| oxan-4-one (in DMSO) |
DMSO | E Param.: -17.90 |  | J. Am. Chem. Soc. 2018, 140, 5500-5515
10.1021/jacs.8b01657 |
| thian-4-one (in DMSO) |
DMSO | E Param.: -16.90 | | J. Am. Chem. Soc. 2018, 140, 5500-5515
10.1021/jacs.8b01657 |
| 1,4-dioxaspiro[4.5]decan-8-one (in DMSO) |
DMSO | E Param.: -18.20 | | J. Am. Chem. Soc. 2018, 140, 5500-5515
10.1021/jacs.8b01657 |
| pentan-2-one (in DMSO) |
DMSO | E Param.: -22.30 | | J. Am. Chem. Soc. 2018, 140, 5500-5515
10.1021/jacs.8b01657 |
| 1-methylsulfanylpropan-2-one (in DMSO) |
DMSO | E Param.: -15.60 | | J. Am. Chem. Soc. 2018, 140, 5500-5515
10.1021/jacs.8b01657 |
| N-(phenylsulfonyl)-N-((trifluoromethyl)thio)benzenesulfonamide |
| E Param.: -6.06 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| N-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate |
| E Param.: -10.46 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
| N-fluoro-2,6-dichloropyridinium tetrafluoroborate |
| E Param.: -5.29 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
| Selectfluor |
| E Param.: -5.20 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
| NFSI |
MeCN | E Param.: -8.44 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
| N-fluoropyridinium tetrafluoroborate |
| E Param.: -9.89 | | J. Am. Chem. Soc. 2018, 140, 11474-11486
10.1021/jacs.8b07147 |
| N-(trifluoromethyl)thio)phthalimide |
| E Param.: -11.92 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| N-(trifluoromethyl)thio)saccharin |
| E Param.: -6.48 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| N-(trifluoromethyl)thio)succinimide |
| E Param.: -12.56 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| N-(difluoromethyl)thio)phthalimide |
| E Param.: -11.86 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| N-methyl-N-((trifluoromethyl)thio)-p-toluenesulfonamide |
| E Param.: -13.44 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| N-methyl-N-((trifluoromethyl)thio)-aniline |
| E Param.: -23.32 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| ((2-phenylpropan-2-yl)oxy)(trifluoromethyl)sulfane |
| E Param.: -13.77 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| ((2-(2-iodophenyl)propan-2-yl)oxy)(trifluoromethyl)sulfane |
| E Param.: -14.52 | | Angew. Chem. Int. Ed. 2018, 57, 12690-12695
10.1002/anie.201805859 |
| 4-phenylbut-3-yn-2-one |
| E Param.: -16.90 |  | Angew. Chem. Int. Ed. 2019, 58, 17704-17708
10.1002/anie.201909803 |
| hex-3-yn-2-one |
| E Param.: -17.90 | | Angew. Chem. Int. Ed. 2019, 58, 17704-17708
10.1002/anie.201909803 |
| butynone |
| E Param.: -16.60 | | Angew. Chem. Int. Ed. 2019, 58, 17704-17708
10.1002/anie.201909803 |
| (E)-2,6-di-tert-butyl-4-(3-phenylallylidene)cyclohexa-2,5-dien-1-one |
DMSO | E Param.: -17.00 | | Org. Lett. 2020, 22, 2182-2186
10.1021/acs.orglett.[...] |
| E)-2,6-di-tert-butyl-4-(3-(4-chlorophenyl)allylidene)cyclohexa-2,5-dien-1-one |
DMSO | E Param.: -16.84 | | Org. Lett. 2020, 22, 2182-2186
10.1021/acs.orglett.[...] |
| (E)-2,6-di-tert-butyl-4-(3-(4-nitrophenyl)allylidene)cyclohexa-2,5-dien-1-one |
DMSO | E Param.: -16.25 | | Org. Lett. 2020, 22, 2182-2186
10.1021/acs.orglett.[...] |
| (E)-2,6-di-tert-butyl-4-(3-(4-methoxyphenyl)allylidene)cyclohexa-2,5-dien-1-one |
DMSO | E Param.: -17.42 | | Org. Lett. 2020, 22, 2182-2186
10.1021/acs.orglett.[...] |
| 2,6-di-tert-butyl-4-(2,2,2-trifluoroethylidene)cyclohexa-2,5-dien-1-one |
DMSO | E Param.: -11.68 | | Eur. J. Org. Chem. 2020, , 3812-3817
10.1002/ejoc.202000295 |
| phenyl isocyanate |
MeCN | E Param.: -15.38 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| p-tosyl isocyanate |
MeCN | E Param.: -7.69 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| phenyl isothiocyanate |
DMSO | E Param.: -18.15 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| p-nitrophenyl isothiocyanate |
DMSO | E Param.: -15.89 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| diphenylcarbodiimide |
DMSO | E Param.: -20.14 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| carbon disulfide |
DMSO | E Param.: -17.70 | | J. Am. Chem. Soc. 2020, 142, 8383-8402
10.1021/jacs.0c01960 |
| 3-methylcyclopentenone |
DMSO | E Param.: -28.90 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| 2-methylcyclopentenone |
DMSO | E Param.: -22.10 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| cyclopentenone |
DMSO | E Param.: -20.60 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| furan-2(5H)-one |
DMSO | E Param.: -20.70 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| 2-methylcyclohexenone |
