Mayr's Database of Reactivity Parameters

C-Nucleophiles

For reactivities of structurally related compounds go to: Nucleophiles
1 | 2 | 3 | 4 | 5 | 6 Forward » Found 562 molecules, displaying page 6 of 6 Results per page 10|50|100|all
Name Solvent Reactivity
Parameters 		Classification Reference
(title or year)
(E)-1-(2-(4-nitrophenyl)-1-phenylvinyl)pyrrolidine (in MeCN)
*
 MeCN

N  Param.: 10.42

sN Param.: 0.82		***Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
(E)-1-(1,2-diphenylvinyl)piperidine (in MeCN)
*
 MeCN

N  Param.: 9.94

sN Param.: 0.86		***Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
(E)-4-(1,2-diphenylvinyl)morpholine (in MeCN)
*
 MeCN

N  Param.: 8.78

sN Param.: 0.83		***Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
(E)-beta-(N-piperidino)styrene (in MeCN)
*
 MeCN

N  Param.: 13.84

sN Param.: 0.73		***Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
(E)-4-styrylmorpholine
*
 MeCN

N  Param.: 11.66

sN Param.: 0.83		***Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
alpha-(N-piperidino)styrene (in MeCN)
C13H17N*
 MeCN

N  Param.: 11.60

sN Param.: 0.80		*Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
alpha-(N-morpholino)styrene (in MeCN)
C12H15NO*
 MeCN

N  Param.: 10.30

sN Param.: 0.80		*Chem. Eur. J. 2018, 24, 5901-5910
10.1002/chem.201705962
(p-nitrophenyl)diazomethane
*
 dichloromethane

N  Param.: 7.17

sN Param.: 0.83		***J. Am. Chem. Soc. 2018, 140, 16758-16772
10.1021/jacs.8b09995
(p-cyanophenyl)diazomethane
*
 dichloromethane

N  Param.: 7.66

sN Param.: 0.80		***J. Am. Chem. Soc. 2018, 140, 16758-16772
10.1021/jacs.8b09995
(p-bromophenyl)diazomethane
*
 dichloromethane

N  Param.: 8.87

sN Param.: 0.82		***J. Am. Chem. Soc. 2018, 140, 16758-16772
10.1021/jacs.8b09995
1-ethoxy-3-(4-nitrophenyl)-1,3-dioxopropan-2-ide (in DMSO)
C11H10NO5-*
 DMSO

N  Param.: 16.26

sN Param.: 0.83		***J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147
1-((diphenylmethylene)amino)-2-ethoxy-2-oxoethan-1-ide (in DMSO)
*
 DMSO

N  Param.: 26.95

sN Param.: 0.52		***Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
2-(tert-butoxy)-1-((diphenylmethylene)amino)-2-oxoethan-1-ide (in DMSO)
C19H20NO2-*
 DMSO

N  Param.: 27.77

sN Param.: 0.47		***Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
1-(benzylideneamino)-2-ethoxy-2-oxoethan-1-ide (in DMSO)
*
 DMSO

N  Param.: 29.10

sN Param.: 0.50		*Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
1-((4-chlorobenzylidene)amino)-2-ethoxy-2-oxoethan-1-ide (in DMSO)
*
 DMSO

N  Param.: 29.02

sN Param.: 0.49		**Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
2-(benzylideneamino)-1-ethoxy-1-oxopropan-2-ide (in DMSO)
*
 DMSO

N  Param.: 30.82

sN Param.: 0.41		**Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
cyano((diphenylmethylene)amino)methanide
*
 DMSO

N  Param.: 29.50

sN Param.: 0.50		*Tetrahedron 2019, 75, 459-463
10.1016/j.tet.2018.1[...]
(Z)-1,2-diphenyl-1-(trimethylsiloxy)ethene (in MeCN)
C17H20OSi*
 MeCN

N  Param.: 3.00

sN Param.: 0.83		***Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
(Z)-1-phenyl-1-(trimethylsiloxy)propene (in MeCN)
C12H18OSi*
 MeCN

