Mayr's Database of Reactivity Parameters

Nucleophiles

1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 Found 1310 molecules, displaying page 2 of 14 Results per page 10|50|100|all
Name Solvent Reactivity
Parameters 		Classification Reference
(title or year)
2-(tris(trimethylsilyl)silyl)propene
C12H32Si4*
 dichloromethane

N  Param.: -0.31

sN Param.: 0.99		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
tetrabutylstannane
*
 dichloromethane

N  Param.: -0.30

sN Param.: 1.07		***Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(4-(tert-butyl)phenethyl)trimethylstannane
*
 1,2-dichloroethane

N  Param.: -0.30

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-(pentamethyldisilyl)propene
C8H20Si2*
 dichloromethane

N  Param.: -0.26

sN Param.: 0.95		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
norbornene
C7H10*
 dichloromethane

N  Param.: -0.25

sN Param.: 1.09		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
allyltriphenylsilane
C21H20Si*
 dichloromethane

N  Param.: -0.13

sN Param.: 1.21		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
5% water/95% HFIP (w/w)
*
 water-HFIP mix

N  Param.: -0.10

sN Param.: 0.97		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
(1H-inden-1-yl)trimethylsilane (in CH2Cl2)
C12H16Si*
 dichloromethane

N  Param.: -0.10

sN Param.: 1.05		***Angew. Chem. Int. Ed. 2015, 54, 12497-12500
10.1002/anie.201501385
1,4-dihydronaphthalene
C10H10*
 dichloromethane

N  Param.: -0.07

sN Param.: 1.03		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
phenylacetylene
C8H6*
 dichloromethane

N  Param.: -0.04

sN Param.: 0.77		***Angew. Chem. Int. Ed. 2014, 53, 4968-4971
10.1002/anie.201402055
phenylsilane
C6H8Si*
 dichloromethane

N  Param.: 0.06

sN Param.: 0.71		***Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2,3,3-trimethyl-but-1-ene
C7H14*
 dichloromethane

N  Param.: 0.06

sN Param.: 1.07		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
cyclohepta-1,3-diene
C7H10*
 dichloromethane

N  Param.: 0.06

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
1-methylcyclohexene
C7H12*
 dichloromethane

N  Param.: 0.08

sN Param.: 1.15		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
1,4-cyclohexadiene
C6H8*
 dichloromethane

N  Param.: 0.09

sN Param.: 0.98		***J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
tetraethylplumbane (in MeCN)
*
 MeCN

N  Param.: 0.10

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
3-methylanisole
C8H10O*
 dichloromethane

N  Param.: 0.13

sN Param.: 1.27		***J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
2-diazoindandione
C9H4N2O2*
 dichloromethane

N  Param.: 0.16

sN Param.: 0.86		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
hexylsilane
*
 dichloromethane

N  Param.: 0.19

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(4-methoxyphenethyl)trimethylstannane
*
 1,2-dichloroethane

N  Param.: 0.20

sN Param.: 1.10		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(2-methylallyl)benzene
C10H12*
 dichloromethane

N  Param.: 0.25

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
7% water/93% HFIP (w/w)
*
 water-HFIP mix

N  Param.: 0.34

sN Param.: 0.96		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
1,4-cyclohexadiene (in MeCN)
*
 MeCN

N  Param.: 0.35

sN Param.: 0.98		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-diazobenzothiophen-3(2H)-one
C8H4N2OS*
 dichloromethane

N  Param.: 0.40

sN Param.: 0.93		***Eur. J. Org. Chem. 2023, 26, e202300005
10.1002/ejoc.202300005
cycloheptatriene
C7H8*
 dichloromethane

N  Param.: 0.52

sN Param.: 0.97		*J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
2,4-dimethyl-penta-1,4-diene
C7H12*
 dichloromethane

N  Param.: 0.54

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
cycloheptatriene (in MeCN)
C7H8*
 MeCN

N  Param.: 0.55

sN Param.: 0.97		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-(tris(pentafluorophenyl)siloxy)-propene
C21H5F15OSi*
 dichloromethane

N  Param.: 0.58

sN Param.: 0.91		*Eur. J. Org. Chem. 2005, , 1760-1764
10.1002/ejoc.200400706
alpha-(pentamethyldisilyl)styrene
C13H22Si2*
 dichloromethane

N  Param.: 0.61

sN Param.: 1.01		***Chem. Eur. J. 2014, 20, 1103-1110
10.1002/chem.201303215
xanthene
C13H10O*
 dichloromethane

N  Param.: 0.64

sN Param.: 0.97		*J. Am. Chem. Soc. 2002, 124, 4076-4083
10.1021/ja0121538
2-methyl-but-2-ene
C5H10*
 dichloromethane

