyl-4,5-dihydro-1H-imidazol-1-yl)ethanone (in CH2Cl2) |
dichloromethane | N Param.: 10.03 sN Param.: 0.75 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
1-(3-chloropyridin-1-ium-1-yl)-2-oxo-2-phenylethan-1-ide (in DMSO) |
DMSO | N Param.: 17.98 sN Param.: 0.63 | | J. Am. Chem. Soc. 2013, 135, 15216-15224 10.1021/ja407885h |
1-(4-(dimethylamino)pyridin-1-ium-1-yl)-2-oxo-2-phenylethan-1-ide (in DMSO) |
DMSO | N Param.: 21.61 sN Param.: 0.58 | | J. Am. Chem. Soc. 2013, 135, 15216-15224 10.1021/ja407885h |
1-(benzylideneamino)-2-ethoxy-2-oxoethan-1-ide (in DMSO) |
DMSO | N Param.: 29.10 sN Param.: 0.50 | | Tetrahedron 2019, 75, 459-463 10.1016/j.tet.2018.1[...] |
1-(ethoxycarbonyl)-2-oxocyclododecan-1-ide (in DMSO) |
DMSO | N Param.: 20.60 sN Param.: 0.63 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
1-(ethoxycarbonyl)-2-oxocycloheptan-1-ide |
DMSO | N Param.: 19.53 sN Param.: 0.83 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
1-(ethoxycarbonyl)-2-oxocyclohexan-1-ide (in DMSO) |
DMSO | N Param.: 18.32 sN Param.: 0.84 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
1-(ethoxycarbonyl)-2-oxocyclooctan-1-ide (in DMSO) |
DMSO | N Param.: 20.02 sN Param.: 0.76 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
1-(ethoxycarbonyl)-2-oxocyclopentan-1-ide (in DMSO) |
DMSO | N Param.: 18.63 sN Param.: 0.82 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
1-(isoquinolin-2-ium-2-yl)-2-oxo-2-phenylethan-1-ide (in DMSO) |
DMSO | N Param.: 20.08 sN Param.: 0.57 | | J. Am. Chem. Soc. 2013, 135, 15216-15224 10.1021/ja407885h |
1-(N-morpholino)cyclohexene |
dichloromethane | N Param.: 11.40 sN Param.: 0.83 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-(N-morpholino)cyclopentene |
dichloromethane | N Param.: 13.41 sN Param.: 0.82 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(N-piperidino)cyclohexene |
dichloromethane | N Param.: 13.36 sN Param.: 0.81 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-(N-piperidino)cyclohexene (in MeCN) |
MeCN | N Param.: 14.02 sN Param.: 0.76 | | J. Am. Chem. Soc. 2013, 135, 6579-6587 10.1021/ja401106x |
1-(N-piperidino)cyclopentene |
dichloromethane | N Param.: 15.06 sN Param.: 0.82 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(N-pyrrolidino)cyclohexene |
dichloromethane | N Param.: 14.91 sN Param.: 0.86 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(N-pyrrolidino)cyclohexene (in MeCN) |
MeCN | N Param.: 16.42 sN Param.: 0.70 | | Angew. Chem. Int. Ed. 2010, 49, 9526-9529 10.1002/anie.201004344 |
1-(N-pyrrolidino)cyclopentene |
dichloromethane | N Param.: 15.91 sN Param.: 0.86 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(p-tolyl)-1-(trimethylsilyl)ethene |
dichloromethane | N Param.: -0.65 sN Param.: 1.59 | | Chem. Eur. J. 2014, 20, 1103-1110 10.1002/chem.201303215 |
1-(perfluorophenyl)-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 1.47 sN Param.: 0.89 | | Org. Lett. 2012, 14, 3990-3993 10.1021/ol301766w |
1-(phenylethynyl)pyrrolidin-2-one |
dichloromethane | N Param.: 3.12 sN Param.: 0.85 | | Angew. Chem. Int. Ed. 2014, 53, 4968-4971 10.1002/anie.201402055 |
1-(phenylmethylamino)cyclohexene |
dichloromethane | N Param.: 10.73 sN Param.: 0.81 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(phenylmethylamino)cyclopentene |
dichloromethane | N Param.: 12.90 sN Param.: 0.79 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-(trimethylsiloxy)-3,4-dihydronaphthalene (in MeCN) |
MeCN | N Param.: 5.06 sN Param.: 0.91 | | Synthesis 2019, 51, 1157-1170 10.1055/s-0037-1611634 |