N  Param.: 5.18

sN Param.: 0.94		***Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
3-(trimethylsiloxy)-1H-indene (in MeCN)
C12H16OSi*
 MeCN

N  Param.: 7.32

sN Param.: 0.82		***Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
1-(trimethylsiloxy)-3,4-dihydronaphthalene (in MeCN)
C13H18OSi*
 MeCN

N  Param.: 5.06

sN Param.: 0.91		***Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
3-pyrrolidino-1H-indene (in MeCN)
C13H15N*
 MeCN

N  Param.: 15.27

sN Param.: 0.93		***Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
1-pyrrolidino-3,4-dihydronaphthalene (in MeCN)
C14H17N*
 MeCN

N  Param.: 14.09

sN Param.: 0.66		***Synthesis 2019, 51, 1157-1170
10.1055/s-0037-1611634
anion of 4-(trifluoromethyl)benzyl trifluoromethyl sulfone (in MeCN)
C9H5F6O2S*
 MeCN

N  Param.: 16.15

sN Param.: 0.99		***J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960
anion of 4-cyanobenzyl trifluoromethyl sulfone (in MeCN)
C9H5F3NO2S*
 MeCN

N  Param.: 15.62

sN Param.: 0.99		***J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960
anion of 4-nitrobenzyl-CN (in MeCN)
C8H5N2O2*
 MeCN

N  Param.: 20.10

sN Param.: 0.71		***J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960
anion of (4-NO2-C6H4)CH2SO2Ph (in MeCN)
C13H10NO4S*
 MeCN

N  Param.: 19.90

sN Param.: 0.66		***J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960
1,3-dimethyl-2-methyleneimidazolidine (in THF)
C6H12N2*
 THF

N  Param.: 18.11

sN Param.: 0.68		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimethyl-2-methylenehexahydropyrimidine (in THF)
C7H14N2*
 THF

N  Param.: 18.68

sN Param.: 0.63		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimesityl-2-methylene-2,3-dihydro-1H-imidazole (in THF)
C22H26N2*
 THF

N  Param.: 17.80

sN Param.: 0.79		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
1,3-dimethyl-2-methylene-2,3-dihydro-1H-benzo[d]imidazole
C10H12N2*
 THF

N  Param.: 19.84

sN Param.: 0.58		***J. Org. Chem. 2021, 86, 2974-2985
10.1021/acs.joc.0c02838
lithium 4,4,5,5-tetramethyl-2-phenyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolan-2-uide (in MeCN)
C15H22BLiO2*
 MeCN

N  Param.: 11.00

sN Param.: 0.57		***J. Am. Chem. Soc. 2022, 144, 16118-16130
10.1021/jacs.2c06493
3-diazoindolin-2-one
C8H5N3O*
 dichloromethane

N  Param.: 3.16

sN Param.: 1.03		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazoindan-1-one
C9H6N2O*
 dichloromethane

N  Param.: 5.61

sN Param.: 0.65		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazocyclohexanone
C6H8N2O*
 dichloromethane

N  Param.: 3.44

sN Param.: 0.83		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazo-1-tetralone
C10H8N2O*
 dichloromethane

N  Param.: 3.51

sN Param.: 0.86		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazoindandione
C9H4N2O2*
 dichloromethane

N  Param.: 0.16

sN Param.: 0.86		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazo-1-benzosuberone
C11H10N2O*
 dichloromethane

N  Param.: 2.72

sN Param.: 0.96		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-diazobenzothiophen-3(2H)-one
C8H4N2OS*
 dichloromethane

N  Param.: 0.40

sN Param.: 0.93		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
2-((2,2,5,5-tetramethyl-1-(prop-1-en-1-yl)-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C12H19N3S*
 MeCN

N  Param.: 9.25

sN Param.: 0.84		***Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-((2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C17H21N3S*
 MeCN

N  Param.: 7.74

sN Param.: 0.87		***Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
2-((2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in CH2Cl2)
C17H21N3S*
 dichloromethane