N  Param.: 0.65

sN Param.: 1.17		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
2,3-dimethyl-but-1-ene
C6H12*
 dichloromethane

N  Param.: 0.65

sN Param.: 1.00		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
(Z)-penta-1,3-diene
C5H8*
 dichloromethane

N  Param.: 0.66

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
cyclohexa-1,3-diene
C6H8*
 dichloromethane

N  Param.: 0.67

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(1S)-(-)-alpha-pinene
C10H16*
 dichloromethane

N  Param.: 0.68

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2,4,6-trimethylstyrene
C11H14*
 dichloromethane

N  Param.: 0.68

sN Param.: 1.09		***Macromolecules 2005, 38, 33-40
10.1021/ma048389o
styrene
C8H8*
 dichloromethane

N  Param.: 0.78

sN Param.: 0.95		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
2,4,4-trimethyl-pent-1-ene
C8H16*
 dichloromethane

N  Param.: 0.79

sN Param.: 1.07		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
chlorodimethylsilane
C2H7ClSi*
 dichloromethane

N  Param.: 0.79

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
(chloromethyl)dimethylsilane
C3H9ClSi*
 dichloromethane

N  Param.: 0.80

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-methyl-pent-1-ene
*
 dichloromethane

N  Param.: 0.84

sN Param.: 1.06		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
methyl(neopentyl)(phenyl)silane
C12H20Si*
 dichloromethane

N  Param.: 0.87

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
trimethyl(prenyl)silane
C8H18Si*
 dichloromethane

N  Param.: 0.90

sN Param.: 1.17		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
10% water/90% HFIP (w/w)
*
 water-HFIP mix

N  Param.: 0.96

sN Param.: 0.93		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
2-methyl-but-1-ene
C5H10*
 dichloromethane

N  Param.: 1.00

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-methyl-buta-1,3-diene (isoprene)
C5H8*
 dichloromethane

N  Param.: 1.10

sN Param.: 0.98		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
2-methylpropene (isobutylene)
C4H8*
 dichloromethane

N  Param.: 1.11

sN Param.: 0.98		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
trifluoroethanol
C2H3F3O*
 TFE

N  Param.: 1.11

sN Param.: 0.96		***J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
2,5-dimethyl-hexa-1,5-diene
C8H14*
 dichloromethane

N  Param.: 1.14

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
methylenecyclohexane
C7H12*
 dichloromethane

N  Param.: 1.16

sN Param.: 1.04		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
(E,E)-hexa-2,4-diene
C6H10*
 dichloromethane

N  Param.: 1.17

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2,3-dimethyl-buta-1,3-diene
C6H10*
 dichloromethane

N  Param.: 1.17

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
1-methylcyclopentene
C6H10*
 dichloromethane

N  Param.: 1.18

sN Param.: 1.17		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
allyltriphenylgermane
C21H20Ge*
 dichloromethane

N  Param.: 1.20

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(3-chlorobenzyl)dimethylsilane
C9H13ClSi*
 dichloromethane

N  Param.: 1.30

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
furan
C4H4O*
 dichloromethane

N  Param.: 1.33

sN Param.: 1.29		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
2-phenyl-4-(trimethylsilyl)but-1-en-3-ynyl-Co2(CO)6
*
 dichloromethane

N  Param.: 1.33

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-methylthiophene
C5H6S*
 dichloromethane

N  Param.: 1.35

sN Param.: 0.99		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
tetraisobutylstannane
*
 dichloromethane

N  Param.: 1.35

sN Param.: 1.10		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
1-(tris(pentafluorophenyl)siloxy)-cyclopentene
C23H7F15OSi*
 dichloromethane

N  Param.: 1.38

sN Param.: 0.93		*Eur. J. Org. Chem. 2005, , 1760-1764
10.1002/ejoc.200400706
1-(perfluorophenyl)-1-(trimethylsiloxy)ethene
*
 dichloromethane

N  Param.: 1.47

sN Param.: 0.89		***Org. Lett. 2012, 14, 3990-3993
10.1021/ol301766w
(E)-penta-1,3-diene
C5H8*
 dichloromethane

N  Param.: 1.49

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
50% water/50% HFIP (w/w)
*
 water-HFIP mix

N  Param.: 1.50

sN Param.: 1.03		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
HMn(CO)5
*
 dichloromethane

N  Param.: 1.50

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
methylenecyclododecane
C13H24*
 dichloromethane

N  Param.: 1.52

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
diphenylsilane
*
 dichloromethane

N  Param.: 1.52

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-(tributylstannyl)thiophene
C16H30SSn*
 dichloromethane

N  Param.: 1.53

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2,7-dimethylocta-1,7-diene
C10H18*
 dichloromethane