DMSO | E Param.: -27.50 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| cyclohexenone |
DMSO | E Param.: -22.10 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| dihydro-2H-pyran-2-one |
DMSO | E Param.: -21.80 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| 3-methylenetetrahydropyran-2-one |
DMSO | E Param.: -19.50 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| 3-methylenedihydrofuranone |
DMSO | E Param.: -19.40 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| ethyl 3-nitro-1H-indole-1-carboxylate |
| E Param.: -14.10 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| 3-nitro-1-tosyl-1H-indole |
| E Param.: -14.87 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| 4-bromo-3-nitro-1-tosyl-1H-indole |
| E Param.: -14.60 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| 3-methylcyclohexenone |
DMSO | E Param.: -29.60 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| 3,6-dinitro-1-tosyl-1H-indole |
| E Param.: -12.90 | | Chem. Commun. 2021, 57, 10071-10074
10.1039/d1cc04074j |
| cycloheptenone |
DMSO | E Param.: -22.00 | | Chem. Sci. 2021, 12, 4850-4865
10.1039/D0SC06628A |
| methyl diazoacetate |
| E Param.: -18.50 | | Chem. Eur. J. 2022, 28, e202201376
10.1002/chem.202201376 |
| dimethyl diazomalonate |
| E Param.: -18.20 | | Chem. Eur. J. 2022, 28, e202201376
10.1002/chem.202201376 |
| (p-nitrophenyl)diazomethane |
| E Param.: -18.30 | | Chem. Eur. J. 2022, 28, e202201376
10.1002/chem.202201376 |
| diphenyldiazomethane |
| E Param.: -21.40 | | Chem. Eur. J. 2022, 28, e202201376
10.1002/chem.202201376 |
| Umemoto I (triflate) |
| E Param.: -13.08 | | Eur. J. Org. Chem. 2024, 27, e202400085
10.1002/ejoc.202400085 |
| Umemoto I (tetrafluoroborate) |
| E Param.: -13.39 | | Eur. J. Org. Chem. 2024, 27, e202400085
10.1002/ejoc.202400085 |
| Umemoto II (triflate) |
| E Param.: -12.80 | | Eur. J. Org. Chem. 2024, 27, e202400085
10.1002/ejoc.202400085 |
| (E)-6-(4-nitrobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -13.15 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(4-(trifluoromethyl)benzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -13.54 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(3-fluorobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -14.00 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(4-chlorobenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -13.99 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-benzylidenebenzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -14.47 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(4-methylbenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -14.85 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(4-methoxybenzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -15.20 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(4-(dimethylamino)benzylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -16.07 | | Chem. Eur. J. 2025, 31, e202403785
10.1002/chem.202403785 |
| (E)-6-(furan-2-ylmethylene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -15.73 | | Org. Biomol. Chem. 2025, 23, 827-834
10.1039/D4OB01855A |
| (E)-6-((1-methyl-1H-pyrrol-2-yl)methylene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -17.03 | | Org. Biomol. Chem. 2025, 23, 827-834
10.1039/D4OB01855A |
| (E)-6-((1-methyl-1H-indol-2-yl)methylene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -15.55 | | Org. Biomol. Chem. 2025, 23, 827-834
10.1039/D4OB01855A |
| (E)-6-((E)-3-phenylallylidene)benzo[d][1,3]dioxol-5(6H)-one |
| E Param.: -16.00 | | Org. Biomol. Chem. 2025, 23, 827-834
10.1039/D4OB01855A |
| 2,6-di-tert-butyl-4-methylenecyclohexa-2,5-dien-1-one |
| E Param.: -11.17 | | Chem. Eur. J. 2025, , in print
10.1002/chem.202501224 |
| 2,6-di-tert-butyl-4-(methoxymethylene)cyclohexa-2,5-dien-1-one |
| E Param.: -15.10 | | Chem. Eur. J. 2025, , in print
10.1002/chem.202501224 |
| 2-(3,5-di-tert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)acetonitrile |
| E Param.: -11.88 | | Chem. Eur. J. 2025, , in print
10.1002/chem.202501224 |
| ethyl 2-(3,5-di-tert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)acetate |
| E Param.: -12.01 | | Chem. Eur. J. 2025, , in print
10.1002/chem.202501224 |
| 2,6-di-tert-butyl-4-ethylidenecyclohexa-2,5-dien-1-one |
| E Param.: -13.68 | | Chem. Eur. J. 2025, , in print
10.1002/chem.202501224 |
| 4-benzylidene-2,6-di-tert-butylcyclohexa-2,5-dien-1-one |
| E Param.: -15.58 | | Chem. Eur. J. 2025, , in print
10.1002/chem.202501224 |
C-Nucleophiles (572)
