| 1,2-diaza-1,3-diene 1d |
DMSO | E Param.: -15.38 |  | Chem. Eur. J. 2010, 16, 12008-12016
10.1002/chem.201000828 |
| phenyl isocyanate |
MeCN | E Param.: -15.38 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| 1,2-diaza-1,3-diene 1f |
MeOH | E Param.: -15.30 | | Chem. Eur. J. 2010, 16, 12008-12016
10.1002/chem.201000828 |
| 1-phenylprop-2-en-1-one (in DMSO) |
DMSO | E Param.: -15.25 | | J. Am. Chem. Soc. 2017, 139, 13318-13329
10.1021/jacs.7b05106 |
| (E)-6-(4-methoxybenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -15.20 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| (E)-N-(4-(dimethylamino)benzylidene)-4-methylbenzenesulfonamide (in DMSO) |
DMSO | E Param.: -15.09 | | J. Am. Chem. Soc. 2011, 133, 8240-8251
10.1021/ja200820m |
| 2,6-di-tert.butyl-4-(3-fluorobenzylidene)cyclohexa-2,5-dienone |
| E Param.: -15.03 | | Eur. J. Org. Chem. 2009, , 3203-3211
10.1002/ejoc.200900299 |
| 1,2-diaza-1,3-diene 1c |
DMSO | E Param.: -14.91 | | Chem. Eur. J. 2010, 16, 12008-12016
10.1002/chem.201000828 |
| 1,2-diaza-1,3-diene 1e |
MeOH | E Param.: -14.90 | | Chem. Eur. J. 2010, 16, 12008-12016
10.1002/chem.201000828 |
| 3-nitro-1-tosyl-1H-indole |
| E Param.: -14.87 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| (E)-6-(4-methylbenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -14.85 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| 4-methoxy-<i>trans-beta</i>-nitrostyrene |
| E Param.: -14.70 | | J. Org. Chem. 2011, 76, 9370-9378
10.1021/jo201678u |
| jul-indan-1,3-dione |
| E Param.: -14.68 | | Org. Biomol. Chem. 2007, 5, 3020-3026
10.1039/b708025e |
| 4-bromo-3-nitro-1-tosyl-1H-indole |
| E Param.: -14.60 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| 2-(4-methoxybenzylidene)-1,3-dithiane 1,1,3,3-tetraoxide |
DMSO | E Param.: -14.55 | | Chem. Asian J. 2012, 7, 1401-1407
10.1002/asia.201101046 |
| ((2-(2-iodophenyl)propan-2-yl)oxy)(trifluoromethyl)sulfane |
| E Param.: -14.52 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| 2,6-di-tert.butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone |
| E Param.: -14.50 | | Eur. J. Org. Chem. 2009, , 3203-3211
10.1002/ejoc.200900299 |
| (E)-6-benzylidenebenzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -14.47 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| [(1,3-Diarylallyl)Pd(PPh3)2]+ (Aryl = 4-(dimethylamino)phenyl) |
| E Param.: -14.46 | | Organometallics 2012, 31, 2416-2424
10.1021/om3000357 |
| 2,6-di-tert.butyl-4-(4-nitrobenzylidene)cyclohexa-2,5-dienone |
| E Param.: -14.36 | | Eur. J. Org. Chem. 2009, , 3203-3211
10.1002/ejoc.200900299 |
| 4-methyl-<i>trans-beta</i>-nitrostyrene |
| E Param.: -14.23 | | J. Org. Chem. 2011, 76, 9370-9378
10.1021/jo201678u |
| (E)-tert-butyl benzylidenecarbamate (in DMSO) |
DMSO | E Param.: -14.22 | | J. Am. Chem. Soc. 2011, 133, 8240-8251
10.1021/ja200820m |
| [(1,3-Diarylallyl)Pd(PPh3)2]+ (Aryl = 3,5-difluorophenyl) |
| E Param.: -14.21 | | Organometallics 2012, 31, 2416-2424
10.1021/om3000357 |
| [(1,3-Diarylallyl)Pd(PPh3)2]+ (Aryl = Ph) |
| E Param.: -14.14 | | Organometallics 2012, 31, 2416-2424
10.1021/om3000357 |