N  Param.: 7.06

sN Param.: 1.11		***Chem. Commun. 2023, 59, 8091-8084
10.1039/d3cc01912h
1,3-Bis(2,6-diisopropylphenyl)-5-methylene-4-(2,4,6-triisopropylphenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-4-ide (in THF)
C35H39F6N3*
 THF

N  Param.: 21.36

sN Param.: 0.42		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-4-methylene-5-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C34H40F3N3*
 THF

N  Param.: 22.30

sN Param.: 0.49		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-5-(4-methoxyphenyl)-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C34H43N3O*
 THF

N  Param.: 23.55

sN Param.: 0.56		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Bis(2,6-diisopropylphenyl)-5-methylene-4-(2,4,6-triisopropylphenyl)-4,5-dihydro-1H-1,2,3-triazol-3-ium-4-ide (in THF)
C42H59N3*
 THF

N  Param.: 20.78

sN Param.: 0.61		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-Diisopropyl-4-methylene-5-phenyl-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C15H21N3*
 THF

N  Param.: 30.25

sN Param.: 0.54		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
5-(tert-Butyl)-1,3-diisopropyl-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C13H25N3*
 THF

N  Param.: 31.92

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-4-methylene-5-phenyl-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C33H41N3*
 THF

N  Param.: 22.80

sN Param.: 0.60		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
1,3-bis(2,6-diisopropylphenyl)-5-methyl-4-methylene-4,5-dihydro-1H-1,2,3-triazol-3-ium-5-ide (in THF)
C28H39N3*
 THF

N  Param.: 24.86

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2023, 62, e202309790
10.1002/anie.202309790
(E)-2-((1-(but-1-en-1-yl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-imidazol-4-yl)thio)acetonitrile (in MeCN)
C13H21N3S*
 MeCN

N  Param.: 9.23

sN Param.: 0.74		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in MeCN)
C17H24N2S*
 MeCN

N  Param.: 8.12

sN Param.: 0.88		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-13-(ethylthio)-6-styryl-6,12-diazadispiro[4.1.47.25]tridec-12-ene (in MeCN)
C21H28N2S*
 MeCN

N  Param.: 7.79

sN Param.: 0.87		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-(3-phenylprop-1-en-1-yl)-2,5-dihydro-1H-imidazole (in MeCN)
C18H26N2S*
 MeCN

N  Param.: 9.64

sN Param.: 0.70		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-(3-phenylbut-1-en-1-yl)-2,5-dihydro-1H-imidazole (in MeCN)
C19H28N2S*
 MeCN

N  Param.: 7.92

sN Param.: 0.73		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(benzylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in MeCN)
C22H26N2S*
 MeCN

N  Param.: 8.30

sN Param.: 0.84		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
diazocyclopentadiene (in CH2Cl2)
C5H4N2*
 dichloromethane

N  Param.: 4.84

sN Param.: 1.06		***Synthesis 2023, 55, 354-358
10.1055/s-0041-1737327
(E)-2,2,3,5,5-pentamethyl-1-styrylimidazolidin-4-one (in MeCN)
C16H22N2O*
 MeCN

N  Param.: 7.10

sN Param.: 0.82		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-2,2,3,5,5-pentamethyl-1-styrylimidazolidine-4-thione (in MeCN)
C16H22N2S*
 MeCN

N  Param.: 6.49

sN Param.: 0.83		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(ethylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in CH2Cl2)
C17H24N2S *
 dichloromethane

N  Param.: 8.13

sN Param.: 0.97		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
(E)-4-(benzylthio)-2,2,5,5-tetramethyl-1-styryl-2,5-dihydro-1H-imidazole (in CH2Cl2)
C22H26N2S *
 dichloromethane

N  Param.: 7.99

sN Param.: 0.98		***Chem. Eur. J. 2023, , EarlyView
10.1002/chem.202302764
1-mesityl-3-methyl-5-methylene-2,4,6-triphenyl-2,5-dihydropyridin-1-ium-2-ide (in THF)
C34H31N*
 THF

N  Param.: 26.16

sN Param.: 0.52		***Angew. Chem. Int. Ed. 2024, , e202318283
10.1002/anie.202318283