N  Param.: 1.58

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
HCr(CO)3Cp*
*
 dichloromethane

N  Param.: 1.60

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
methylenecyclobutane
C5H8*
 dichloromethane

N  Param.: 1.65

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
30% water/70% HFIP (w/w)
*
 water-HFIP mix

N  Param.: 1.65

sN Param.: 0.96		***J. Phys. Org. Chem. 2013, 26, 59-63
10.1002/poc.3064
allyltrimethylsilane
C6H14Si*
 dichloromethane

N  Param.: 1.68

sN Param.: 1.00		*****J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
tert-butyl indole-1-carboxylate
C13H15NO2*
 MeCN

N  Param.: 1.68

sN Param.: 1.26		***J. Am. Chem. Soc. 2013, 135, 6317-6324
10.1021/ja4017655
methylenecyclopentadecane
C16H30*
 dichloromethane

N  Param.: 1.69

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(Z)-but-2-enyltrimethylsilane
C7H16Si*
 dichloromethane

N  Param.: 1.69

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2,6-dimethyl-hepta-1,6-diene
C9H16*
 dichloromethane

N  Param.: 1.69

sN Param.: 1.00		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
1-methyl-4-vinyl-benzene
C9H10*
 dichloromethane

N  Param.: 1.70

sN Param.: 1.06		*****J. Am. Chem. Soc. 2001, 123, 9500-9512
10.1021/ja010890y
HW(CO)3Cp
*
 dichloromethane

N  Param.: 1.70

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
3-(trimethylsilyl)cyclopentene
C8H16Si*
 dichloromethane

N  Param.: 1.77

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
allyl-tert.butyl-dimethylsilane
C9H20Si*
 dichloromethane

N  Param.: 1.80

sN Param.: 0.95		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(5-methyl-furan-2-yl) MIDA boronate
*
 MeCN

N  Param.: 1.84

sN Param.: 1.26		**Chem. Sci. 2012, 3, 878-882
10.1039/c2sc00883a
1,4-dimethylcyclohexa-1,4-diene (in CH2Cl2)
C8H12*
 dichloromethane

N  Param.: 1.88

sN Param.: 0.96		**J. Am. Chem. Soc. 2014, 136, 13863-13873
10.1021/ja507598y
allyltriethylsilane
C9H20Si*
 dichloromethane

N  Param.: 1.93

sN Param.: 0.95		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
(E)-but-2-enyltrimethylsilane
C7H16Si*
 dichloromethane

N  Param.: 1.94

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
allyltris(trimethylsilyl)silane
*
 dichloromethane

N  Param.: 1.95

sN Param.: 0.98		***Org. Lett. 2010, 12, 5206-5209
10.1021/ol102220e
3-(trihexylsilyl)cyclopentene
C23H46Si*
 dichloromethane

N  Param.: 1.98

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
allyltriisopropylsilane
C12H26Si*
 dichloromethane

N  Param.: 2.04

sN Param.: 0.95		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
allyltri-n-butylsilane
C15H32Si*
 dichloromethane

N  Param.: 2.09

sN Param.: 0.95		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
allyltrihexylsilane
C21H44Si*
 dichloromethane

N  Param.: 2.11

sN Param.: 0.95		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
methyl(phenyl)silane
C7H10Si*
 dichloromethane

N  Param.: 2.13

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
2-(trimethylsilyl)furan
C7H12OSi*
 dichloromethane

N  Param.: 2.16

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
2-(triethylsilyl)furan
C10H18OSi*
 dichloromethane

N  Param.: 2.20

sN Param.: 1.10		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
1-methylsilolane
C5H12Si*
 dichloromethane

N  Param.: 2.20

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
cis-HMn(PCy3)(CO)4
*
 dichloromethane

N  Param.: 2.20

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
acetonitrile (in MeCN)
*
 MeCN

N  Param.: 2.23

sN Param.: 0.84		***J. Am. Chem. Soc. 2012, 134, 13902-13911
10.1021/ja306522b
methylenecycloheptane
C8H14*
 dichloromethane

N  Param.: 2.24

sN Param.: 0.90		*Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
dihexylsilane
*
 dichloromethane

N  Param.: 2.27

sN Param.: 0.73		*Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
cyclopentadiene
C5H6*
 dichloromethane

N  Param.: 2.30

sN Param.: 1.06		***Acc. Chem. Res. 2003, 36, 66-77
10.1021/ar020094c
1-methylsiletane
C4H10Si*
 dichloromethane

N  Param.: 2.30

sN Param.: 0.75		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839
cis-HMn(PPh3)(CO)4
*
 dichloromethane

N  Param.: 2.30

sN Param.: 0.80		-Chem. Eur. J. 2013, 19, 249-263
10.1002/chem.201202839