| ethyl 3-nitro-1H-indole-1-carboxylate |
| E Param.: -14.10 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| N-methyl maleimide |
DMSO | E Param.: -14.07 | | Eur. J. Org. Chem. 2014, , 2956-2963
10.1002/ejoc.201301779 |
| (E)-6-(3-fluorobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -14.00 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| (E)-6-(4-chlorobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -13.99 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| jul Meldrum's acid |
| E Param.: -13.97 | | J. Org. Chem. 2008, 73, 2738-2745
10.1021/jo702590s |
| 1,2-diaza-1,3-diene 1b |
DMSO | E Param.: -13.90 | | Chem. Eur. J. 2010, 16, 12008-12016
10.1002/chem.201000828 |
| (2-(4-methoxyphenyl)ethene-1,1-diyldisulfonyl)dibenzene |
DMSO | E Param.: -13.88 | | Chem. Asian J. 2012, 7, 1401-1407
10.1002/asia.201101046 |
| <i>trans-beta</i>-nitrostyrene |
| E Param.: -13.85 | | J. Org. Chem. 2011, 76, 9370-9378
10.1021/jo201678u |
| julBBS |
| E Param.: -13.84 | | J. Org. Chem. 2007, 72, 9170-9180
10.1021/jo071273g |
| p-chloranil (C-Cl) |
| E Param.: -13.84 | | J. Am. Chem. Soc. 2014, 136, 11499-11512
10.1021/ja505613b |
| ((2-phenylpropan-2-yl)oxy)(trifluoromethyl)sulfane |
| E Param.: -13.77 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| 2-(p-(dimethylamino)benzylidene)-indan-1,3-dione |
| E Param.: -13.56 | | Org. Biomol. Chem. 2007, 5, 3020-3026
10.1039/b708025e |
| (E)-6-(4-(trifluoromethyl)benzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -13.54 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| N-methyl-N-((trifluoromethyl)thio)-p-toluenesulfonamide |
| E Param.: -13.44 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| dma(Ph)2QM |
| E Param.: -13.39 | | Angew. Chem. Int. Ed. 2002, 41, 91-95
10.1002/1521-3773(20[...] |
| Umemoto I (tetrafluoroborate) |
| E Param.: -13.39 | | Eur. J. Org. Chem. 2024, 27, e202400085
10.1002/ejoc.202400085 |
| 4-bromo-<i>trans-beta</i>-nitrostyrene |
| E Param.: -13.37 | | J. Org. Chem. 2011, 76, 9370-9378
10.1021/jo201678u |
| p-(dimethylamino)benzylidenemalononitrile |
| E Param.: -13.30 | | J. Org. Chem. 2003, 68, 6880-6886
10.1021/jo0344182 |
| 1,2-diaza-1,3-diene 1a |
DMSO | E Param.: -13.28 | | Chem. Eur. J. 2010, 16, 12008-12016
10.1002/chem.201000828 |
| 1,3,5-trinitrobenzene |
| E Param.: -13.19 | | J. Org. Chem. 2005, 70, 6242-6253
10.1021/jo0505526 |
| (E)-6-(4-nitrobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -13.15 | | Chem. Eur. J. 2024, , e202403785
10.1002/chem.202403785 |
| Umemoto I (triflate) |
| E Param.: -13.08 | | Eur. J. Org. Chem. 2024, 27, e202400085
10.1002/ejoc.202400085 |
| (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide (in DMSO) |
DMSO | E Param.: -13.05 | | J. Am. Chem. Soc. 2011, 133, 8240-8251
10.1021/ja200820m |
| 2-(4-methoxybenzylidene)benzo[d][1,3]dithiole 1,1,3,3-tetraoxide |
DMSO | E Param.: -13.02 | | Chem. Asian J. 2012, 7, 1401-1407
10.1002/asia.201101046 |
| (2-phenylethene-1,1-diyldisulfonyl)dibenzene |
DMSO | E Param.: -12.93 | | Chem. Asian J. 2012, 7, 1401-1407
10.1002/asia.201101046 |
| benzaldehyde (in DMSO) |