1-(trimethylsiloxy)buta-1,3-diene |
dichloromethane | N Param.: 4.60 sN Param.: 0.90 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
1-(trimethylsiloxy)cycloheptene |
dichloromethane | N Param.: 6.62 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
1-(trimethylsiloxy)cyclohexene |
dichloromethane | N Param.: 5.21 sN Param.: 1.00 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-(trimethylsiloxy)cyclooctene |
dichloromethane | N Param.: 6.77 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
1-(trimethylsiloxy)cyclopentene |
dichloromethane | N Param.: 6.57 sN Param.: 0.93 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-(trimethylsiloxy)cyclopentene (in MeCN) |
MeCN | N Param.: 6.43 sN Param.: 0.89 | | Chem. Asian J. 2012, 7, 1401-1407 10.1002/asia.201101046 |
1-(trimethylsilyl)-imidazole (in MeCN) |
MeCN | N Param.: 11.43 sN Param.: 0.79 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-(triphenylsiloxy)cyclopentene |
dichloromethane | N Param.: 5.76 sN Param.: 1.02 | | Eur. J. Org. Chem. 2005, , 1760-1764 10.1002/ejoc.200400706 |
1-(tris(pentafluorophenyl)siloxy)-cyclopentene |
dichloromethane | N Param.: 1.38 sN Param.: 0.93 | | Eur. J. Org. Chem. 2005, , 1760-1764 10.1002/ejoc.200400706 |
1-(tris(trimethylsilyl)siloxy)cyclohexene |
dichloromethane | N Param.: 5.07 sN Param.: 0.91 | | Org. Lett. 2010, 12, 5206-5209 10.1021/ol102220e |
1-aminopropan-2-ol (in DMSO) |
DMSO | N Param.: 15.47 sN Param.: 0.65 | | J. Am. Chem. Soc. 2009, 131, 11392-11401 10.1021/ja903207b |
1-benzyl-2-phenyl-4,5-dihydro-1H-imidazole (in CH2Cl2) |
dichloromethane | N Param.: 13.11 sN Param.: 0.83 | | Eur. J. Org. Chem. 2013, , 3369-3377 10.1002/ejoc.201300213 |
1-butoxy-1-(t-butyl-dimethylsiloxy)ethene |
dichloromethane | N Param.: 10.32 sN Param.: 0.79 | | Eur. J. Org. Chem. 2004, , 2791-2796 10.1002/ejoc.200400134 |
1-butoxy-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 10.21 sN Param.: 0.82 | | Eur. J. Org. Chem. 2004, , 2791-2796 10.1002/ejoc.200400134 |
1-ethinylcyclohexenyl-Co2(CO)6 |
dichloromethane | N Param.: -0.44 sN Param.: 1.06 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-ethoxy-2-methyl-1,3-dioxobutan-2-ide (in DMSO) |
DMSO | N Param.: 19.58 sN Param.: 0.73 | | Eur. J. Org. Chem. 2015, , 7594-7601 10.1002/ejoc.201501107 |
1-ethoxy-3-(4-nitrophenyl)-1,3-dioxopropan-2-ide (in DMSO) |
DMSO | N Param.: 16.26 sN Param.: 0.83 | | J. Am. Chem. Soc. 2018, 140, 11474-11486 10.1021/jacs.8b07147 |
1-hexene |
dichloromethane | N Param.: -2.77 sN Param.: 1.41 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
1-mesityl-3-methyl-5-methylene-2,4,6-triphenyl-2,5-dihydropyridin-1-ium-2-ide (in THF) |
THF | N Param.: 26.16 sN Param.: 0.52 | | Angew. Chem. Int. Ed. 2024, , e202318283 10.1002/anie.202318283 |
1-methoxy-2-methyl-1-(trimethylsiloxy)propene |
dichloromethane | N Param.: 9.00 sN Param.: 0.98 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-methoxy-2-methyl-1-(trimethylsiloxy)propene (in MeCN) |
MeCN | N Param.: 9.11 sN Param.: 0.88 | | J. Am. Chem. Soc. 2013, 135, 6579-6587 10.1021/ja401106x |
1-methyl uracil anion (in DMSO) |
DMSO | N Param.: 16.36 sN Param.: 0.69 | | Chem. Eur. J. 2012, 18, 127-137 10.1002/chem.201102411 |
1-methyl uracil anion (in water) |
water | N Param.: 8.54 sN Param.: 0.77 | | Chem. Eur. J. 2012, 18, 127-137 10.1002/chem.201102411 |
1-methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine (MeTBD) |