DMSO | E Param.: -12.90 | | J. Am. Chem. Soc. 2018, 140, 5500-5515
10.1021/jacs.8b01657 |
| 3,6-dinitro-1-tosyl-1H-indole |
| E Param.: -12.90 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| Umemoto II (triflate) |
| E Param.: -12.80 | | Eur. J. Org. Chem. 2024, 27, e202400085
10.1002/ejoc.202400085 |
| dmaBBS |
| E Param.: -12.76 | | J. Org. Chem. 2007, 72, 9170-9180
10.1021/jo071273g |
| p-(dimethylamino)benzylidene Meldrum's acid |
| E Param.: -12.76 | | J. Org. Chem. 2008, 73, 2738-2745
10.1021/jo702590s |
| 4-cyano-<i>trans-beta</i>-nitrostyrene |
| E Param.: -12.61 | | J. Org. Chem. 2011, 76, 9370-9378
10.1021/jo201678u |
| N-(trifluoromethyl)thio)succinimide |
| E Param.: -12.56 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| 4-nitro-<i>trans-beta</i>-nitrostyrene |
| E Param.: -12.37 | | J. Org. Chem. 2011, 76, 9370-9378
10.1021/jo201678u |
| 2,4-dinitrothiophene |
| E Param.: -12.33 | | J. Org. Chem. 2005, 70, 6242-6253
10.1021/jo0505526 |
| 2,5-dichloroquinone (C-H) |
| E Param.: -12.28 | | J. Am. Chem. Soc. 2014, 136, 11499-11512
10.1021/ja505613b |
| di-tert-butyl azodicarboxylate |
MeCN | E Param.: -12.23 | | Chem. Eur. J. 2010, 16, 11670-11677
10.1002/chem.201001598 |
| ani(Ph)2QM |
| E Param.: -12.18 | | Angew. Chem. Int. Ed. 2002, 41, 91-95
10.1002/1521-3773(20[...] |
| p-chloranil (C=O) |
| E Param.: -12.13 | | J. Am. Chem. Soc. 2014, 136, 11499-11512
10.1021/ja505613b |
| ethenesulfonyl fluoride (ESF) |
DMSO | E Param.: -12.09 | | Angew. Chem. Int. Ed. 2016, 55, 12664-12667
10.1002/anie.201601875 |
| o-chloranil (C-Cl) |
| E Param.: -12.02 | | J. Am. Chem. Soc. 2014, 136, 11499-11512
10.1021/ja505613b |
| 2-cinnamoyl-1-(2,6-dimethoxyphenyl)-3-methyl-1H-imidazol-3-ium |
DMSO | E Param.: -12.02 | | Top. Catal. 2018, 61, 585-590
10.1007/s11244-018-0[...] |
| N-(trifluoromethyl)thio)phthalimide |
| E Param.: -11.92 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| jul(S)BBS |
| E Param.: -11.89 | | J. Org. Chem. 2007, 72, 9170-9180
10.1021/jo071273g |
| 2,6-diphenyl-4-benzylidenecyclohexa-2,5-dienone |
| E Param.: -11.87 | | Eur. J. Org. Chem. 2009, , 3203-3211
10.1002/ejoc.200900299 |
| N-(difluoromethyl)thio)phthalimide |
| E Param.: -11.86 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| 1-(tert-butyl)-2-cinnamoyl-3-methyl-1H-imidazol-3-ium |
DMSO | E Param.: -11.80 | | Top. Catal. 2018, 61, 585-590
10.1007/s11244-018-0[...] |
| 2-cinnamoyl-1-(4-methoxyphenyl)-3-methyl-1H-imidazol-3-ium |
DMSO | E Param.: -11.79 | | Top. Catal. 2018, 61, 585-590
10.1007/s11244-018-0[...] |
| 2-benzylidenebenzo[d][1,3]dithiole 1,1,3,3-tetraoxide |
DMSO | E Param.: -11.78 | | Chem. Asian J. 2012, 7, 1401-1407
10.1002/asia.201101046 |
| 2,6-di-tert-butyl-4-(2,2,2-trifluoroethylidene)cyclohexa-2,5-dien-1-one |
DMSO | E Param.: -11.68 | | Eur. J. Org. Chem. 2020, , 3812-3817
10.1002/ejoc.202000295 |
| 2-cinnamoyl-1,3-dimethyl-1H-imidazol-3-ium |
DMSO | E Param.: -11.52 | | Angew. Chem. Int. Ed. 2012, 51, 5234-5238
10.1002/anie.201109042 |
| (E)-N-benzylidene-4-methylbenzenesulfonamide (in DMSO) |