dichloromethane | N Param.: 14.43 sN Param.: 0.81 | | ChemCatChem 2012, 4, 993-999 10.1002/cctc.201200143 |
1-methyl-2-phenylpyrrolidine (in CH2Cl2) |
dichloromethane | N Param.: 16.80 sN Param.: 0.49 | | J. Phys. Org. Chem. 2016, 29, 759-767 10.1002/poc.3580 |
1-methyl-2-phenylpyrrolidine (in MeCN) |
MeCN | N Param.: 15.70 sN Param.: 0.54 | | J. Phys. Org. Chem. 2016, 29, 759-767 10.1002/poc.3580 |
1-methyl-4-(N-morpholino)tetrahydropyridine |
dichloromethane | N Param.: 12.03 sN Param.: 0.80 | | Chem. Eur. J. 2003, 9, 2209-2218 10.1002/chem.200204666 |
1-methyl-4-vinyl-benzene |
dichloromethane | N Param.: 1.70 sN Param.: 1.06 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-methyl-benzimidazole (in MeCN) |
MeCN | N Param.: 10.37 sN Param.: 0.82 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-methyl-benzotriazole (in MeCN) |
MeCN | N Param.: 7.77 sN Param.: 0.76 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-methyl-imidazole (in MeCN) |
MeCN | N Param.: 11.90 sN Param.: 0.73 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-methyl-imidazole (in water) |
water | N Param.: 9.91 sN Param.: 0.55 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-methylcyclohexene |
dichloromethane | N Param.: 0.08 sN Param.: 1.15 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-methylcyclopentene |
dichloromethane | N Param.: 1.18 sN Param.: 1.17 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
1-methylsiletane |
dichloromethane | N Param.: 2.30 sN Param.: 0.75 |  | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1-methylsilolane |
dichloromethane | N Param.: 2.20 sN Param.: 0.75 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1-phenoxy-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 8.23 sN Param.: 0.81 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-phenyl-1-(trimethylsiloxy)ethene |
dichloromethane | N Param.: 6.22 sN Param.: 0.96 | | J. Am. Chem. Soc. 2001, 123, 9500-9512 10.1021/ja010890y |
1-phenyl-imidazole (in MeCN) |
MeCN | N Param.: 11.31 sN Param.: 0.67 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
1-phenyl-N-(phenylmethyl)methanimine (in CH2Cl2) |
dichloromethane | N Param.: 7.90 sN Param.: 0.76 | | Z. Naturforsch. B 2013, 68b, 693-699 10.5560/ZNB.2013-3085 |
1-pyrrolidino-3,4-dihydronaphthalene (in MeCN) |
MeCN | N Param.: 14.09 sN Param.: 0.66 | | Synthesis 2019, 51, 1157-1170 10.1055/s-0037-1611634 |
10% ethanol/90% MeCN (v/v) |
EtOH-MeCN mix | N Param.: 5.19 sN Param.: 0.96 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
10% methanol/90% MeCN (v/v) |
MeOH-MeCN mix | N Param.: 5.55 sN Param.: 0.97 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
10% water/90% acetone (v/v) |
water-acetone mix | N Param.: 5.70 sN Param.: 0.85 | | Angew. Chem. Int. Ed. 2004, 43, 2302-2305 10.1002/anie.200353468 |
10% water/90% HFIP (w/w) |
water-HFIP mix | N Param.: 0.96 sN Param.: 0.93 | | J. Phys. Org. Chem. 2013, 26, 59-63 10.1002/poc.3064 |
10% water/90% MeCN (v/v) |
water-MeCN mix | N Param.: 4.56 sN Param.: 0.94 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
10% water/90%EtOH (v/v) |
water-EtOH mix | N Param.: 7.03 sN Param.: 0.86 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
10% water/90%TFE (v/v) |
water-TFE mix | N Param.: 2.93 sN Param.: 0.88 | | J. Am. Chem. Soc. 2004, 126, 5174-5181 10.1021/ja031828z |
10-methyl-9,10-dihydroacridine |
dichloromethane | N Param.: 5.54 sN Param.: 0.90 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
10-methyl-9,10-dihydroacridine (in MeCN) |
MeCN | N Param.: 4.00 sN Param.: 0.70 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
1H-indole-5-carboxylic acid |
MeCN | N Param.: 3.97 sN Param.: 1.10 | | J. Org. Chem. 2006, 71, 9088-9095 10.1021/jo0614339 |
2% water/98% HFIP (w/w) |
water-HFIP mix | N Param.: -1.62 sN Param.: 1.10 | | J. Phys. Org. Chem. 2013, 26, 59-63 10.1002/poc.3064 |
2,2,2-trifluoroethanolate (in water) |
water | N Param.: 12.66 sN Param.: 0.59 | | J. Am. Chem. Soc. 2003, 125, 286-295 10.1021/ja021010y |
2,2,2-trifluoroethylamine (in 91M9AN) |
MeOH-MeCN mix | N Param.: 10.20 sN Param.: 0.92 | | Angew. Chem. Int. Ed. 2006, 45, 3869-3874 10.1002/anie.200600542 |
2,2,2-trifluoroethylamine (in DMSO) |
DMSO | N Param.: 12.15 sN Param.: 0.65 | | J. Am. Chem. Soc. 2003, 125, 286-295 10.1021/ja021010y |
2,2,2-trifluoroethylamine (in MeCN) |
MeCN | N Param.: 10.13 sN Param.: 0.75 | | Eur. J. Org. Chem. 2009, , 6379-6385 10.1002/ejoc.200900925 |
2,2-dimethyl-5-(4-nitrobenzyl)-4,6-dioxo-1,3-dioxan-5-ide (in DMSO) |
DMSO | N Param.: 12.02 sN Param.: 1.17 | | Chem. Eur. J. 2014, 20, 11069-11077 10.1002/chem.201403161 |
2,2-dimethylpyrrolidine |
MeCN | N Param.: 13.96 sN Param.: 0.76 | | J. Am. Chem. Soc. 2020, 142, 1526-1547 10.1021/jacs.9b11877 |
2,3,3-trimethyl-but-1-ene |
dichloromethane | N Param.: 0.06 sN Param.: 1.07 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine |
dichloromethane | N Param.: 16.16 sN Param.: 0.75 | | ChemCatChem 2012, 4, 993-999 10.1002/cctc.201200143 |
2,3,4,6,7,8-hexahydropyrimido[2,1-b][1,3]thiazine |
dichloromethane | N Param.: 14.10 sN Param.: 0.82 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole (TBO) |
dichloromethane | N Param.: 14.44 sN Param.: 0.79 | | ChemCatChem 2012, 4, 993-999 10.1002/cctc.201200143 |
2,3,5,6-tetrahydroimidazo[2,1-b]thiazole |
dichloromethane | N Param.: 12.98 sN Param.: 0.81 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole |
dichloromethane | N Param.: 13.42 sN Param.: 0.73 | | J. Org. Chem. 2011, 76, 5104-5112 10.1021/jo200803x |
2,3-dihydrofuran |
dichloromethane | N Param.: 4.37 sN Param.: 0.90 | | Eur. J. Org. Chem. 2005, , 1760-1764 10.1002/ejoc.200400706 |
2,3-dimethyl-but-1-ene |
dichloromethane | N Param.: 0.65 sN Param.: 1.00 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
2,3-dimethyl-buta-1,3-diene |
dichloromethane | N Param.: 1.17 sN Param.: 1.00 | | Acc. Chem. Res. 2003, 36, 66-77 10.1021/ar020094c |
2,4,4-trimethyl-pent-1-ene |
dichloromethane | N Param.: 0.79 sN Param.: 1.07 | | J. Am. Chem. Soc. 2012, 134, 13902-13911 10.1021/ja306522b |
2,4,5-trimethyl-1,3-dioxolane (anti) |
dichloromethane | N Param.: -3.00 sN Param.: 0.80 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
2,4,5-trimethyl-1,3-dioxolane (syn) |
dichloromethane | N Param.: -2.50 sN Param.: 0.80 | | Chem. Eur. J. 2013, 19, 249-263 10.1002/chem.201202839 |
2,4,6-trimethylpyridine (in CH2Cl2) |
dichloromethane | N Param.: 9.34 sN Param.: 0.71 | | Synthesis 2017, 49, 3495-3504 10.1055/s-0036-1590504 |
2,4,6-trimethylpyridine (in MeCN) |
MeCN | N Param.: 9.39 sN Param.: 0.60 | | Synthesis 2017, 49, 3495-3504 10.1055/s-0036-1590504 |
2,4,6-trimethylstyrene |
dichloromethane | N Param.: 0.68 sN Param.: 1.09 | | Macromolecules 2005, 38, 33-40 10.1021/ma048389o |
2,4-dimethyl-imidazole (in MeCN) |
MeCN | N Param.: 11.51 sN Param.: 0.84 | | Org. Biomol. Chem. 2010, 8, 1929-1935 10.1039/c000965b |
2,4-dimethyl-imidazole anion (in DMSO) |
DMSO | N Param.: 20.69 sN Param.: 0.60 | | Chem. Eur. J. 2012, 18, 127-137 10.1002/chem.201102411 |