DMSO | E Param.: -11.50 | | J. Am. Chem. Soc. 2011, 133, 8240-8251
10.1021/ja200820m |
| 2-cinnamoyl-1-mesityl-3-methyl-1H-imidazol-3-ium |
DMSO | E Param.: -11.48 | | Top. Catal. 2018, 61, 585-590
10.1007/s11244-018-0[...] |
| 2-(p-methoxybenzylidene)-indan-1,3-dione |
| E Param.: -11.32 | | Org. Biomol. Chem. 2007, 5, 3020-3026
10.1039/b708025e |
| maleic anhydride |
DMSO | E Param.: -11.31 | | Eur. J. Org. Chem. 2014, , 2956-2963
10.1002/ejoc.201301779 |
| (4-NMe2)3-tritylium ion (= Crystal violet) |
| E Param.: -11.26 |  | J. Am. Chem. Soc. 2003, 125, 286-295
10.1021/ja021010y |
| 2,2,4-trichloro-1(2H)-naphthalenone |
MeCN | E Param.: -11.24 | | Org. Lett. 2010, 12, 2238-2241
10.1021/ol100592j |
| dicarbonyl(cyclopentadienyl)propene-iron(II) |
| E Param.: -11.20 | | Helv. Chim. Acta 2005, 88, 1754-1768
10.1002/hlca.200590137 |
| p-fluoranil (C-F) |
| E Param.: -11.12 | | J. Am. Chem. Soc. 2014, 136, 11499-11512
10.1021/ja505613b |
| p-(methoxy)benzylidenemalononitrile |
| E Param.: -10.80 | | J. Org. Chem. 2003, 68, 6880-6886
10.1021/jo0344182 |
| dma(S)BBS |
| E Param.: -10.73 | | J. Org. Chem. 2007, 72, 9170-9180
10.1021/jo071273g |
| diisopropyl azodicarboxylate |
MeCN | E Param.: -10.71 | | Chem. Eur. J. 2010, 16, 11670-11677
10.1002/chem.201001598 |
| p-AniCH=N+Me2 (in MeCN) |
MeCN | E Param.: -10.69 | | J. Am. Chem. Soc. 2013, 135, 6579-6587
10.1021/ja401106x |
| (S,E)-5-benzyl-1-((E)-3-(4-(dimethylamino)phenyl)allylidene)-2,2,3-trimethyl-4-oxoimidazolidin-1-ium |
dichloromethane | E Param.: -10.60 | | Asian J. Org. Chem. 2014, 3, 550-555
10.1002/ajoc.201402009 |
| 5,7,7-trichloro-8(7H)-quinolinone |
MeCN | E Param.: -10.48 | | Org. Lett. 2010, 12, 2238-2241
10.1021/ol100592j |
| N-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate |
| E Param.: -10.46 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
| aniBBS |
| E Param.: -10.37 | | J. Org. Chem. 2007, 72, 9170-9180
10.1021/jo071273g |
| pipN+=CH-CH-Ph |
| E Param.: -10.30 | | Angew. Chem. Int. Ed. 2008, 47, 8723-8726
10.1002/anie.200802889 |
| (4-NMe2)2-tritylium ion (= Malachite green) |
| E Param.: -10.29 | | J. Am. Chem. Soc. 2003, 125, 286-295
10.1021/ja021010y |
| p-(methoxy)benzylidene Meldrum's acid |
| E Param.: -10.28 | | J. Org. Chem. 2008, 73, 2738-2745
10.1021/jo702590s |
| bis(1,2-dimethylindol-3-yl)methylium ion |
| E Param.: -10.23 | | J. Org. Chem. 2015, 80, 8643-8656
10.1021/acs.joc.5b01298 |
| diethyl azodicarboxylate |
MeCN | E Param.: -10.15 | | Chem. Eur. J. 2010, 16, 11670-11677
10.1002/chem.201001598 |
| Pd-allyl cation |
| E Param.: -10.11 | | Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c |
| 2-benzylidene-indan-1,3-dione |
| E Param.: -10.11 | | Org. Biomol. Chem. 2007, 5, 3020-3026
10.1039/b708025e |
| 2-cinnamoyl-3-methyl-1-(perfluorophenyl)-1H-imidazol-3-ium |
DMSO | E Param.: -10.09 | | Top. Catal. 2018, 61, 585-590
10.1007/s11244-018-0[...] |
| (lil)2CH+ |
| E Param.: -10.04 | | J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y |
| N-fluoropyridinium tetrafluoroborate |
| E Param.: -9.89 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
C-Nucleophiles (572)
